[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-450146-105":59,"doc-detail-450146-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","risk-factors-for-blood-transfusion-during-cesarean-section-in-women-with-major-placenta-previa","Risk factors for blood transfusion during cesarean section in women with major placenta previa","","Risk factors for perioperative blood transfusion during cesarean delivery were investigated in women with major placenta previa. A retrospective single-center cohort study analyzed 110 patients treated at the Department of Obstetrics and Gynecology, Karlsruhe Municipal Hospital, from 2014 to 2021, comparing women who did and did not receive operative blood transfusion. Twenty women (18.2%) required transfusion. No significant differences emerged for maternal age, gestational age, urgency of surgery, or several clinical factors, while previous cesarean section increased odds of perioperative transfusion (OR 4.63, 95% CI 1.65–12.95; Holm-adjusted p = 0.049).",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/risk-factors-for-blood-transfusion-during-cesarean-section-in-women-with-major-placenta-previa/450146/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/risk-factors-for-blood-transfusion-during-cesarean-section-in-women-with-major-placenta-previa/450146.png","ImageObject",300,407,{"name":92,"@type":93},"Aria","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the main objective of the study?","Question",{"text":112,"@type":113},"To identify risk factors for blood transfusion during cesarean section in women with major placenta previa.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How many women with major placenta previa were included, and how many required transfusion?",{"text":117,"@type":113},"A total of 110 women were included, and 20 women (18.2%) required a blood transfusion.",{"name":119,"@type":110,"acceptedAnswer":120},"Which factor was associated with higher odds of perioperative transfusion?",{"text":121,"@type":113},"A history of previous cesarean section was associated with higher odds of perioperative transfusion (OR 4.63, 95% CI 1.65–12.95; Holm-adjusted p = 0.049).","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},450146,1790955420,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":34,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},2336464648322,"https://ap-avatar.wpscdn.com/avatar/2200025388227c56fec?_k=1778556882303663488","[www. nature.com/scientificreports](www. nature.com/scientificreports)  \nOPEN  \nRisk factors for blood transfusion during cesarean section in women with major placenta previa  \nEvgeni Baev1,2􀀍, Karin Roth1, Jana Nagel1, Janine Krämer1, Ralf Dittrich2,3, Lothar Häberle2,3 & Andreas Müller1,2  \nTo identify risk factors for blood transfusion during cesarean section in women with major placenta previa. We conducted a retrospective single-center cohort study of 110 women with major placenta previa who underwent cesarean section atthe Department of Obstetrics and Gynecology, Karlsruhe Municipal Hospital, between 2014 and 2021. We grouped patients by whether they received aperioperative blood transfusion. Maternal characteristics and clinical factors were compared to identify risk factors. Twenty women (18.2%) required a blood transfusion. No significant differences were observed between groups for maternal age, gestational age at delivery, elective versus urgent cesarean section, antepartum bleeding, use of assisted reproductive technology, or history of curettage. Prior cesarean section was associated with higher odds of perioperative transfusion (OR  \n4.63, 95% CI 1.65–12.95; Holm-adjusted p = 0.049) . Major placenta previa itself is a recognized risk factor for obstetric hemorrhage and transfusion. Our study shows that a history of previous cesarean section is associated with an additional increase in transfusion risk. These findings emphasize the importance of careful preoperative planning and counseling in this high-risk population.  \nKeywords Placenta previa, Cesarean section, Blood transfusion  \nMajor placenta previa is one of the most challenging obstetric conditions and can have devastating consequences for both mother and fetus. It can result in catastrophic hemorrhage that may require cesarean hysterectomy and massive blood transfusion. The prevalence of placenta previa is estimated at 0.4–0.5%, with substantial regional variation worldwide1,2. Its frequency has increased in recent decades, largely paralleling the global rise in cesarean deliveries. In a prospective study spanning 19 years, Kollmann et al. reported a 50% increase in the incidence of placenta previa3.  \nPlacenta previa is defined as the presence of placental tissue covering or reaching the internal cervical os beyond 20 weeks of gestation4. Nearly 90% of low-lying placentas diagnosed in the second trimester resolve before term through the phenomenon of placental “migration” or trophotropism5. Persistent placenta previa at term, however, is strongly associated with severe maternal morbidity.  \nPrevious studies have identified several risk factors for major placenta previa, including advanced maternal age, multiparity, assisted reproductive techniques, previous curettage, and particularly a history of cesarean delivery6–9. The rising global cesarean rate has therefore been recognized as a major contributor to the increasing incidence of placenta previa10.  \nMajor placenta previa is also strongly associated with life-threatening maternal hemorrhage and the need for blood transfusion. Several studies have attempted to identify risk factors for transfusion among women with placenta previa11–14. However, many of these studies combined major and minor placenta previa, despite evidence that the risk profile differs significantly between these groups15, 16.  \nTo address this gap, our study focused exclusively on women with major placenta previa, defined according to the updated AIUM classification17. We aimed to identify clinical risk factors for perioperative blood transfusion in this high-risk population.  \n1Department of Obstetrics and Gynecology, Karlsruhe Municipal Hospital, Moltkestrasse 90, 76133 Karlsruhe, Germany. 2Friedrich Alexander University of Erlangen–Nuremberg, Erlangen, Germany. 3Department of Obstetricsand Gynecology, Erlangen University Hospital, Erlangen, Germany. 􀀍 email: [evgeni.baev@klinikum-karlsruhe.de](evgeni.baev@klinikum-karlsruhe.de)  \n","cbCaio3CoXyw1WOy","https://ap.wps.com/l/cbCaio3CoXyw1WOy","pdf",1196226,"English","# Methods\n## Patient selection\n## Variables","[{\"question\":\"What is the main objective of the study?\",\"answer\":\"To identify risk factors for blood transfusion during cesarean section in women with major placenta previa.\"},{\"question\":\"How many women with major placenta previa were included, and how many required transfusion?\",\"answer\":\"A total of 110 women were included, and 20 women (18.2%) required a blood transfusion.\"},{\"question\":\"Which factor was associated with higher odds of perioperative transfusion?\",\"answer\":\"A history of previous cesarean section was associated with higher odds of perioperative transfusion (OR 4.63, 95% CI 1.65–12.95; Holm-adjusted p = 0.049).\"}]","Risk factors for blood transfusion during cesarean section in women with major placenta previa | PDF",1790732249,18]