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A 38-year-old male presented with numerous reddish lesions on the lower and upper limbs and trunk, showing purpuric eruptions with brownish discoloration. Biopsy confirmed Schamberg’s disease. Oral anti-inflammatory therapy was given, leading to significant improvement after 3 months with no new lesions.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/schambergs-disease-a-rare-case-report-from-a-tertiary-care-hospital-in-gujarat/449822/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/schambergs-disease-a-rare-case-report-from-a-tertiary-care-hospital-in-gujarat/449822.png","ImageObject",300,407,{"name":92,"@type":93},"CatatanPagi","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-02","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What condition was confirmed by biopsy in the reported case?","Question",{"text":112,"@type":113},"A biopsy indicated Schamberg’s disease. Histopathology supported the diagnosis with epidermal changes and perivascular inflammation.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What were the patient’s main skin findings and distribution?",{"text":117,"@type":113},"The patient had numerous reddish lesions on the lower and upper limbs and the trunk, including purpuric eruptions with brownish discoloration and macules measuring about 1–2 cm.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the patient treated, and what was the follow-up outcome?",{"text":121,"@type":113},"The patient received oral anti-inflammatory drugs. After 3 months, existing lesions improved significantly and no new lesions developed.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},449822,1791340451,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":81,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":39,"preview_page_count":4},962090894170,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","Case Report  \nSchamberg’s Disease: A Rare Case Report from a Tertiary Care Hospital in Gujarat  \nAbstract  \nPigmented purpuric dermatoses (PPDs) comprise a collection of disorders characterized by many petechial hemorrhages due to underlying capillaritis. Specific clinical characteristics facilitate the categorization of PPD into different variants, with Schamberg’s disease being the most frequently encountered. Treatment may not always yield positive results, and recurrences are common. Wereport the case of a 38‑year‑old male patient who presented with numerous reddish lesions on his lower and upper limbs, as well as his trunk. He exhibited purpuric eruptions and brownish discolorations that were diffusely spread across these areas. A biopsy indicated Schamberg’s disease. The patient was treated with oral anti‑inflammatory drugs. After 3 months of follow‑up, there was significant improvement in the existing lesions, and no new lesions had developed.  \nKeywords: Capillaritis, pigmentation disorders, purpura, Schamberg’s disease   \nIntroduction  \nThe etiology of pigmented purpuric dermatoses (PPD) is uncertain. These diseases display a range of clinical presentations but share several histopathological similarities, including the extravasation of red blood cells (RBCs), hemosiderin deposits mainly found in dermal macrophages, constriction of small vessel lumens, endothelial swelling, anda lymphocytic infiltrate around the blood vessels.[1,2]  \nWhile PPD is predominantly found in the lower limbs of adults, it can also affect children. Distinct clinical characteristics facilitate the categorization of PPD into various variations, including Schamberg’s illness, pigmented purpuric lichenoid dermatitis of Gougerot–Blum, purpura annularis telangiectodes of Majocchi, eczematid‑like purpura of Doucas and Kapetanakis, and lichen aureus. There are instances when treatment does not yield the desired results, and recurrences can frequently happen.[3]  \nCase Report  \nA 38‑year‑old male, who was otherwise healthy, presented at our hospital with a variety of reddish lesions located on  \nThis is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License (CC BY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.  \nFor reprints [contact:](contact: WKHLRPMedknow_reprints@wolterskluwer.com)[ WKHLRPMedknow_reprints@wolterskluwer.com](contact: WKHLRPMedknow_reprints@wolterskluwer.com)  \nhis lower and upper limbs, as well as his trunk. These lesions had been developing over the past 3 months. There was no reported history of infection or prior medication use related to the skin issues. The lesions began to appear 3 months ago, increasing in number in a caudal‑cranial sequence, starting with the lower limbs and subsequently affecting the upper limbs and trunk. New lesions appeared following the older ones, which slowly began to fade. The patient had previously consulted an external facility and was treated with topical dexamethasone and oral vitamin C for 1 month, but this did not yield any improvement. During the examination, several macules and purpuric lesions were observed, measuring 1–2 cm in diameter, along with some erythematous‑violaceous and brownish lesions on the limbs and trunk [Figure 1] . Clinically, the patient was suspected to have cutaneous small vessel vasculitis, or Immunoglobulin A (IgA) vasculitis, or PPD.  \nA complete blood count (CBC) and peripheral smear (PS) examination were performed, revealing normal results. Coagulation screening tests and liver function tests (LFTs) also fell within the normal range. Tests for anti‑Hepatitis B Virus (HBV) and anti‑Hepatitis C Virus (HCV) antibodies returned negative  \nHow to cite this article: Ananda ni G, Goswami P, Madhudiya R, Bhankhodia V, Pathania YS. Schamberg’s disease: A rare cas","cbCaigTZGYljMsXK","https://ap.wps.com/l/cbCaigTZGYljMsXK","pdf",1169638,"English","# Abstract\n# Introduction\n# Case Report\n## Clinical presentation\n## Investigations\n## Biopsy and histopathology\n## Treatment and follow-up","[{\"question\":\"What condition was confirmed by biopsy in the reported case?\",\"answer\":\"A biopsy indicated Schamberg’s disease. Histopathology supported the diagnosis with epidermal changes and perivascular inflammation.\"},{\"question\":\"What were the patient’s main skin findings and distribution?\",\"answer\":\"The patient had numerous reddish lesions on the lower and upper limbs and the trunk, including purpuric eruptions with brownish discoloration and macules measuring about 1–2 cm.\"},{\"question\":\"How was the patient treated, and what was the follow-up outcome?\",\"answer\":\"The patient received oral anti-inflammatory drugs. After 3 months, existing lesions improved significantly and no new lesions developed.\"}]","Schamberg’s Disease - A Rare Case Report from a Tertiary Care Hospital in Gujarat | PDF",1790731148]