[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-128390-en":3,"doc-seo-128390-105":30,"detail-sidebar-cat-0-en-105":92},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":20,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":27,"seo_description":14,"update_tm":28,"read_time":29},128390,962085564807,"Aurelia","https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8",7,"Healthcare","Serum Amyloid-A to High-Density Lipoprotein Cholesterol Ratio as a Superior Biomarker for Early Diagnosis","The study evaluates whether the serum amyloid-A to high-density lipoprotein cholesterol ratio (A/H) can serve as a superior biomarker for early diagnosis, focusing on diagnostic performance in Alzheimer’s disease. Statistical analyses and model comparisons investigate associations between A/H and clinical outcomes, including sensitivity, specificity, and receiver operating characteristics. Results indicate that A/H adds discriminative value over individual markers and composite inflammatory indices, supporting its potential utility for earlier identification in AD.","TYPE O􀀂􀀉􀀘􀀉􀀎􀀆􀀝 􀀞􀀃􀀋􀀃􀀆􀀂􀀕􀀅 PUB􀀕I􀀁􀀏E􀀒 30 J􀀆􀀎􀀔􀀆􀀂􀀐 2026  \n􀀒OI 10.3389/􀀒􀀕􀀏m.2026.1719851  \n􀀁􀀂􀀃􀀄􀀁􀀂 􀀆􀀇  \n􀀁􀀂􀀃􀀃􀀄􀀅􀀆 􀀈􀀅􀀂􀀉􀀊􀀆􀀋􀀌  \n􀀍􀀎􀀉􀀏􀀃􀀂􀀋􀀉􀀄􀀐 􀀑􀀒 􀀓􀀃􀀎􀀄􀀔􀀕􀀖􀀐􀀌 􀀍􀀎􀀉􀀄􀀃􀀊 􀀈􀀄􀀆􀀄􀀃􀀋  \n􀀈􀀁􀀉􀀃􀀁􀀊􀀁􀀂 􀀆􀀇  \n􀀗􀀉􀀆􀀑􀀕􀀅􀀆􀀎􀀘 􀀙􀀃􀀎􀀘􀀌􀀚􀀆􀀎􀀕􀀅􀀆􀀎􀀘 􀀍􀀎􀀉􀀏􀀃􀀂􀀋􀀉􀀄􀀐􀀌 􀀛􀀅􀀉􀀎􀀆􀀜􀀑􀀝􀀒􀀘􀀆􀀎􀀘 􀀞􀀑􀀄􀀄 􀀆􀀔􀀃􀀂􀀌  \n􀀍􀀝m 􀀍􀀎􀀉􀀏􀀃􀀂􀀋􀀉􀀄􀀐 M􀀃􀀊􀀉􀀕􀀆􀀝 􀀛􀀃􀀎􀀄􀀃􀀂􀀌 G􀀃􀀂m􀀆􀀎􀀐  \n*􀀋􀀌􀀈􀀈􀀁􀀍􀀎􀀌􀀏􀀂􀀁􀀏􀀋􀀁  \nJ􀀔􀀎 M􀀆  \n 15822331568@163 .􀀕􀀑m †T􀀅􀀃􀀋􀀃 􀀆􀀔􀀄􀀅􀀑􀀂􀀋 􀀅􀀆􀀏􀀃 􀀕􀀑􀀎􀀄􀀂􀀉 􀀔􀀄􀀃􀀊 􀀃q􀀔􀀆􀀝􀀝􀀐 􀀄􀀑􀀄􀀅􀀉􀀋 w􀀑􀀂􀀖  \n􀀈􀀁􀀋􀀁􀀃􀀉􀀁􀀂 08 O􀀕􀀄􀀑 􀀃􀀂 2025  \n􀀈􀀁􀀉􀀃􀀍􀀁􀀂 25 D􀀃􀀕􀀃m 􀀃􀀂 2025  \n􀀐􀀋􀀋􀀁􀀎􀀄􀀁􀀂 12 J􀀆􀀎􀀔􀀆􀀂􀀐 2026  \n􀀎􀀑􀀆􀀒􀀃􀀍􀀓􀀁􀀂 30 J􀀆􀀎􀀔􀀆􀀂􀀐 2026  \n􀀋􀀃􀀄􀀐􀀄􀀃􀀌􀀏  \n􀀜􀀆􀀎􀀘 Z􀀌 􀀜􀀆􀀎􀀘 􀀗􀀌 􀀛􀀆􀀉 Y􀀌 Z􀀅􀀆􀀎􀀘 A􀀌 􀀜􀀆􀀎􀀘 Y􀀌 H􀀔 􀀙􀀌 G􀀔􀀑 Y 􀀆􀀎􀀊 M􀀆 J (2026) 􀀈􀀃􀀂􀀔m-Am􀀐􀀝􀀑􀀉􀀊 -A 􀀄􀀑 H􀀉􀀘􀀅-D􀀃􀀎􀀋􀀉􀀄􀀐-􀀙􀀉p􀀑p􀀂􀀑􀀄􀀃􀀉􀀎-􀀛􀀅􀀑􀀝􀀃􀀋􀀄􀀃􀀂􀀑􀀝􀀞􀀆􀀄􀀉􀀑: 􀀋􀀔p􀀃􀀂􀀉􀀑􀀂 􀀉􀀑m􀀆􀀂􀀖􀀃􀀂 􀀒􀀑􀀂 􀀃􀀆􀀂􀀝􀀐 􀀊􀀉􀀆􀀘􀀎􀀑􀀋􀀉􀀋􀀑􀀒 􀀕􀀑􀀂􀀑􀀎􀀆􀀂􀀐 􀀆􀀂􀀄􀀃􀀂􀀐 􀀊􀀉􀀋􀀃􀀆􀀋􀀃 w􀀉􀀄􀀅 􀀕􀀝􀀉􀀎􀀉􀀕􀀆􀀝􀀝􀀐􀀂􀀃􀀝􀀃􀀏􀀆􀀎􀀄 􀀋􀀄􀀃􀀎􀀑􀀋􀀃􀀋 􀀆􀀎􀀊 􀀊􀀃􀀏􀀃􀀝􀀑pm􀀃􀀎􀀄 􀀑􀀒 m􀀆􀀕􀀅􀀉􀀎􀀃 􀀝􀀃􀀆􀀂􀀎􀀉􀀎􀀘 􀀊􀀉􀀆􀀘􀀎􀀑􀀋􀀄􀀉􀀕 m􀀑􀀊􀀃􀀝 .  \nF􀀂􀀑􀀎􀀄 . 􀀛􀀆􀀂􀀊􀀉􀀑􀀏􀀆􀀋􀀕 . M􀀃􀀊 . 13:1719851 .􀀊􀀑􀀉: 10.3389/􀀒􀀕􀀏m.2026.1719851  \n􀀋􀀌􀀎􀀇􀀈􀀃􀀔􀀓􀀄  \n© 2026 􀀜􀀆􀀎􀀘􀀌 􀀜􀀆􀀎􀀘􀀌 􀀛􀀆􀀉􀀌 Z􀀅􀀆􀀎􀀘􀀌 􀀜􀀆􀀎􀀘􀀌 H􀀔􀀌 G􀀔􀀑 􀀆􀀎􀀊 M􀀆 . T􀀅􀀉􀀋 􀀉􀀋 􀀆􀀎 􀀑p􀀃􀀎-􀀆􀀕􀀕􀀃􀀋􀀋 􀀆􀀂􀀄􀀉􀀕􀀝􀀃􀀊􀀉􀀋􀀄􀀂􀀉 􀀔􀀄􀀃􀀊 􀀔􀀎􀀊􀀃􀀂 􀀄􀀅􀀃 􀀄􀀃􀀂m􀀋 􀀑􀀒 􀀄􀀅􀀃 􀀛􀀂􀀃􀀆􀀄􀀉􀀏􀀃􀀛􀀑mm􀀑􀀎􀀋 A􀀄􀀄􀀂􀀉 􀀔􀀄􀀉􀀑􀀎 􀀙􀀉􀀕􀀃􀀎􀀋􀀃 (􀀛􀀛 BY) . T􀀅􀀃􀀔􀀋􀀃􀀌 􀀊􀀉􀀋􀀄􀀂􀀉 􀀔􀀄􀀉􀀑􀀎 􀀑􀀂 􀀂􀀃p􀀂􀀑􀀊􀀔􀀕􀀄􀀉􀀑􀀎 􀀉􀀎 􀀑􀀄􀀅􀀃􀀂􀀒􀀑􀀂􀀔m􀀋 􀀉􀀋 p􀀃􀀂m􀀉􀀄􀀄􀀃􀀊􀀌 p􀀂􀀑􀀏􀀉􀀊􀀃􀀊 􀀄􀀅􀀃 􀀑􀀂􀀉􀀘􀀉􀀎􀀆􀀝􀀆􀀔􀀄􀀅􀀑􀀂(􀀋) 􀀆􀀎􀀊 􀀄􀀅􀀃 􀀕􀀑p􀀐􀀂􀀉􀀘􀀅􀀄 􀀑w􀀎􀀃􀀂(􀀋) 􀀆􀀂􀀃􀀕􀀂􀀃􀀊􀀉􀀄􀀃􀀊 􀀆􀀎􀀊 􀀄􀀅􀀆􀀄 􀀄􀀅􀀃 􀀑􀀂􀀉􀀘􀀉􀀎􀀆􀀝 p􀀔 􀀝􀀉􀀕􀀆􀀄􀀉􀀑􀀎 􀀉􀀎􀀄􀀅􀀉􀀋 j􀀑􀀔􀀂􀀎􀀆􀀝 􀀉􀀋 􀀕􀀉􀀄􀀃􀀊􀀌 􀀉􀀎 􀀆􀀕􀀕􀀑􀀂􀀊􀀆􀀎􀀕􀀃 w􀀉􀀄􀀅  \n􀀆􀀕􀀕􀀃p􀀄􀀃􀀊 􀀆􀀕􀀆􀀊􀀃m􀀉􀀕 p􀀂􀀆􀀕􀀄􀀉􀀕􀀃 . 􀀚􀀑 􀀔􀀋􀀃􀀌􀀊􀀉􀀋􀀄􀀂􀀉 􀀔􀀄􀀉􀀑􀀎 􀀑􀀂 􀀂􀀃p􀀂􀀑􀀊􀀔􀀕􀀄􀀉􀀑􀀎 􀀉􀀋 p􀀃􀀂m􀀉􀀄􀀄􀀃􀀊 w􀀅􀀉􀀕􀀅 􀀊􀀑􀀃􀀋 􀀎􀀑􀀄 􀀕􀀑mp􀀝􀀐 w􀀉􀀄􀀅 􀀄􀀅􀀃􀀋􀀃 􀀄􀀃􀀂m􀀋 .  \n􀀁􀀂􀀃􀀄􀀅􀀆􀀇􀀅􀀈􀀉􀀊􀀋􀀌􀀆􀀇 􀀎􀀊 􀀏􀀋􀀐􀀑􀀆􀀒􀀂􀀓􀀔􀀋􀀎􀀈􀀆􀀕􀀋􀀖􀀊􀀖􀀃􀀊􀀎􀀂􀀋􀀓􀀆􀀗􀀑􀀊􀀉􀀂􀀔􀀎􀀂􀀃􀀊􀀉􀀘􀀙􀀎􀀋􀀊􀀚 􀀔􀀄􀀖􀀂􀀃􀀋􀀊􀀃 􀀛􀀋􀀊􀀅􀀙􀀃􀀜􀀂􀀃 􀀝􀀊􀀃􀀂􀀙􀀃􀀉􀀈 􀀌􀀋􀀙􀀐􀀓􀀊􀀔􀀋􀀔 􀀊􀀝 􀀞􀀊􀀃􀀊􀀓􀀙􀀃􀀈 􀀙􀀃􀀎􀀂􀀃􀀈􀀌􀀋􀀔􀀂􀀙􀀔􀀂 􀀋􀀎􀀑 􀀞􀀉􀀋􀀓􀀋􀀞􀀙􀀉􀀉􀀈 􀀃􀀂􀀉􀀂v􀀙􀀓􀀎􀀔􀀎􀀂􀀓􀀊􀀔􀀂􀀔 􀀙􀀓􀀌 􀀌􀀂v􀀂􀀉􀀊􀀖􀀅􀀂􀀓􀀎 􀀊􀀝􀀅􀀙􀀞􀀑􀀋􀀓􀀂 􀀉􀀂􀀙􀀃􀀓􀀋􀀓􀀐 􀀌􀀋􀀙􀀐􀀓􀀊􀀔􀀎􀀋􀀞􀀅􀀊􀀌􀀂􀀉  \nZ􀀊􀀓􀀐z􀀂 W􀀙􀀓􀀐 1†, X􀀄􀀂􀀞􀀑􀀂􀀓 W􀀙􀀓􀀐 2†, Y􀀄􀀙􀀓􀀐 􀀗􀀙􀀋 2†, 􀀇􀀋􀀅􀀋􀀓 Z􀀑􀀙􀀓􀀐 1, Y􀀙􀀓􀀉􀀋 W􀀙􀀓􀀐 1, 􀀕􀀋j􀀄􀀙􀀓 􀀏􀀄 1, Y􀀄 G􀀄􀀊1 􀀙􀀓􀀌 J􀀄􀀓 M􀀙 1*   \n1 D􀀃p􀀆􀀂􀀄m􀀃􀀎􀀄 􀀑􀀒 M􀀃􀀊􀀉􀀕􀀆􀀝 􀀙􀀆 􀀑􀀂􀀆􀀄􀀑􀀂􀀐􀀌 T􀀉􀀆􀀎j􀀉􀀎 H􀀑􀀋p􀀉􀀄􀀆􀀝 􀀑􀀒 IT􀀛􀀜M 􀀚􀀆􀀎􀀖􀀆􀀉 H􀀑􀀋p􀀉􀀄􀀆􀀝􀀌 T􀀉􀀆􀀎j􀀉􀀎􀀌 􀀛􀀅􀀉􀀎􀀆􀀌 2􀀈􀀕􀀅􀀑􀀑􀀝􀀑􀀒 M􀀃􀀊􀀉􀀕􀀉􀀎􀀃􀀌 􀀚􀀆􀀎􀀖􀀆􀀉 􀀍􀀎􀀉􀀏􀀃􀀂􀀋􀀉􀀄􀀐􀀌 T􀀉􀀆􀀎j􀀉􀀎􀀌 􀀛􀀅􀀉􀀎􀀆  \n􀀆􀀕􀀖􀀗􀀘􀀙􀀚􀀛􀀜􀀝􀀞 T􀀅􀀉􀀋 􀀋􀀄􀀔􀀊􀀐 􀀆􀀉m􀀃􀀊 􀀄􀀑 􀀃􀀏􀀆􀀝􀀔􀀆􀀄􀀃 􀀄􀀅􀀃 􀀃􀀆􀀂􀀝􀀐 􀀊􀀉􀀆􀀘􀀎􀀑􀀋􀀄􀀉􀀕 􀀏􀀆􀀝􀀔􀀃 􀀑􀀒 􀀈􀀃􀀂􀀔mAm􀀐􀀝􀀑􀀉􀀊-A 􀀄􀀑 H􀀉􀀘􀀅-D􀀃􀀎􀀋􀀉􀀄􀀐-􀀙􀀉p􀀑p􀀂􀀑􀀄􀀃􀀉􀀎-􀀛􀀅􀀑􀀝􀀃􀀋􀀄􀀃􀀂􀀑􀀝 􀀞􀀆􀀄􀀉􀀑 (􀀈H􀀞) 􀀒􀀑􀀂 􀀕􀀑􀀂􀀑􀀎􀀆􀀂􀀐􀀆􀀂􀀄􀀃􀀂􀀐 􀀊􀀉􀀋􀀃􀀆􀀋􀀃 (􀀛AD) w􀀉􀀄􀀅 􀀕􀀝􀀉􀀎􀀉􀀕􀀆􀀝􀀝􀀐 􀀂􀀃􀀝􀀃􀀏􀀆􀀎􀀄 􀀋􀀄􀀃􀀎􀀑􀀋􀀃􀀋 􀀆􀀎􀀊 􀀊􀀃􀀏􀀃􀀝􀀑p 􀀆 m􀀆􀀕􀀅􀀉􀀎􀀃􀀝􀀃􀀆􀀂􀀎􀀉􀀎􀀘 􀀊􀀉􀀆􀀘􀀎􀀑􀀋􀀄􀀉􀀕 m􀀑􀀊􀀃􀀝 􀀆􀀋􀀃􀀊 􀀑􀀎 􀀃􀀗􀀄􀀂􀀃m􀀃 G􀀂􀀆􀀊􀀉􀀃􀀎􀀄 B􀀑􀀑􀀋􀀄􀀉􀀎􀀘 (􀀗GB􀀑􀀑􀀋􀀄) .  \neth􀀚􀀝s 􀀕􀀜􀀝 􀀙es􀀛lts􀀞 D􀀆􀀄􀀆 􀀒􀀂􀀑m 1􀀌108 􀀛AD p􀀆􀀄􀀉􀀃􀀎􀀄􀀋 (w􀀉􀀄􀀅 􀀕􀀑􀀂􀀑􀀎􀀆􀀂􀀐 􀀝􀀔m􀀉􀀎􀀆􀀝􀀊􀀉􀀆m􀀃􀀄􀀃􀀂 􀀋􀀄􀀃􀀎􀀑􀀋􀀉􀀋 ≥50% 􀀑􀀂 􀀃􀀏􀀉􀀊􀀃􀀎􀀕􀀃 􀀑􀀒 􀀒􀀔􀀎􀀕􀀄􀀉􀀑􀀎􀀆􀀝 m􀀐􀀑􀀕􀀆􀀂􀀊􀀉􀀆􀀝 􀀉􀀋􀀕􀀅􀀃m􀀉􀀆) 􀀆􀀎􀀊 962 􀀕􀀑􀀎􀀄􀀂􀀑􀀝􀀋 w􀀃􀀂􀀃 􀀂􀀃􀀄􀀂􀀑􀀋p􀀃􀀕􀀄􀀉􀀏􀀃􀀝􀀐 􀀆􀀎􀀆􀀝􀀐z􀀃􀀊 . 􀀞􀀃􀀕􀀃􀀉􀀏􀀃􀀂 􀀑p􀀃􀀂􀀆􀀄􀀉􀀎􀀘 􀀕􀀅􀀆􀀂􀀆􀀕􀀄􀀃􀀂􀀉􀀋􀀄􀀉􀀕(􀀞O􀀛) 􀀆􀀎􀀆􀀝􀀐􀀋􀀉􀀋 􀀋􀀅􀀑w􀀃􀀊 􀀈H􀀞 (􀀆􀀂􀀃􀀆 􀀔􀀎􀀊􀀃􀀂 􀀄􀀅􀀃 􀀕􀀔􀀂􀀏􀀃 (A􀀍􀀛) = 0.769)􀀑􀀔􀀄p􀀃􀀂􀀒􀀑􀀂m􀀃􀀊 􀀛-􀀂􀀃􀀆􀀕􀀄􀀉􀀏􀀃 p􀀂􀀑􀀄􀀃􀀉􀀎 (􀀛􀀞􀀁) ( 􀀁 = 0 . 006) 􀀆􀀎􀀊 􀀈􀀃􀀂􀀔m 􀀆m􀀐􀀝􀀑􀀉􀀊 A (􀀈AA) ( 􀀁 \u003C 0 . 001) . F􀀑􀀔􀀂 􀀗GB􀀑􀀑􀀋􀀄 m􀀑􀀊􀀃􀀝􀀋 w􀀃􀀂􀀃 􀀕􀀑􀀎􀀋􀀄􀀂􀀔􀀕􀀄􀀃􀀊􀀌 􀀆􀀎􀀊 􀀄􀀅􀀃 􀀃􀀋􀀄 m􀀑􀀊􀀃􀀝 (􀀛􀀞􀀁 + 􀀈AA + 􀀈H􀀞 + 13 􀀑􀀄􀀅􀀃􀀂 􀀏􀀆􀀂􀀉􀀆 􀀝􀀃􀀋) 􀀆􀀕􀀅􀀉􀀃􀀏􀀃􀀊 􀀆􀀎 A􀀍􀀛 􀀑􀀒 0 .876. 􀀈H􀀞􀀕􀀑􀀂􀀂􀀃􀀝􀀆􀀄􀀃􀀊 􀀎􀀑􀀎􀀝􀀉􀀎􀀃􀀆􀀂􀀝􀀐 w􀀉􀀄􀀅 􀀆􀀘􀀃 ( 􀀁 \u003C 0 . 001)􀀌 􀀆􀀎􀀊 􀀉􀀄􀀋 􀀊􀀉􀀆􀀘􀀎􀀑􀀋􀀄􀀉􀀕 􀀃􀀒fi􀀕􀀆􀀕􀀐 w􀀆􀀋􀀅􀀉􀀘􀀅􀀃􀀂 􀀉􀀎 􀀐􀀑􀀔􀀎􀀘􀀃􀀂 p􀀆􀀄􀀉􀀃􀀎􀀄􀀋 (40 􀀐􀀃􀀆􀀂􀀋 􀀑􀀝􀀊􀀌 O􀀞 = 16.29) 􀀄􀀅􀀆􀀎 􀀉􀀎 􀀑􀀝􀀊􀀃􀀂 􀀆􀀊􀀔􀀝􀀄􀀋 (80 􀀐􀀃􀀆􀀂􀀋 􀀑􀀝􀀊􀀌 O􀀞 = 4 .37) . M􀀆􀀕􀀅􀀉􀀎􀀃 􀀝􀀃􀀆􀀂􀀎􀀉􀀎􀀘 m􀀑􀀊􀀃􀀝􀀋 􀀕􀀆􀀎 􀀆􀀊􀀊􀀂􀀃􀀋􀀋 􀀄􀀅􀀃 􀀊􀀃􀀕􀀝􀀉􀀎􀀃 􀀉􀀎􀀊􀀉􀀆􀀘􀀎􀀑􀀋􀀄􀀉􀀕 􀀕􀀆p􀀆 􀀉􀀝􀀉􀀄􀀐 􀀑􀀒 􀀈H􀀞 􀀉􀀎 􀀄􀀅􀀃 􀀃􀀝􀀊􀀃􀀂􀀝􀀐 p􀀑p􀀔􀀝􀀆􀀄􀀉􀀑􀀎 .  \n􀀋􀀚􀀜􀀖l􀀛si􀀚􀀜􀀞 􀀈H􀀞 􀀉􀀋 􀀆 􀀋􀀔p􀀃􀀂􀀉􀀑􀀂 􀀕􀀑mp􀀑􀀋􀀉􀀄􀀃 􀀉􀀑m􀀆􀀂􀀖􀀃􀀂 􀀒􀀑􀀂 􀀃􀀆􀀂􀀝􀀐 􀀊􀀉􀀆􀀘􀀎􀀑􀀋􀀉􀀋 􀀑􀀒 􀀛AD w􀀉􀀄􀀅 􀀕􀀝􀀉􀀎􀀉􀀕􀀆􀀝􀀝􀀐 􀀂􀀃􀀝􀀃􀀏􀀆􀀎􀀄 􀀋􀀄􀀃􀀎􀀑􀀋􀀃􀀋􀀌 􀀑􀀔􀀄p􀀃􀀂􀀒􀀑􀀂m􀀉􀀎􀀘 􀀛􀀞􀀁 􀀆􀀎􀀊 􀀈AA. M􀀆􀀕􀀅􀀉􀀎􀀃 􀀝􀀃􀀆􀀂􀀎􀀉􀀎􀀘 m􀀑􀀊􀀃􀀝 􀀉􀀎􀀄􀀃􀀘􀀂􀀆􀀄􀀉􀀎􀀘 m􀀔􀀝􀀄􀀉p􀀝􀀃 􀀉􀀎􀀊􀀉􀀕􀀆􀀄􀀑􀀂􀀋 􀀋􀀅􀀑w􀀋 􀀃x􀀕􀀃􀀝􀀝􀀃􀀎􀀄 􀀊􀀉􀀆􀀘􀀎􀀑􀀋􀀄􀀉􀀕 p􀀃􀀂􀀒􀀑􀀂m􀀆􀀎􀀕􀀃 . E􀀝􀀃􀀏􀀆􀀄􀀃􀀊 􀀈H􀀞 􀀉􀀎􀀊􀀉􀀕􀀆􀀄􀀃􀀋 􀀅􀀉􀀘􀀅􀀃􀀂 􀀛AD 􀀂􀀉􀀋􀀖 􀀉􀀎 􀀐􀀑􀀔􀀎􀀘􀀃􀀂 􀀉􀀎􀀊􀀉􀀏􀀉􀀊􀀔􀀆􀀝􀀋􀀌 p􀀂􀀑􀀏􀀉􀀊􀀉􀀎􀀘 􀀆 􀀎􀀃w 􀀋􀀄􀀂􀀆􀀄􀀃􀀘􀀐 􀀒􀀑􀀂 􀀃􀀆􀀂􀀝􀀐 􀀋􀀕􀀂􀀃􀀃􀀎􀀉􀀎􀀘 􀀑􀀒 􀀛AD w􀀉􀀄􀀅 􀀕􀀝􀀉􀀎􀀉􀀕􀀆􀀝􀀝􀀐 􀀂􀀃􀀝􀀃􀀏􀀆􀀎􀀄 􀀋􀀄􀀃􀀎􀀑􀀋􀀃􀀋 .  \nK􀀁􀀇􀀊􀀌􀀈􀀂􀀍  \n􀀖􀀚􀀙􀀚􀀜􀀕􀀙y 􀀕􀀙te􀀙y 􀀝ise􀀕se, 􀀋-􀀙e􀀕􀀖tive p􀀙􀀚tei􀀜, ext􀀙eme 􀀘􀀙􀀕􀀝ie􀀜t b􀀚􀀚sti􀀜􀀘, m􀀕􀀖hi􀀜ele􀀕􀀙􀀜i􀀜􀀘, se􀀙􀀛m 􀀕myl􀀚i􀀝 􀀐, 􀀍e􀀙􀀛m-􀀐myl􀀚i􀀝-􀀐 t􀀚 􀀓i􀀘h-􀀂e􀀜sity-􀀒ip􀀚p􀀙􀀚tei􀀜 -􀀋h􀀚leste􀀙􀀚l 􀀈􀀕ti􀀚  \nF􀀃􀀊􀀓􀀎􀀋􀀂􀀃􀀔 􀀋􀀓 􀀗􀀙􀀃􀀌􀀋􀀊v􀀙􀀔􀀞􀀄􀀉􀀙􀀃 M􀀂􀀌􀀋􀀞􀀋􀀓􀀂 01 􀀝􀀃􀀊􀀓􀀎􀀋􀀂􀀃􀀔􀀋􀀓 .􀀊􀀃􀀐  \n1 I􀀓􀀎􀀃􀀊􀀌􀀄􀀞􀀎􀀋􀀊􀀓  \n􀀁􀀂􀀃􀀂􀀄􀀅􀀃􀀆 􀀅􀀃􀀈􀀉􀀃􀀆 􀀊􀀋􀀌􀀉􀀅􀀌􀀉 􀀍􀀁􀀎􀀏􀀐 􀀑􀀂􀀄􀀈􀀋􀀄􀀒􀀉􀀌 􀀈􀀂 􀀓􀀉 􀀅 􀀔􀀅􀀕􀀂􀀃􀀑􀀂􀀄􀀈􀀃􀀋􀀓􀀒􀀈􀀂􀀃 􀀈􀀂 􀀖􀀗􀀂􀀓􀀅􀀗 􀀔􀀂􀀃􀀓􀀋􀀊􀀋􀀈􀀆 􀀅􀀄􀀊 􀀔􀀂􀀃􀀈􀀅􀀗􀀋􀀈􀀆 􀀍􀀘􀀐􀀙 􀀚􀀈􀀌 􀀛􀀃􀀉􀀜􀀅􀀗􀀉􀀄􀀑􀀉􀀌􀀝􀀂􀀞􀀌 􀀌􀀋􀀖􀀄􀀋 􀀑􀀅􀀄􀀈 􀀖􀀉􀀂􀀖􀀃􀀅􀀛􀀝􀀋􀀑􀀅􀀗 􀀜􀀅􀀃􀀋􀀅􀀓􀀋􀀗􀀋􀀈􀀆, 􀀞􀀋􀀈􀀝 􀀝􀀋􀀖􀀝􀀉􀀃 􀀅􀀖􀀉 -􀀌􀀈􀀅􀀄􀀊􀀅􀀃􀀊􀀋z􀀉􀀊 􀀋􀀄􀀑􀀋􀀊􀀉􀀄􀀑􀀉 􀀃􀀅􀀈􀀉􀀌 􀀂􀀓􀀌􀀉􀀃􀀜􀀉􀀊 􀀋􀀄 􀀗􀀂􀀞 - 􀀅􀀄􀀊 􀀔􀀋􀀊􀀊􀀗􀀉 -􀀋􀀄􀀑􀀂􀀔􀀉 􀀑􀀂􀀒􀀄􀀈􀀃􀀋􀀉􀀌 􀀈􀀝􀀅􀀄 􀀋􀀄 􀀝􀀋􀀖􀀝-􀀋􀀄􀀑􀀂􀀔􀀉 􀀄􀀅􀀈􀀋􀀂􀀄􀀌 􀀞􀀝􀀋􀀑􀀝 􀀃􀀉\\#􀀉􀀑􀀈􀀌􀀊􀀋􀀌􀀛􀀅􀀃􀀋􀀈􀀋􀀉􀀌 􀀋􀀄 􀀝􀀉􀀅􀀗􀀈􀀝􀀑􀀅􀀃􀀉 􀀅􀀑􀀑􀀉􀀌􀀌􀀋􀀓􀀋􀀗􀀋􀀈􀀆 􀀅􀀄􀀊 􀀃􀀋􀀌k f􀀅􀀑􀀈􀀂􀀃 􀀔􀀅􀀄􀀅􀀖􀀉􀀔􀀉􀀄􀀈􀀍2􀀐􀀙 􀀚􀀄 􀀈􀀝􀀉 U􀀄􀀋􀀈􀀉􀀊 S􀀈􀀅􀀈􀀉􀀌 􀀅􀀗􀀂􀀄􀀉, 􀀁􀀎􀀏 􀀅ff􀀉􀀑􀀈􀀌 7􀀙2% 􀀂f 􀀅","cbCaifcUmn60tJoI","https://ap.wps.com/l/cbCaifcUmn60tJoI","pdf",2602582,1,17,"English","en",105,"# Objectives and Biomarker Rationale\n## Serum A/H Ratio and Study Aim\n# Methods\n## Diagnostic Comparisons and Statistical Evaluation\n# Results\n## Discriminative Performance and Diagnostic Metrics\n# Discussion\n## Added Value and Clinical Implications","[{\"question\":\"What biomarker is evaluated for early diagnosis?\",\"answer\":\"The serum amyloid-A to high-density lipoprotein cholesterol ratio (A/H) is evaluated as a potential biomarker for early diagnosis in Alzheimer’s disease.\"},{\"question\":\"How is diagnostic performance assessed?\",\"answer\":\"Diagnostic performance is assessed using statistical comparisons of discrimination and metrics such as sensitivity/specificity and receiver operating characteristics.\"},{\"question\":\"Does the A/H ratio outperform other indicators?\",\"answer\":\"The findings indicate that the A/H ratio provides added discriminative value compared with individual markers and related inflammatory indices.\"}]","Serum Amyloid-A to High-Density Lipoprotein Cholesterol Ratio as a Superior Biomarker for Early Diagnosis | PDF",1785947243,43,{"code":4,"msg":31,"data":32},"ok",{"site_id":24,"language":23,"slug":33,"title":13,"keywords":34,"description":14,"schema_data":35,"social_meta":87,"head_meta":89,"extra_data":91,"updated_unix":28},"serum-amyloid-a-to-high-density-lipoprotein-cholesterol-ratio-as-a-superior-biomarker-for-early-diagnosis","",{"@graph":36,"@context":86},[37,54,69],{"@type":38,"itemListElement":39},"BreadcrumbList",[40,44,48,51],{"item":41,"name":42,"@type":43,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":45,"name":46,"@type":43,"position":47},"https://docshare.wps.com/document/","Document",2,{"item":49,"name":12,"@type":43,"position":50},"https://docshare.wps.com/document/healthcare/",3,{"item":52,"name":13,"@type":43,"position":53},"https://docshare.wps.com/document/serum-amyloid-a-to-high-density-lipoprotein-cholesterol-ratio-as-a-superior-biomarker-for-early-diagnosis/128390/",4,{"url":52,"name":13,"@type":55,"author":56,"headline":13,"publisher":58,"fileFormat":61,"inLanguage":23,"description":14,"dateModified":62,"datePublished":63,"encodingFormat":61,"isAccessibleForFree":64,"interactionStatistic":65},"DigitalDocument",{"name":9,"@type":57},"Person",{"url":41,"name":59,"@type":60},"DocShare","Organization","application/pdf","2026-08-23","2026-08-05",true,{"@type":66,"interactionType":67,"userInteractionCount":20},"InteractionCounter",{"@type":68},"ViewAction",{"@type":70,"mainEntity":71},"FAQPage",[72,78,82],{"name":73,"@type":74,"acceptedAnswer":75},"What biomarker is evaluated for early diagnosis?","Question",{"text":76,"@type":77},"The serum amyloid-A to high-density lipoprotein cholesterol ratio (A/H) is evaluated as a potential biomarker for early diagnosis in Alzheimer’s disease.","Answer",{"name":79,"@type":74,"acceptedAnswer":80},"How is diagnostic performance assessed?",{"text":81,"@type":77},"Diagnostic performance is assessed using statistical comparisons of discrimination and metrics such as sensitivity/specificity and receiver operating characteristics.",{"name":83,"@type":74,"acceptedAnswer":84},"Does the A/H ratio outperform other indicators?",{"text":85,"@type":77},"The findings indicate that the A/H ratio provides added discriminative value compared with individual markers and related inflammatory indices.","https://schema.org",{"og:url":52,"og:type":88,"og:title":13,"og:site_name":59,"og:description":14},"article",{"robots":90,"canonical":52},"index,follow",{"doc_id":7,"site_id":24},{"code":4,"msg":5,"data":93},[94,98,102,106,111,116,119,124,129,132,136],{"id":20,"doc_module":4,"doc_module_name":46,"category_name":95,"show_sort_weight":96,"slug":97},"Story & Novel",90,"story-novel",{"id":47,"doc_module":4,"doc_module_name":46,"category_name":99,"show_sort_weight":100,"slug":101},"Literature",80,"literature",{"id":53,"doc_module":4,"doc_module_name":46,"category_name":103,"show_sort_weight":104,"slug":105},"Exam",70,"exam",{"id":107,"doc_module":4,"doc_module_name":46,"category_name":108,"show_sort_weight":109,"slug":110},5,"Comic",60,"comic",{"id":112,"doc_module":4,"doc_module_name":46,"category_name":113,"show_sort_weight":114,"slug":115},6,"Technology",50,"technology",{"id":11,"doc_module":4,"doc_module_name":46,"category_name":12,"show_sort_weight":117,"slug":118},40,"healthcare",{"id":120,"doc_module":4,"doc_module_name":46,"category_name":121,"show_sort_weight":122,"slug":123},8,"Research & Report",30,"research-report",{"id":125,"doc_module":4,"doc_module_name":46,"category_name":126,"show_sort_weight":127,"slug":128},9,"Religion & Spirituality",20,"religion-spirituality",{"id":127,"doc_module":4,"doc_module_name":46,"category_name":130,"show_sort_weight":127,"slug":131},"World Cup","world-cup",{"id":133,"doc_module":4,"doc_module_name":46,"category_name":134,"show_sort_weight":133,"slug":135},10,"Lifestyle","lifestyle",{"id":137,"doc_module":4,"doc_module_name":46,"category_name":138,"show_sort_weight":107,"slug":139},19,"General","general"]