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A multi-center retrospective study collected 50 elderly patients with acute HZO treated with short-term peripheral nerve stimulation (PNS) or supraorbital nerve pulsed radiofrequency (PRF), with all patients followed for 12 months. Pain intensity and sleep quality were assessed using VAS, BNI, and PSQI, with outcomes demonstrating superior improvements for PNS and a lower PHN incidence at follow-up.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/short-term-peripheral-nerve-stimulation-or-pulsed-radiofrequency-in-elderly-patients-with-acute-herpes-zoster-ophthalmicus-multi-center-retrospective-study/433800/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/short-term-peripheral-nerve-stimulation-or-pulsed-radiofrequency-in-elderly-patients-with-acute-herpes-zoster-ophthalmicus-multi-center-retrospective-study/433800.png","ImageObject",300,407,{"name":92,"@type":93},"Noah","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What clinical problem does the study address in elderly patients?","Question",{"text":112,"@type":113},"Elderly patients with herpes zoster ophthalmicus (HZO) have a high risk of progressing to postherpetic neuralgia (PHN). The study focuses on early interventions to reduce PHN occurrence and improve outcomes.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were patients treated and what follow-up duration was used?",{"text":117,"@type":113},"Fifty elderly patients with acute HZO received short-term peripheral nerve stimulation (PNS) or supraorbital nerve pulsed radiofrequency (PRF). All patients completed a 12-month follow-up period.",{"name":119,"@type":110,"acceptedAnswer":120},"Which assessment tools were used to evaluate outcomes?",{"text":121,"@type":113},"Pain intensity and sleep quality were evaluated using the Visual Analog Scale (VAS) and Pittsburgh Sleep Quality Index (PSQI). Neurologic outcomes were assessed using Barrow Neurological Institute (BNI) scores.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},433800,1790721517,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},8796095462418,"https://ap-avatar.wpscdn.com/avatar/80000253c1241d02b47?x-image-process=image/resize,m_fixed,w_180,h_180&k=1778826106357471780","Korean J Pain 2026;39(1):116-124 [https://doi.org/10.3344/kjp.25297](https://doi.org/10.3344/kjp.25297)[ ](https://doi.org/10.3344/kjp.25297)[pISSN 2005-9159](pISSN 2005-9159), eISSN 2093-0569  \nClinical Research Article  \nShort-term peripheral nerve stimulation or pulsed radiofrequency in elderly patients with acute herpes zoster ophthalmicus: multi-center retrospective study  \nYi Yan1,2, *, Zhiwei Wu1,2, *, Quan Wan3, Xuexue Zhang1,2, Daying Zhang1,2, Fan Yang4, Xintian Cao1,2, Changxi Li5, and Yong Zhang1,2  \n1 Pain Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China, 2Jiangxi Key Laboratory of Trauma, Burn and Pain Medicine, Nanchang, China  \n3 Pain Medicine, Zhejiang Provincial People’s Hospital, Hangzhou, China  \n4 Pain Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China 5 Pain Medicine, GuiQian International General Hospital, Guiyang, China  \nABSTRACT  \nBackground: Elderly patients with herpes zoster ophthalmicus (HZO) have a high risk to progress to postherpetic neuralgia (PHN). Thus, early implementation of optimal treatment could lower the prevalence of PHN.  \nMethods: We collected 50 elderly acute HZO patients treated with short-term peripheral nerve stimulation (PNS) or supraorbital nerve pulsed radiofrequency (PRF) from three hospitals from October 2022 to October 2023. All patients completed 12-month follow-up. The Visual Analog Scale (VAS), Barrow Neurological Institute (BNI) score and Pittsburgh Sleep Quality Index (PSQI) were used to assess the pain intensity and sleep quality.  \nResults: The pain intensity and sleep quality of all patients was significantly relieved after surgery. Following surgery, the PNS group’s VAS and PSQI scores were statistically lower than those of the PRF group, and they also took less medication. At 3 months after surgery, the incidence of clinically significant PHN in the PNS group was lower than the PNS group. At 12 months after surgery, the BNI scores of the PNS group were better than the PRF group.  \nReceived August 13, 2025; Revised September 17, 2025; Accepted September 30, 2025 Handling Editor: Younghoon Jeon  \nCorrespondence: Xintian Cao  \nPain Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, 461 Bayi Blvd, Donghu District, Nanchang, Jiangxi, China 330006, China  \nTel: +86-0791-88692578, [E-mail:](E-mail: cxtian0816@163.com)[ cxtian0816@163.com](E-mail: cxtian0816@163.com)  \nChangxi Li  \nPain Medicine, GuiQian International General Hospital, 1 Dongfeng Da Dao, Wudang District, Guiyang City, Guizhou Province 550018, China  \nTel: +86-0851-86277666, [E-mail:](E-mail: yanjicharlie66@126.com)[ yanjicharlie66@126.com](E-mail: yanjicharlie66@126.com)  \nYong Zhang  \nPain Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, 461 Bayi Blvd, Donghu District, Nanchang, Jiangxi, China 330006, China  \nTel: +86-0791-88692578, [E-mail:](E-mail: zy830226@163.com)[ zy830226@163.com](E-mail: zy830226@163.com)  \n*Dr. Yi Yan and Zhiwei Wu contributed equally to this work.  \nThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ([https://creativecommons.org/](https://creativecommons.org/)[ ](https://creativecommons.org/)[licenses/by-nc/4.0](licenses/by-nc/4.0)), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.  \nCopyright © The Korean Pain Society  \nABSTRACT  \nConclusions: Early application of short-term PNS or PRF for acute-phase HZO in the elderly can relieve pain. Compared to PRF, PNS may offer superior pain management, enhance quality of life, and contribute to a downward trend in the incidence of PHN.  \nKeywords: Electric Stimulation Therapy; Herpes Zoster Ophthalmicus; Neuralgia, Postherpetic; Pain Management; Pain Measurement; Pulsed Radiofrequency Treatment; Visual A","cbCaiowpW4jf0LyQ","https://ap.wps.com/l/cbCaiowpW4jf0LyQ","pdf",1457401,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusions\n# Introduction\n## Clinical challenge of PHN after HZ\n## Specific features of HZO","[{\"question\":\"What clinical problem does the study address in elderly patients?\",\"answer\":\"Elderly patients with herpes zoster ophthalmicus (HZO) have a high risk of progressing to postherpetic neuralgia (PHN). The study focuses on early interventions to reduce PHN occurrence and improve outcomes.\"},{\"question\":\"How were patients treated and what follow-up duration was used?\",\"answer\":\"Fifty elderly patients with acute HZO received short-term peripheral nerve stimulation (PNS) or supraorbital nerve pulsed radiofrequency (PRF). All patients completed a 12-month follow-up period.\"},{\"question\":\"Which assessment tools were used to evaluate outcomes?\",\"answer\":\"Pain intensity and sleep quality were evaluated using the Visual Analog Scale (VAS) and Pittsburgh Sleep Quality Index (PSQI). Neurologic outcomes were assessed using Barrow Neurological Institute (BNI) scores.\"}]","Short-term peripheral nerve stimulation or pulsed radiofrequency in elderly patients with acute herpes zoster ophthalmicus - multi-center retrospective study | PDF",1790665543,23]