[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-148389-en":3,"doc-seo-148389-105":30,"detail-sidebar-cat-0-en-105":91},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":4,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":27,"seo_description":14,"update_tm":28,"read_time":29},148389,1374402739827,"Nguyễn Văn Học","https://ap-avatar.wpscdn.com/avatar/14000c97e7351f1a627?x-image-process=image/resize,m_fixed,w_180,h_180&k=1787885694763230660",7,"Healthcare","Safety Assessment of Monosaccharides and Disaccharidesas Used in Cosmetics - Public Comment Scientific Literature Review","Safety assessment summarizes the scientific evidence on monosaccharides and disaccharides used as cosmetic ingredients, framed as a public comment scientific literature review. The document invites interested parties to submit additional published data or make available unpublished data for consideration. It specifies a 60-day comment period after the August 12, 2013 release date and states that submitted unpublished information will be reviewed in open CIR meetings and made available for citation in peer-reviewed scientific literature. It also identifies the expert panel and preparation team.","Safety Assessment of Monosaccharides and Disaccharidesas Used in Cosmetics  \nStatus: Scientific Literature Review for Public Comment  \nRelease Date: August 12 , 2013  \nPanel Meeting Date: December 9-10 , 2013  \nAll interested persons are provided 60 days from the above release date to comment on this safety assessment and to identify additional published data that should be included or provide unpublished data which can be made public and included. Information may be submitted without identifying the source or the trade name of the cosmetic product containing the ingredient. All unpublished data submitted to CIR will be discussed in open meetings, will be available at the CIR office for review by any interested party and may be cited in a peer-reviewed scientific journal. Please submit data, comments, or requests to the CIR Director, Dr. Lillian Gill.  \nThe 2013 Cosmetic Ingredient Review Expert Panel members are: Chairman, Wilma F. Bergfeld, M.D., F.A.C.P.; Donald V. Belsito, M.D. ; Ronald A. Hill, Ph.D. ; Curtis D. Klaassen, Ph.D. ; Daniel C. Liebler, Ph.D. ; James G. Marks, Jr., M.D., Ronald C. Shank, Ph.D.; Thomas J. Slaga, Ph.D.; and Paul W. Snyder, D.V.M., Ph.D. The CIR Director is Lillian J. Gill, D.P.A. This safety assessment was prepared by Monice M. Fiume, Senior Scientific Analyst/Writer and Bart Heldreth, Ph.D., Chemist.  \n© Cosmetic Ingredient Review  \n1101 17th Street, NW, Suite 412 ♢ Washington, DC 20036-4702 ♢ ph 202.331.0651 ♢ fax 202.331.0088 ♢  \n[cirinfo@cir-safety.org](cirinfo@cir-safety.org)  \nTABLE OF CONTENTS  \nIntroduction................................................................................................................................................................................................................................. 1  \nChemistry.................................................................................................................................................................................................................................... 1  \nDefinition............................................................................................................................................................................................................................... 1  \nChemical and Physical Properties ..........................................................................................................................................................................................2  \nNatural Occurrence and Methods of Manufacture .................................................................................................................................................................2  \nConstituents/Impurities ..........................................................................................................................................................................................................2  \nUse ..............................................................................................................................................................................................................................................2  \nCosmetic ................................................................................................................................................................................................................................2  \nNon-Cosmetic........................................................................................................................................................................................................................2  \nToxicokinetics .............................................................................................................................................................................................................................3  \nDermal Permeation .................................................................................","cbCaigTZLZBXAdQv","https://ap.wps.com/l/cbCaigTZLZBXAdQv","pdf",928174,1,28,"English","en",105,"# Introduction\n# Chemistry\n## Definition\n## Chemical and Physical Properties\n## Natural Occurrence and Methods of Manufacture\n## Constituents/Impurities\n# Use\n## Cosmetic\n## Non-Cosmetic\n# Toxicokinetics\n## Dermal Permeation\n## In Vitro\n## In Vivo\n# Toxicological Studies\n## Single Dose (Acute) Toxicity\n## Dermal\n## Repeated Dose Toxicity\n## Ocular Irritation\n## In Vitro\n## In Vivo","[{\"question\":\"What is the purpose of this document on monosaccharides and disaccharides in cosmetics?\",\"answer\":\"It presents a scientific literature review safety assessment for monosaccharides and disaccharides used in cosmetic products and invites public input to strengthen the evidence base.\"},{\"question\":\"How long is the public comment period and what can people submit?\",\"answer\":\"Comments can be submitted within 60 days from the August 12, 2013 release date, including additional published data or unpublished data that can be made public.\"},{\"question\":\"Who prepared the safety assessment and who serves as the expert panel leadership?\",\"answer\":\"The CIR Director is Lillian J. Gill, and the assessment was prepared by Monice M. Fiume and Bart Heldreth, with a panel of expert members listed in the document.\"}]","Safety Assessment of Monosaccharides and Disaccharidesas Used in Cosmetics - Public Comment Scientific Literature Review | PDF",1787779496,71,{"code":4,"msg":31,"data":32},"ok",{"site_id":24,"language":23,"slug":33,"title":13,"keywords":34,"description":14,"schema_data":35,"social_meta":86,"head_meta":88,"extra_data":90,"updated_unix":28},"safety-assessment-of-monosaccharides-and-disaccharidesas-used-in-cosmetics-public-comment-scientific-literature-review","",{"@graph":36,"@context":85},[37,54,68],{"@type":38,"itemListElement":39},"BreadcrumbList",[40,44,48,51],{"item":41,"name":42,"@type":43,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":45,"name":46,"@type":43,"position":47},"https://docshare.wps.com/document/","Document",2,{"item":49,"name":12,"@type":43,"position":50},"https://docshare.wps.com/document/healthcare/",3,{"item":52,"name":13,"@type":43,"position":53},"https://docshare.wps.com/document/safety-assessment-of-monosaccharides-and-disaccharidesas-used-in-cosmetics-public-comment-scientific-literature-review/148389/",4,{"url":52,"name":13,"@type":55,"author":56,"headline":13,"publisher":58,"fileFormat":61,"inLanguage":23,"description":14,"dateModified":62,"datePublished":62,"encodingFormat":61,"isAccessibleForFree":63,"interactionStatistic":64},"DigitalDocument",{"name":9,"@type":57},"Person",{"url":41,"name":59,"@type":60},"DocShare","Organization","application/pdf","2026-08-26",true,{"@type":65,"interactionType":66,"userInteractionCount":4},"InteractionCounter",{"@type":67},"ViewAction",{"@type":69,"mainEntity":70},"FAQPage",[71,77,81],{"name":72,"@type":73,"acceptedAnswer":74},"What is the purpose of this document on monosaccharides and disaccharides in cosmetics?","Question",{"text":75,"@type":76},"It presents a scientific literature review safety assessment for monosaccharides and disaccharides used in cosmetic products and invites public input to strengthen the evidence base.","Answer",{"name":78,"@type":73,"acceptedAnswer":79},"How long is the public comment period and what can people submit?",{"text":80,"@type":76},"Comments can be submitted within 60 days from the August 12, 2013 release date, including additional published data or unpublished data that can be made public.",{"name":82,"@type":73,"acceptedAnswer":83},"Who prepared the safety assessment and who serves as the expert panel leadership?",{"text":84,"@type":76},"The CIR Director is Lillian J. 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