[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-415858-105":59,"doc-detail-415858-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","recurrent-cystitis-glandularis-of-the-bladder-case-report-and-review","Recurrent cystitis glandularis of the bladder - case report and review","","Recurrent cystitis glandularis is a rare benign bladder lesion that may mimic malignancy, particularly the intestinal subtype with debated premalignant potential. A 36-year-old man presented with irritative urinary symptoms and microscopic hematuria; cystoscopy showed multiple nodular non-urothelial lesions. Transurethral resection confirmed cystitis glandularis and cystitis cystica with intestinal metaplasia, without atypia or invasion. Despite postoperative symptom improvement, recurrence occurred one year later, underscoring the need for accurate histopathology and regular cystoscopic surveillance to exclude malignant transformation.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/recurrent-cystitis-glandularis-of-the-bladder-case-report-and-review/415858/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/recurrent-cystitis-glandularis-of-the-bladder-case-report-and-review/415858.png","ImageObject",300,407,{"name":92,"@type":93},"Putri","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is cystitis glandularis and why can it resemble cancer?","Question",{"text":113,"@type":114},"Cystitis glandularis is a rare benign bladder lesion with glandular metaplasia. Its intestinal subtype can simulate bladder carcinoma, making histological confirmation necessary.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What findings confirmed the diagnosis in the reported case?",{"text":118,"@type":114},"Transurethral resection showed cystitis glandularis associated with cystitis cystica, with intestinal-type metaplasia. No cytological atypia or stromal invasion was observed.",{"name":120,"@type":111,"acceptedAnswer":121},"How did recurrence occur and what follow-up was proposed?",{"text":122,"@type":114},"After initial postoperative improvement, the patient developed recurrent irritative urinary symptoms one year later. A cystoscopic surveillance schedule every 6 months was proposed due to lack of consensus on follow-up.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},415858,1790716741,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":19,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":52,"preview_page_count":4},962085571259,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","Urology Case Reports 64 (2026) 103310  \nContents lists available at ScienceDirect  \nUrology Case Reports  \njournal [homepage:](homepage: www.elsevier.com/locate/eucr)[ www.elsevier.com/locate/eucr](homepage: www.elsevier.com/locate/eucr)  \n| Oncology\u003Cbr>Recurrent cystitis glandularis of the bladder: case report and review\u003Cbr>*\u003Cbr>Abdelhakim Oukouhou , Mohamed Amine Harchaoui , Yassine Ameur , Mohamed Tetou , Mohammed Mrabti , Younes Boukhlifi , Abdessamad El Bahri , Mohamed Alami , Ahmed Ameur\u003Cbr>Military Hospital Mohamed V ofRabat, 10100, Morocco |  |  | |\n| --- | --- | --- | --- |\n| A R T I C L E I N F O |  | A B S T R A C T |  |\n| Keywords:\u003Cbr>Cystitis glandularis\u003Cbr>Cystitis cystica Bladder Adenocarcinoma |  | Cystitis glandularis is a rare benign lesion of the bladder that can mimic malignancy. The intestinal subtype is notable for its recurrence and debated premalignant potential.\u003Cbr>we present the case of a 36-year-old male presented with irritative urinary symptoms and microscopic hematuria. Cystoscopy showed multiple nodular, non-urothelial lesions. Transurethral resection confirmed cystitis glandularis and cystitis cystica with intestinal metaplasia, without atypia or invasion. The patient improved postoperatively but developed recurrence one year later.\u003Cbr>Intestinal-type cystitis glandularis is a benign yet recurrent lesion that may simulate bladder carcinoma. Accurate histopathological diagnosis and regular cystoscopic follow-up are essential to exclude malignant transformation. |  |\n\n1. Introduction  \nGlandular cystitis is a rare, benign lesion of the urinary bladder characterized by glandular metaplasia of the urothelium. It arises from the transformation of benign urothelial invaginations, known as von Brunn’s nests, into glandular, mucus-secreting structures, sometimes associated with cystic dilatations.1,2  \nAlthough traditionally considered a reactive condition secondary to chronic mucosal irritation,1,3 its pathogenesis remains a matter of debate.  \nClinically, glandular cystitis is most often asymptomatic and discovered incidentally during cystoscopy or histopathological examination. When symptomatic, it may present with irritative voiding symptoms or hematuria.4,5 Endoscopically, it may mimic a bladder tumor, making histological confirmation essential to rule out malignancy, particularly adenocarcinoma.6 Immunohistochemistry can be a useful adjunct in difficult cases.7  \nThe overall prognosis is favorable, but the intestinal variant has been discussed as a potential premalignant lesion,2,6 raising the need for surveillance in selected patients.  \nWe report the case of a patient with glandular cystitis and provide areview of the current literature to highlight its clinical, histological, and prognostic features.  \n2. Case presentation  \nA 36-year-old male, single, with no significant past medical history and no history of chronic smoking, presented with lower urinary tract symptoms consisting of pollakiuria and burning micturition.  \nUrinalysis and urine culture revealed microscopic hematuria without evidence of urinary tract infection.  \nAn uro-CT scan demonstrated a posterior bladder wall thickening with a budding intraluminal mass, measuring 48 × 56 mm, with mild contrast enhancement.  \nCystoscopy revealed multiple nodular lesions diffusely involving the entire posterior wall as well as the trigonal and retrotrigonal regions. These lesions had a non-urothelial appearance, raising suspicion for anon-conventional bladder tumor.  \nThe patient underwent a transurethral resection of the bladder lesions (TURB). Histopathological examination showed cystitis glandularis associated with cystitis cystica, with areas of intestinal-type metaplasia, characterized by mucin-secreting columnar epithelium. Importantly, no cytological atypia or stromal invasion was observed.  \nGiven the absence of consensus on follow-up strategy, a cystoscopic surveillance schedule every 6 months was proposed.  \nFollow-up demonstrated a ","cbCailtRoKUncsk6","https://ap.wps.com/l/cbCailtRoKUncsk6","pdf",1510636,"English","# Introduction\n# Case presentation\n# Discussion","[{\"question\":\"What is cystitis glandularis and why can it resemble cancer?\",\"answer\":\"Cystitis glandularis is a rare benign bladder lesion with glandular metaplasia. Its intestinal subtype can simulate bladder carcinoma, making histological confirmation necessary.\"},{\"question\":\"What findings confirmed the diagnosis in the reported case?\",\"answer\":\"Transurethral resection showed cystitis glandularis associated with cystitis cystica, with intestinal-type metaplasia. No cytological atypia or stromal invasion was observed.\"},{\"question\":\"How did recurrence occur and what follow-up was proposed?\",\"answer\":\"After initial postoperative improvement, the patient developed recurrent irritative urinary symptoms one year later. A cystoscopic surveillance schedule every 6 months was proposed due to lack of consensus on follow-up.\"}]","Recurrent cystitis glandularis of the bladder - case report and review | PDF",1790603191]