[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-460306-105":59,"doc-detail-460306-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","salivary-zinc-levels-in-rheumatoid-arthritis","Salivary Zinc Levels in Rheumatoid Arthritis","","Study evaluates and compares salivary zinc levels in individuals diagnosed with rheumatoid arthritis and healthy controls. Twenty participants were included after informed consent and divided into two equal groups: 10 healthy controls and 10 rheumatoid arthritis patients. Saliva samples were collected from all participants, and zinc concentrations were measured and analyzed for group differences. Results show higher mean salivary zinc in the rheumatoid arthritis group (83.52 ± 5.9 μg/dL) versus controls (69.56 ± 11.2 μg/dL).",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/salivary-zinc-levels-in-rheumatoid-arthritis/460306/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/salivary-zinc-levels-in-rheumatoid-arthritis/460306.png","ImageObject",300,407,{"name":92,"@type":93},"WPS_1790064749","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-08","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":14},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the aim of the study?","Question",{"text":112,"@type":113},"To evaluate and compare salivary zinc levels in rheumatoid arthritis patients and healthy controls.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How many participants were included and how were they grouped?",{"text":117,"@type":113},"A total of 20 participants were included and divided into two equal groups of 10: healthy controls and rheumatoid arthritis patients.",{"name":119,"@type":110,"acceptedAnswer":120},"What were the main salivary zinc level findings?",{"text":121,"@type":113},"Rheumatoid arthritis patients showed a higher average salivary zinc level (83.52 ± 5.9 μg/dL) compared with controls (69.56 ± 11.2 μg/dL).","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},460306,1790758186,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":14,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":81,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":129,"read_time":39,"preview_page_count":4},3985747859154,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Original Research  \nSalivary Zinc Levels in Rheumatoid Arthritis  \nAnshul Sharma1, Anjali Arya2, Chetan Kumar Sharma3, Ankit Gupta4, Richa Sharma5, Madhvika Shah6  \n1Department of Physiology, Sudha Medical College and Hospital, Jagpura, Kota, Rajasthan, India, 2Department of Microbiology, Virendra Kumar Sakhlecha Government Medical College, Neemuch, MP, India, 3Department of Community Medicine, Virendra Kumar Sakhlecha Government Medical College, Neemuch, MP, India, 4Department of Pathology, Virendra Kumar Sakhlecha Government Medical College, Neemuch, MP, India, 5Department of Pathology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India, 6Department of Physiology, RUHS College of Medical Sciences, Jaipur, Rajasthan, India  \nSubmitted: 15‑Jul‑2025  \nRevised: 27‑Jul‑2025  \nAccepted: 10‑Aug‑2025  \nPublished: 17‑Dec‑2025  \nAbstract  \nBackground: This study aimed to evaluate and compare salivary zinc levels in individuals diagnosed with rheumatoid arthritis and healthy controls. Materials and Methods: A total of 20 participants were included in the study after obtaining informed consent. The participants were divided into two equal groups. Group 1 consisted of 10 healthy individuals who served as controls, while Group 2 included 10 individuals diagnosed with rheumatoid arthritis. Saliva samples were collected from all participants, and the zinc levels were measured and analyzed to determine any differences between the two groups. Results: The average salivary zinc level in the rheumatoid arthritis group (Group 2) was 83.52 ± 5.9 μg/dL. In comparison, the control group (Group 1) showed a lower mean level of 69.56 ± 11.2 μg/dL. This indicates a noticeable difference in zinc concentrations between the two groups. Conclusion: Based on the findings, individuals with rheumatoid arthritis exhibited higher salivary zinc levels compared to healthy controls. This suggests that salivary zinc concentration may be altered in patients with rheumatoid arthritis and could potentially serve as a marker for disease activity or metabolic changes associated with the condition.  \nKeywords: Rheumatoid arthritis, saliva, zinc   \nIntroduction  \nRheinuflmamatoidmatorayrthjroitiinst  \n(RA) is the most common disease worldwide. It is a  \nchronic, complex, and heterogeneous autoimmune disorder characterized by ongoing inflammation of synovial (diarthrodial) joints. This inflammation often leads to symmetric polyarthritis and thickening of the synovial membrane, eventually causing progressive joint damage, cartilage and bone destruction, and visible deformities.[1,2]  \nRA is not limited to joint involvement; it also affects multiple systems throughout the body, resulting in extra‑articular manifestations. Comorbid conditions are frequently observed, contributing to significant physical disability, reduced quality of life, and a  \n\n| Access this article online |  |\n| --- | --- |\n| Quick Response Code:\u003Cbr>| Website: [https://journals.lww.com/jpbs](https://journals.lww.com/jpbs) |\n|  | DOI: 10.4103/jpbs.jpbs_1241_25 |\n\nmortality rate that is nearly twice as high as that of the general population. Predicting the onset of RA remains a challenge in personalized medicine and depends on understanding gene–environment interactions, cytokine profiles, and the presence of specific autoantibodies. [3–5]  \nZinc is a vital trace element involved in the functioning of approximately 300 enzymes and hormones in the human body.[6,7] These enzymes play critical roles in the metabolism of proteins, carbohydrates, fats, and nucleic acids. Zinc is also an essential structural component  \n\n| Address for correspondence: Dr. Ankit Gupta,\u003Cbr>Department of Pathology, Virendra Kumar Sakhlecha Government Medical College, Neemuch, MP, India.\u003Cbr>E-mail: [ankitchd1988@gmail.com](ankitchd1988@gmail.com) |\n| --- |\n| This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License (CC BY-NC-ND), where it ","cbCaitXuGDUaLxLo","https://ap.wps.com/l/cbCaitXuGDUaLxLo","pdf",527429,"English","# Abstract\n# Introduction\n# Material and Methods\n# Results\n# Discussion\n# Conclusion","[{\"question\":\"What was the aim of the study?\",\"answer\":\"To evaluate and compare salivary zinc levels in rheumatoid arthritis patients and healthy controls.\"},{\"question\":\"How many participants were included and how were they grouped?\",\"answer\":\"A total of 20 participants were included and divided into two equal groups of 10: healthy controls and rheumatoid arthritis patients.\"},{\"question\":\"What were the main salivary zinc level findings?\",\"answer\":\"Rheumatoid arthritis patients showed a higher average salivary zinc level (83.52 ± 5.9 μg/dL) compared with controls (69.56 ± 11.2 μg/dL).\"}]","Salivary Zinc Levels in Rheumatoid Arthritis | PDF"]