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Methods: Patients with non-sex-specific solid invasive cancers diagnosed between January 2018 and December 2019 were included, covering 98.8% of the population, with outcomes assessed by sex. Results: Women were more likely to undergo cancer surgery, while men showed higher 90-day reoperation and mortality overall, with an exception for bladder cancer. Conclusion: Findings support improved gender equality in access and outcomes for oncological surgical care.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/sex-related-differences-in-oncological-surgery-and-postoperative-outcomes-comprehensive-nationwide-study-in-france/339917/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/sex-related-differences-in-oncological-surgery-and-postoperative-outcomes-comprehensive-nationwide-study-in-france/339917.png","ImageObject",300,407,{"name":92,"@type":93},"Asher","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-22","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the main objective of the study?","Question",{"text":112,"@type":113},"To investigate sex-related differences in cancer surgery and postoperative outcomes using nationwide observational data.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were postoperative reoperation and mortality outcomes measured?",{"text":117,"@type":113},"Outcomes were assessed by sex as the likelihood of surgery plus type of oncological surgery, with 30-, 60-, and 90-day reoperation and mortality rates.",{"name":119,"@type":110,"acceptedAnswer":120},"What key difference in outcomes emerged between men and women?",{"text":121,"@type":113},"Women were more likely to undergo cancer surgery, but men had higher 90-day reoperation and mortality overall, except for bladder cancer where women had higher 90-day mortality.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},339917,1790077729,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},687197207639,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","BJS, 2024, znae179  \n[https://doi.org/10.1093/bjs/znae179](https://doi.org/10.1093/bjs/znae179)  \nOriginal Article  \nSex-related differences in oncological surgery and postoperative outcomes: comprehensive, nationwide study in France  \nFloriane Jochum1,2 , Anne-Sophie Hamy1,3 , Paul Gougis1, Élise Dumas1, Beatriz Grandal1,4, Mathilde Sauzey1,4, Enora Laas4, Jean-Guillaume Feron4, Virginie Fourchotte4, Thomas Gaillard4, Noemie Girard4, Lea Pauly4, Elodie Gauroy4, Lauren Darrigues4, Judicael Hotton5, Lise Lecointre2, Fabien Reyal1,4,* , Fabrice Lecuru4 and CherifAkladios2  \n1Residual Tumour and Response to Treatment Laboratory, RT2Lab, Translational Research Department, INSERM, U932 Immunity and Cancer, Paris, France 2Department of Gynaecology, Strasbourg University Hospital, Strasbourg, France  \n3Department of Medical Oncology, Institut Curie, Université Paris Cité, Paris, France  \n4Department of Breast and Gynaecological Surgery, Institut Curie, Paris, Université Paris Cité, Paris, France 5Department of Surgical Oncology, Institut Godinot, Reims, France  \n*Correspondence to: Fabien Reyal, RT2lab, Institut Curie, 26 Rue d’Ulm, 75005 Paris, France (e-mail: [fabien.reyal@gmail.com](fabien.reyal@gmail.com))  \nAbstract  \nBackground: The main objective of this study was to undertake an exhaustive investigation of sex-related differences in cancer surgery.  \nMethods: This observational study used data from the French national health insurance system database covering 98.8% of the population. Patients diagnosed with non-sex-specific solid invasive cancers between January 2018 and December 2019 were included. The main outcomes were likelihood of undergoing cancer surgery, type of oncological surgery performed, and associated 30- , 60- , and 90-day postoperative reoperation and mortality rates, by sex.  \nResults: For the 367 887 patients included, women were 44% more likely than men to undergo cancer surgery (OR 1.44, 95% c.i. 1.31 to 1.59; P \u003C 0.001). However, the likelihood of surgery decreased with advancing age (OR 0.98, 0.98 to 0.98; P \u003C 0.001), and with increasing number of co-morbid conditions (OR 0.95, 0.95 to 0.96; P \u003C 0.001), especially in women. Men had higher 90-day reoperation (21.2 versus 18.8%; P \u003C 0.001) and mortality (1.2 versus 0.9%; P \u003C 0.001) rates than women, overall, and for most cancer types, with the exception of bladder cancer, for which the 90-day mortality rate was higher among women (1.8 versus 1.4%; P \u003C 0.001) . After adjustment for age, number of co-morbid conditions, and surgical procedure, 90-day mortality remained higher in men (OR 1.16, 1.07 to 1.26; P \u003C 0.001), and men were 21% more likely than women to undergo reoperation within 90 days (OR 1.21, 1.18 to 1.23; P \u003C 0.001) .  \nConclusion: Women were much more likely than men to undergo cancer surgery than men, but the likelihood of surgery decreased with advancing age and with increasing number of co-morbid conditions, especially in women. These findings highlight a need for both increased awareness and strategies to ensure gender equality in access to oncological surgical treatment and improved outcomes.  \nIntroduction  \nSex and gender are two distinct concepts in healthcare. Sex is based on biological factors, whereas gender is tied to societal roles, behaviours, and life experiences1. Gender differences play a crucial role in shaping healthcare experiences, including access to care, healthcare system use, and the attitudes of medical staff2. Prevailing gender differences in healthcare encapsulate disparities in access to preventive medicine, drug-prescribing  \npatterns, and referral for, or acceptance of, surgical treatments.  \nIn oncology, there is evidence to suggest that men and women may not always receive identical treatments, even when clinically recommended. For example, women diagnosed with head-and-neck3 , bladder4, gastro-oesophageal5 ,6 or colorectal cancers7 are less likely to undergo intensive chemoradiotherapy than men. These disparitie","cbCaip42sxVSBlRN","https://ap.wps.com/l/cbCaip42sxVSBlRN","pdf",272871,11,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusion\n# Introduction","[{\"question\":\"What was the main objective of the study?\",\"answer\":\"To investigate sex-related differences in cancer surgery and postoperative outcomes using nationwide observational data.\"},{\"question\":\"How were postoperative reoperation and mortality outcomes measured?\",\"answer\":\"Outcomes were assessed by sex as the likelihood of surgery plus type of oncological surgery, with 30-, 60-, and 90-day reoperation and mortality rates.\"},{\"question\":\"What key difference in outcomes emerged between men and women?\",\"answer\":\"Women were more likely to undergo cancer surgery, but men had higher 90-day reoperation and mortality overall, except for bladder cancer where women had higher 90-day mortality.\"}]","Sex-related differences in oncological surgery and postoperative outcomes: comprehensive, nationwide study in France | PDF",1790033077,28]