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This systematic review and meta-analysis evaluates safety and efficacy using pooled outcome estimates, with occlusion assessed by Raymond–Roy Occlusion Classification (RROC) and complications analyzed across procedural and clinical events. Results synthesize 12 studies totaling 567 patients.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/safety-and-efficacy-of-the-lvis-evo-device-for-stent-assisted-coiling-of-intracranial-aneurysms-a-systematic-review-and-meta-analysis/462597/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/safety-and-efficacy-of-the-lvis-evo-device-for-stent-assisted-coiling-of-intracranial-aneurysms-a-systematic-review-and-meta-analysis/462597.png","ImageObject",300,407,{"name":42,"@type":43},"Terk","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-11-01","2026-09-30",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",9,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What is the LVIS EVO stent used for in this study?","Question",{"text":63,"@type":64},"It is evaluated as a low-profile stent for stent-assisted coiling (SAC) of intracranial aneurysms, with attention to safety and efficacy outcomes.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"How were aneurysm occlusion and complications assessed?",{"text":68,"@type":64},"Aneurysm occlusion was classified using the Raymond–Roy Occlusion Classification (RROC). Procedural and clinical complication rates were pooled, with statistical confidence intervals reported.",{"name":70,"@type":61,"acceptedAnswer":71},"What overall conclusions does the review reach about LVIS EVO?",{"text":72,"@type":64},"The review reports high technical success, effective aneurysm occlusion, and low complication rates, while recommending prospective studies to confirm long-term outcomes.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},462597,1791155694,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,110,115,119,122,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":107,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":108,"slug":109},7,40,"healthcare",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":112,"show_sort_weight":113,"slug":114},8,"Research & Report",30,"research-report",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":97,"slug":129},19,"General","general",{"code":4,"msg":82,"data":131},{"doc_id":79,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":107,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":139,"language":140,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":12,"update_tm":144,"read_time":108,"preview_page_count":4},1099525198933,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Systematic Review  \nSafety and Efficacy of the LVIS EVO Device for Stent-Assisted Coiling of Intracranial Aneurysms: A Systematic Review and Meta-Analysis  \nAbdulrahim Saleh Alrasheed 1, *, Amna Mutasim Elazrag 2, Rola Hamad Alseghair 3, Majd Nouh Alasmari 4, Mohammad Salem Alqahtani 5 and Hosam Al-Jehani 6,7,8, *  \nAcademic Editor: Mario Ganau  \nReceived: 25 November 2025  \nRevised: 16 December 2025  \nAccepted: 26 December 2025  \nPublished: 29 December 2025  \nCopyright: © 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.  \n1 Department of Neurosurgery, College of Medicine, King Faisal University, Al Ahsa 31982, Saudi Arabia  \n2 Faculty of Medicine, University of Khartoum, Khartoum 11115, Sudan  \n3 College of Medicine, Qassim University, Qassim 51452, Saudi Arabia  \n4 College of Medicine, King Khalid University, Abha 61421, Saudi Arabia  \n5 Neurosurgery Department, King Fahad Hospital of the University, Imam Abdulrahman Bin Faisal University, Khobar 31451, Saudi Arabia  \n6 Department of Neurosurgery, Interventional Neuroradiology and Critical Care Medicine, Imam Abdulrahman Bin Faisal University, Khobar 31451, Saudi Arabia  \n7 Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University Health Centre, Montreal, QC H4A 0B1, Canada  \n8 Department of Neurosurgery, Weill Cornell University, Houston Methodist, Houston, TX 77030, USA  \n* Correspondence: [221414880@student.kfu.edu.sa or abdulrhim2003@hotmail.com](221414880@student.kfu.edu.sa or abdulrhim2003@hotmail.com) (A.S.A.); [hjehani@iau.edu.sa](hjehani@iau.edu.sa) (H.A.-J.)  \nAbstract  \nBackground: The low-profile visualized intraluminal support EVO (LVIS EVO) stent is a novel device for stent-assisted coiling (SAC) that offers improved visibility, radial force, and navigability in tortuous cerebral vessels. This systematic review and metaanalysis evaluated the safety and efficacy of the LVIS EVO stent in treating intracranial aneurysms (IAs) . Methods: A systematic search of PubMed, Web of Science, Cochrane Library, and Scopus databases to identify studies reporting clinical outcomes of LVIS EVO in SAC of IAs was performed. Primary outcomes included aneurysm occlusion based on the Raymond–Roy Occlusion Classification (RROC), procedural, and clinical complication rates. Pooled estimates with 95% confidence intervals (CIs) were calculated using either a fixed-or random-effects model. Heterogeneity was assessed using the I2 statistic. Sensitivity analyses were conducted using the leave-one-out method. Results: Twelve studies involving 567 patients and 586 aneurysms were included. Immediate angiographic results showed complete occlusion (RROC I) in 78%(95% CI: 0.53–0.92), residual neck (RROC II) in 13%(95% CI: 0.08–0.21), and residual aneurysm (RROC III) in 9%(95% CI: 0.02–0.34) . At follow-up, complete obliteration was observed in 73%(95% CI: 0.60–0.83) . Procedural complications occurred in 5%(95% CI: 0.03–0.09), and clinical complications in 6%(95% CI: 0.04–0.10) . Conclusions: The LVIS EVO stent demonstrated high technical success, effective aneurysm occlusion, and low complication rates, supporting its safety and efficacy. Prospective studies are warranted to confirm long-term outcomes.  \nKeywords: intracranial aneurysms; stent-assisted coiling; endovascular treatment; neurointervention  \n1. Introduction  \nIntracranial aneurysms (IAs) are localized dilatations of cerebral arteries that arise due to structural weaknesses in the arterial wall, often at branching points of major vessels within the circle of Willis. Almost 2–3.2% of the global population have IAs. They may remain clinically silent or present with nonspecific symptoms such as persistent headaches, visual disturbances, nausea, vomiting, or cranial nerve palsies. However, their most catastrophic presentation is rupture, leading to subarachnoid h","cbCaiq8Eh44SJqme","https://ap.wps.com/l/cbCaiq8Eh44SJqme","pdf",1062830,16,"English","# Abstract\n# 1. Introduction","[{\"question\":\"What is the LVIS EVO stent used for in this study?\",\"answer\":\"It is evaluated as a low-profile stent for stent-assisted coiling (SAC) of intracranial aneurysms, with attention to safety and efficacy outcomes.\"},{\"question\":\"How were aneurysm occlusion and complications assessed?\",\"answer\":\"Aneurysm occlusion was classified using the Raymond–Roy Occlusion Classification (RROC). Procedural and clinical complication rates were pooled, with statistical confidence intervals reported.\"},{\"question\":\"What overall conclusions does the review reach about LVIS EVO?\",\"answer\":\"The review reports high technical success, effective aneurysm occlusion, and low complication rates, while recommending prospective studies to confirm long-term outcomes.\"}]","Safety and Efficacy of the LVIS EVO Device for Stent-Assisted Coiling of Intracranial Aneurysms - A Systematic Review and Meta-Analysis | PDF",1790764646]