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Literature has described synchronous detection of colon cancer with other primary tumors, either within syndromic frameworks such as Lynch syndrome or as sporadic events. This article reports and reviews reported synchrony of colorectal cancer and renal carcinoma, highlighting an exceptionally uncommon presentation.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/rectorrhagia-revealing-synchronous-colonic-adenocarcinoma-and-papillary-renal-cell-carcinoma-type-1-an-exceptional-case-report/383693/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/rectorrhagia-revealing-synchronous-colonic-adenocarcinoma-and-papillary-renal-cell-carcinoma-type-1-an-exceptional-case-report/383693.png","ImageObject",300,407,{"name":92,"@type":93},"Ophelia","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why is synchronous colorectal cancer and renal cell carcinoma considered rare?","Question",{"text":112,"@type":113},"The synchronous occurrence of colorectal cancer and renal cell carcinoma is uncommon, and it is even rarer when the renal cell carcinoma is of papillary origin, with only two cases previously reported in the literature.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What diagnostic findings were used to identify the colorectal cancer and renal cell carcinoma?",{"text":117,"@type":113},"Colonoscopy with biopsy revealed a moderately differentiated adenocarcinoma with an immunohistochemical profile consistent with colorectal origin, while thoracic-abdominal-pelvic CT showed metastatic disease and a left kidney lesion, confirmed by kidney biopsy suggesting papillary type 1 renal cell carcinoma.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the patient managed after diagnosis?",{"text":121,"@type":113},"Due to advanced disease stage, the patient was started on palliative chemotherapy and genetic counseling was sought.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},383693,1790677902,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":81,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":39},7971461741311,"https://ap-avatar.wpscdn.com/avatar/74000253aff267980c6?x-image-process=image/resize,m_fixed,w_180,h_180&k=1779345379180704826","Urology Case Reports 49 (2023) 102434  \nContents lists available at ScienceDirect  \nUrology Case Reports  \njournal [homepage:](homepage: www.elsevier.com/locate/eucr)[ www.elsevier.com/locate/eucr](homepage: www.elsevier.com/locate/eucr)  \n| Oncology\u003Cbr>Rectorrhagia revealing synchronous colonic adenocarcinoma and papillary renal cell carcinoma type 1, an exceptional case report |  | |\n| --- | --- | --- |\n| Yacoub A. Okiyeha, b, *, Ibrahim Boukhannousa, b, Anouar El Moudanea, b, Jdaini Ahmed a, b, Craig Aurtz Tombeta, b, Ali Barkia, b\u003Cbr>a Department of Urology, Mohammed VI University Hospital, Oujda, Morocco\u003Cbr>b Faculty of Medicine and Pharmacy of Oujda, Mohammed First University of Oujda, Morocco |  |  |\n| A R T I C L E I N F O\u003Cbr>Keywords:\u003Cbr>Rectorrhagia Synchronous\u003Cbr>Colonic adenocarcinoma Renal cell carcinoma | A B S T R A C T |  |\n|  | Colorectal cancer (CRC) is the most prevalent type of cancer affecting the gastrointestinal tract. The synchronous occurrence of CRC and renal cell carcinoma is rare, and even rarer when the renal cell carcinoma is of papillary origin, with only two cases reported in the literature. The synchronous detection of colon cancer and other primary tumors has been extensively studied and reported in the literature, either falling within the framework of well-defined clinical syndromes such as Lynch syndrome or occurring sporadically. This article aims to report and expose a literature review of the synchrony of colorectal cancer and renal carcinoma. |  |\n\n1. Introduction  \nThe simultaneous occurrence of primary malignant tumors in the same patient is rare, and in most cases, the risk of a patient being treated for one cancer developing a second is similar to that of the general population.1 However, this possibility raises the question of a possible common carcinogenesis mechanism involving both hereditary, immune, and environmental factors. The synchronous detection of colon cancer and other primary tumors has been documented in various publications, either within the context of well-defined clinical syndromes such as Lynch syndrome or in sporadic cases. The co-occurrence of colon carcinoma and renal cell carcinoma is infrequent, and we report an unusual case of the concurrent presence of papillary type 1 renal cell carcinoma and colorectal cancer.  \n2. Case report  \nA 64-year-old patient with a medical history of type 1 diabetes on insulin and arterial hypertension on dual therapy presented to the emergency room with intermittent rectal bleeding for three months, associated with proctalgia but without abdominal pain or hematuria, in the context of a deteriorating general state with apyrexia. The patient was conscious and stable on hemodynamic and respiratory examination, with a normal digital rectal examination. Laboratory analysis showed the patient’s hemoglobin was 9.8 g/dL, platelet count was 342,000/  \nmm3, and renal function was normal.  \nThe following day, the gastroenterology department performed a colonoscopy with biopsies, revealing a reshaped micro-budding lesion located 35 cm from the anal verge, reducing the light and making it impassable. Histological analysis of the biopsy showed the presence of a moderately differentiated adenocarcinoma with an immunohistochemical profile (CK20+, CDX2+, CK7-) consistent with colorectal origin (Fig. 1). Tumor markers were normal (CA 125; CA 15–3; CA19-9) except for ACE, which was at 80 ng/mL.  \nA thoracic-abdominal-pelvic CT scan revealed circumferential and partially stenosing thickening of the rectosigmoid hinge with infiltration of the surrounding fat, peritoneal carcinomatosis, lung and bone metastasis, and a lesion in the upper two-thirds of the left kidney with infiltration of the peri-lesional fatty space (Fig. 2). A left kidney biopsy was performed, which suggested type 1 papillary renal cell carcinoma (Fig. 3).  \nDue to the advanced stage of the disease, the patient was started on palliative chemotherapy, and genetic counseling was sou","cbCaigrCEaRA9O28","https://ap.wps.com/l/cbCaigrCEaRA9O28","pdf",3368796,"English","# Introduction\n# Case report\n# Discussion","[{\"question\":\"Why is synchronous colorectal cancer and renal cell carcinoma considered rare?\",\"answer\":\"The synchronous occurrence of colorectal cancer and renal cell carcinoma is uncommon, and it is even rarer when the renal cell carcinoma is of papillary origin, with only two cases previously reported in the literature.\"},{\"question\":\"What diagnostic findings were used to identify the colorectal cancer and renal cell carcinoma?\",\"answer\":\"Colonoscopy with biopsy revealed a moderately differentiated adenocarcinoma with an immunohistochemical profile consistent with colorectal origin, while thoracic-abdominal-pelvic CT showed metastatic disease and a left kidney lesion, confirmed by kidney biopsy suggesting papillary type 1 renal cell carcinoma.\"},{\"question\":\"How was the patient managed after diagnosis?\",\"answer\":\"Due to advanced disease stage, the patient was started on palliative chemotherapy and genetic counseling was sought.\"}]","Rectorrhagia revealing synchronous colonic adenocarcinoma and papillary renal cell carcinoma type 1, an exceptional case report | PDF",1790258787]