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Even mild skin toxicities worsen dermatology-specific QoL and can disrupt mood and social function. The review synthesizes PubMed evidence and expert guidance to evaluate proactive skincare interventions, including gentle pH-balanced cleansing, ceramide- or urea-based moisturizers, and broad-spectrum photoprotection, while emphasizing prevention of photosensitivity and secondary skin cancers.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/skin-health-in-oncology-evidence-based-skin-care-for-cancer-patients/354309/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/skin-health-in-oncology-evidence-based-skin-care-for-cancer-patients/354309.png","ImageObject",300,407,{"name":92,"@type":93},"Mimi","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-22",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",12,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why is skin care important during cancer treatment?","Question",{"text":113,"@type":114},"Cancer and systemic therapies frequently cause cutaneous adverse events such as xerosis, pruritus, dermatitis, and radiation-induced damage, which negatively affect quality of life and can reduce treatment adherence.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What proactive skin-care measures does the review support?",{"text":118,"@type":114},"The review supports gentle pH-balanced cleansers, ceramide- or urea-based moisturizers to restore the barrier, and broad-spectrum photoprotection to reduce symptom severity and improve quality of life.",{"name":120,"@type":111,"acceptedAnswer":121},"How does photoprotection relate to long-term skin risk in oncology?",{"text":122,"@type":114},"Chemotherapy and immunomodulatory therapies increase photosensitivity, accelerate photoaging, and raise the risk of secondary skin cancers, making vigilant sun protection essential.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},354309,1790227428,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":105,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":41},2336477974920,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","The Oncologist, 2026, 31, oyag194  \n[https://doi.org/10.1093/oncolo/oyag194](https://doi.org/10.1093/oncolo/oyag194)  \n[Published: June 1](Published: June 1), 2026  \nReview Article  \nSkin health in oncology: evidence-based skin care for cancer patients  \nAlexander Kaminsky1, , Sara Suhl1, Yoni Sacknovitz1, Gary K. Schwartz, MD2, Sandhya Deverapalli, MD3, Larisa J. Geskin, MD4,*,   \n1Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032, United States 2Case Comprehensive Cancer Center, Cleveland, OH 44106, United States  \n3Tufts Medical Center, Boston, MA 02111, United States  \n4 Department of Dermatology, Columbia University Irving Medical Center, New York, NY 10032, United States  \n*Corresponding author: Larisa J. Geskin, MD, Department of Dermatology, Columbia University Irving Medical Center, 161 Fort Washington Ave, 12th floor, New York, NY 10032, USA ([ljg2145@cumc.columbia.edu](ljg2145@cumc.columbia.edu)) .  \nAbstract  \nBackground: Cancer and its treatments frequently compromise skin integrity, leading to xerosis, pruritus, dermatitis, radiation-induced skin damage, and secondary infections. These cutaneous adverse events (cAEs) are not merely superficial; they profoundly impact patient quality of life (QoL), contributing to physical discomfort, psychosocial distress, and  \npoorer treatment adherence. Even mild skin toxicities elevate dermatology-specific QoL measures, affecting mood and social function. Additionally, new targeted therapies, such as daraxonrasib—a KRAS inhibitor under development for pancreatic cancer—can cause a dose-limiting acneiform facial rash.  \nMethods: In this study, relevant literature on skin care in cancer patients was identified using PubMed. Evidence from clinical studies, reviews, and expert guidelines was summarized.  \nResults: Evidence supports proactive skincare with gentle pH-balanced cleansers, ceramide- or urea-based moisturizers, and broad-spectrum photoprotection to lessen symptom severity and improve QoL. Sun protection remains essential because chemotherapy and immunomodulatory therapies increase photosensitivity, accelerate photoaging, and raise the risk of secondary skin cancers. Supportive skincare interventions have also shown emotional and functional benefits, including improved mood and self-image during chemotherapy and radiation treatment.  \nConclusion: Despite strong data supporting moisturization, barrier repair, and photoprotection, oncologic treatment plans often overlook these interventions. By integrating dermatologic education and skincare maintenance into standard oncologic practice, we can minimize cAEs, foster treatment compliance, and enhance patients’ physical comfort and psychosocial well-being. This narrative review synthesizes mechanistic insights, clinical evidence, and practical recommendations for oncologists to champion comprehensive skincare in all cancer patients, whether directly affected by skin issues or not. Key words: oncology; skin care; sun protection; moisturization; review  \nImplications for Practice  \nThis manuscript highlights how fundamental skincare steps—such as moisturizing and sun protection—can make a tremendous difference for cancer patients. Treatments and diseases often cause painful or visible skin problems that hurt quality of life and may disrupt care. By including safe, evidence-based skincare in cancer treatment plans, doctors can help patients feel more comfortable, stay on therapy longer, and maintain a stronger sense of self during a difficult time.  \nReceived: August 6, 2025. Accepted: May 12, 2026  \n© The Author(s) 2026. Published by Oxford University Press.  \nThis is an Open Access article distributed under the terms of the Creative Commons Attribution License ([https://creativecommons.org/licenses/by/4.0/](https://creativecommons.org/licenses/by/4.0/)), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.  \nIntroduction ","cbCaidjF4DdzLIsA","https://ap.wps.com/l/cbCaidjF4DdzLIsA","pdf",1503802,"English","# Abstract\n# Background\n# Methods\n# Results\n# Conclusion\n# Implications for Practice\n# Introduction","[{\"question\":\"Why is skin care important during cancer treatment?\",\"answer\":\"Cancer and systemic therapies frequently cause cutaneous adverse events such as xerosis, pruritus, dermatitis, and radiation-induced damage, which negatively affect quality of life and can reduce treatment adherence.\"},{\"question\":\"What proactive skin-care measures does the review support?\",\"answer\":\"The review supports gentle pH-balanced cleansers, ceramide- or urea-based moisturizers to restore the barrier, and broad-spectrum photoprotection to reduce symptom severity and improve quality of life.\"},{\"question\":\"How does photoprotection relate to long-term skin risk in oncology?\",\"answer\":\"Chemotherapy and immunomodulatory therapies increase photosensitivity, accelerate photoaging, and raise the risk of secondary skin cancers, making vigilant sun protection essential.\"}]","Skin health in oncology: evidence-based skin care for cancer patients | PDF",1790110002]