[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-609339-105":3,"detail-sidebar-cat-0-en-105":80,"doc-detail-609339-en":130},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":73,"head_meta":75,"extra_data":77,"updated_unix":79},105,"en","remnant-cholesterol-as-a-predictor-of-no-reflow-phenomenon-in-patients-with-st-segment-elevation-myocardial-infarction","Remnant Cholesterol as a Predictor of No-Reflow Phenomenon in Patients With ST-Segment Elevation Myocardial Infarction","","Remnant cholesterol (RC) is examined as a potential biomarker for predicting the no-reflow phenomenon in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention. Patients were divided into a no-reflow group (n=90) and a non-no-reflow group (n=350). RC was computed as total cholesterol minus LDL-C and HDL-C. RC independently predicted no-reflow (OR=1.28, P\u003C.001) alongside diabetes, stent length, door-to-balloon time, symptom-to-admission time, and thrombus presence, with strong discrimination (AUC=0.923, P\u003C.001).",{"@graph":14,"@context":72},[15,34,55],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/research-report/","Research & Report",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/remnant-cholesterol-as-a-predictor-of-no-reflow-phenomenon-in-patients-with-st-segment-elevation-myocardial-infarction/609339/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/remnant-cholesterol-as-a-predictor-of-no-reflow-phenomenon-in-patients-with-st-segment-elevation-myocardial-infarction/609339.png","ImageObject",300,407,{"name":42,"@type":43},"Fans","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-28","2026-10-18",true,{"@type":52,"interactionType":53,"userInteractionCount":30},"InteractionCounter",{"@type":54},"ViewAction",{"@type":56,"mainEntity":57},"FAQPage",[58,64,68],{"name":59,"@type":60,"acceptedAnswer":61},"How was remnant cholesterol (RC) calculated in the study?","Question",{"text":62,"@type":63},"RC was calculated as total cholesterol minus low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C).","Answer",{"name":65,"@type":60,"acceptedAnswer":66},"Which factors were independent predictors of no-reflow?",{"text":67,"@type":63},"RC was an independent predictor (OR=1.28, P\u003C.001). Other independent predictors included diabetes mellitus, stent length, door-to-balloon time, symptom-to-admission time, and presence of thrombus.",{"name":69,"@type":60,"acceptedAnswer":70},"How well did RC predict no-reflow after primary PCI?",{"text":71,"@type":63},"RC showed strong predictive performance with an area under the curve (AUC) of 0.923 (P\u003C.001) for no-reflow development.","https://schema.org",{"og:url":32,"og:type":74,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":76,"canonical":32},"index,follow",{"doc_id":78,"site_id":7},609339,1792789471,{"code":4,"msg":81,"data":82},"success",[83,87,91,95,100,105,110,114,119,122,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":84,"show_sort_weight":85,"slug":86},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":88,"show_sort_weight":89,"slug":90},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":92,"show_sort_weight":93,"slug":94},"Exam",70,"exam",{"id":96,"doc_module":4,"doc_module_name":25,"category_name":97,"show_sort_weight":98,"slug":99},5,"Comic",60,"comic",{"id":101,"doc_module":4,"doc_module_name":25,"category_name":102,"show_sort_weight":103,"slug":104},6,"Technology",50,"technology",{"id":106,"doc_module":4,"doc_module_name":25,"category_name":107,"show_sort_weight":108,"slug":109},7,"Healthcare",40,"healthcare",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":112,"slug":113},8,30,"research-report",{"id":115,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},9,"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":96,"slug":129},19,"General","general",{"code":4,"msg":81,"data":131},{"doc_id":78,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":111,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":30,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":106,"language":139,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":12,"update_tm":143,"read_time":144},5909892330395,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","Original Manuscript  \nRemnant Cholesterol as a Predictor of No-Reflow Phenomenon in Patients With ST-Segment Elevation Myocardial Infarction  \nAngiology 2026, Vol. 77(9) 1191–1197 © The Author(s) 2025  \nArticle reuse guidelines: [sagepub.com/journals-permissions](sagepub.com/journals-permissions)[ ](sagepub.com/journals-permissions)[DOI: 10.1177/00033197251395822](DOI: 10.1177/00033197251395822)  \n[journals.sagepub.com/home/ang](journals.sagepub.com/home/ang)  \nOmer Dogan, MD 1, Hasan Ali Barman, MD 1, Abdullah Omer Ebeoglu, MD 1, Sevval Ilke Guneysu, MD 1, Ali Nayir, MD 1, Melike Kaya, MD 1, Adem Atıcı, MD2, Khayal Mirzayev, MD3, Okay Abaci, MD4, Murat Kazim Ersanli, MD 1, Sait Mesut Dogan, MD 1,and Veysel Oktay, MD 1  \nAbstract  \nRemnant cholesterol (RC) has been implicated in the progression of atherosclerotic cardiovascular disease. However, the impact of RC levels on the occurrence of no-reflow in patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (pPCI) remains poorly understood. Patients were classified into 2 groups: those (n = 90) who developed no-reflow ( +) and those (n = 350) who did not develop no-reflow (−). RC was calculated as total cholesterol minus low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). RC (Odds Ratio [OR] = 1.28, P \u003C .001), diabetes mellitus (OR = 2.72, P = .002), stent length (OR = 1.07, P = .020), door-to-balloon time (OR = 1.04, P = .047), symptom-to-admission time (OR = 2.07, P = .002) and presence of thrombus (OR = 2.34, P \u003C 0.001) were independent predictors of no-reflow. RC was shown to predict no-reflow development (Area under the curve [AUC] = 0.923, P \u003C .001). The present study revealed a significant association between RC levels and the occurrence of the no-reflow phenomenon following pPCI in patients with STEMI. Assessment of RC levels may assist in identifying high-risk groups in STEMI patients and may prove to be an important factor to manage for cardiovascular health.  \nKeywords  \nremnant cholesterol, no-reflow, STEMI, primary PCI  \nIntroduction  \nAlthough the field of medicine has witnessed revolutionary advancements including the introduction of innovative treatment strategies, ST-segment elevation myocardial infarction (STEMI) continues to be a major contributor to morbidity and mortality worldwide 1 STEMI is mainly treated by primary percutaneous coronary intervention (pPCI) .1 An important complication associated with STEMI is post-revascularization coronary no-reflow (NR) .2 In this condition, insufficient myocardial perfusion is experienced even though the occluded segment had been mechanically reopened with PCI. This complication has proven to be a main cause of morbidity and mortality in STEMI patients irrespective of the size of the infarct.3 The rate of incidence of NR in large registries is 5% to 20% .2-4  \nThe cholesterol content of triglyceride-rich lipoprotein (TRL) is known as remnant cholesterol (RC) . Intermediatedensity lipoprotein (IDL), very-low-density lipoprotein (VLDL) and chylomicron remnant constitute the RC.5 RC has recently been considered as a factor that can increase the risk  \nofatherosclerotic cardiovascular diseases.5-7 Several different vascular disorders like atherogenesis, inflammation and endothelial dysfunction can be caused by a buildup of RC in the subendothelial area.8 Also genetically increased RC levels are associated with coronary artery disease (CAD) .5-9 Nevertheless, the prognostic importance of increased RC levels in STEMI patients still needs to be investigated in detail.9 The effect of RC levels on NR in STEMI patients has not been investigated.  \n1 Department of Cardiology, Istanbul University-Cerrahpaşa, Institute of Cardiology, Turkey  \n2Goztepe Training and Research Hospital, Department of Cardiology, Istanbul Medeniyet University, Faculty of Medicine, Turkey  \n3Department of Cardiology, Koc University Hospital, Ista","cbCaiifcc3RfImDG","https://ap.wps.com/l/cbCaiifcc3RfImDG","pdf",502443,"English","# Introduction\n# Methods\n## Study Population and Data Collection\n## Definitions and Outcomes\n# Results\n# Discussion\n# Conclusions","[{\"question\":\"How was remnant cholesterol (RC) calculated in the study?\",\"answer\":\"RC was calculated as total cholesterol minus low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C).\"},{\"question\":\"Which factors were independent predictors of no-reflow?\",\"answer\":\"RC was an independent predictor (OR=1.28, P\\u003c.001). Other independent predictors included diabetes mellitus, stent length, door-to-balloon time, symptom-to-admission time, and presence of thrombus.\"},{\"question\":\"How well did RC predict no-reflow after primary PCI?\",\"answer\":\"RC showed strong predictive performance with an area under the curve (AUC) of 0.923 (P\\u003c.001) for no-reflow development.\"}]","Remnant Cholesterol as a Predictor of No-Reflow Phenomenon in Patients With ST-Segment Elevation Myocardial Infarction | PDF",1792358676,18]