[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-331169-105":59,"doc-detail-331169-en":122},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":115,"head_meta":117,"extra_data":119,"updated_unix":121},105,"en","reconsidering-routine-histopathological-examination-of-gallbladder-specimens-in-cholecystectomy-optimizing-clinical-practice-and-resource-management","Reconsidering Routine Histopathological Examination of Gallbladder Specimens in Cholecystectomy - Optimizing Clinical Practice and Resource Management","","Cholecystectomy is widely performed, and routine post-operative histopathological examination (HPE) of gallbladder specimens is commonly used to exclude gallbladder cancer (GBC), despite the absence of visible anomalies. This retrospective cohort study in Australia evaluated whether routine HPE is necessary by selectively processing specimens suspected of GBC. From 2023 records, 266 specimens were analyzed, showing no GBC cases and limited premalignant findings, supporting a selective, resource-conscious approach.",{"@graph":69,"@context":114},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/reconsidering-routine-histopathological-examination-of-gallbladder-specimens-in-cholecystectomy-optimizing-clinical-practice-and-resource-management/331169/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/reconsidering-routine-histopathological-examination-of-gallbladder-specimens-in-cholecystectomy-optimizing-clinical-practice-and-resource-management/331169.png","ImageObject",300,407,{"name":92,"@type":93},"Ezra","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-24","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108],{"name":109,"@type":110,"acceptedAnswer":111},"What were the key findings and what approach is recommended?","Question",{"text":112,"@type":113},"Among 266 specimens, no gallbladder cancer cases were found and a small proportion had premalignant features. The study recommends adopting a selective strategy where only specimens with macroscopic abnormalities undergo HPE, especially in regions with low GBC incidence, to reduce workload and costs without compromising outcomes.","Answer","https://schema.org",{"og:url":83,"og:type":116,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":118,"canonical":83},"index,follow",{"doc_id":120,"site_id":62},331169,1790033775,{"code":4,"msg":5,"data":123},{"doc_id":120,"user_id":124,"nickname":92,"user_avatar":125,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":126,"file_id":127,"file_url":128,"file_type":129,"file_size":130,"view_count":34,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":34,"language":131,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":132,"faqs":133,"seo_title":134,"seo_description":67,"update_tm":135,"read_time":136,"preview_page_count":4},1099514068035,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Open Access Original  \nArticle DOI: 10.7759/cureus.64762  \nReview began 06/10/2024  \nReview ended 07/12/2024  \nPublished 07/17/2024  \n© Copyright 2024  \nJamal et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0. , which permits unrestricted use , distribution , and reproduction in any medium , provided the original author and source are credited.  \nReconsidering Routine Histopathological Examination of Gallbladder Specimens in Cholecystectomy: Optimizing Clinical Practice and Resource Management  \nZohaib Jamal 1, Zirong Yu 1 , Nowera Zafar 1, Damon Li 1  \n1. Department of Surgery, Redland Hospital, Bayside Health Service, Redland, AUS Corresponding author: Zohaib Jamal, [drzohaibjamal@gmail.com](drzohaibjamal@gmail.com)  \nAbstract  \nIntroduction  \nCholecystectomy, the surgical removal of the gallbladder, is a common procedure worldwide. Despite no visible anomalies, routine histopathological examination (HPE) of gallbladder specimens post-surgery is standard practice to exclude pathologies, notably gallbladder cancer (GBC) . Incidence rates of GBC vary geographically and ethnically. Surgical intervention is recommended for advanced GBC stages, while early stages may require cholecystectomy alone. Although rare, GBC and bile duct cancers pose increased risks in certain demographics, such as women and individuals over 65. Routine HPE practices vary globally based on resource availability and GBC incidence. This study assesses the necessity of routine HPE by evaluating the selective processing of gallbladder specimens suspected of GBC, prioritizing patient safety.  \nMaterials and methods  \nThis retrospective cohort study conducted at Redland Hospital, a district general hospital in Australia, investigated the necessity of routine HPE for excised gallbladder specimens. Adhering to routine HPE policy, the study encompassed all elective and emergency cholecystectomies performed from January 2023 to December 2023, excluding pediatric cases, concurrent surgical procedures, and those with suspected malignancy. Demographic data, surgery indications, intraoperative findings, histopathological results, and incidental gallbladder cancer (IGC) outcomes were analyzed. Pathology reports and case documentation were reviewed for cancerous pathology indicators.  \nResults  \nOver the one-year study period from January 2023 to December 2023, a total of 266 gallbladder specimens were subjected to HPE post-cholecystectomy. Of these, 201 were female and 65 were male, yielding a maleto-female ratio of 3: 1. Elective cholecystectomy was performed on 56.4%(150) of patients, while 43.6%  \n(116) underwent emergency procedures. Laparoscopic cholecystectomy (LC) was the primary surgical approach, except for one case requiring conversion to an open procedure. None of the patients exhibited GBC; however, 3.3%(9) displayed premalignant histopathological features in their specimens.  \nConclusion  \nIn conclusion, adopting a selective approach, where only gallbladder specimens with macroscopic abnormalities undergo HPE, seems prudent, especially in regions with low GBC incidence. Our study, which revealed no cases of GBC, supports this approach. It not only reduces the risk of missing incidental carcinoma in clinically unsuspected cases but also proves cost-effective and reduces the histopathology department workload without compromising patient outcomes. Therefore, we advocate for routine macroscopic examination of gallbladder specimens for abnormalities before HPE submission, particularly incholecystectomy patients with gallstone disease.  \nCategories: Pathology, Anatomy, General Surgery  \nKeywords: cancer, high-risk, gall bladder, cholecystectomy, histopathology  \nIntroduction  \nCholecystectomy, which is the removal of the gall bladder, is one of the most commonly performed abdominal surgeries throughout the world [1] . Regardless of any readily apparent anomalies, it is a widespread practice t","cbCaikhcBchiPzoK","https://ap.wps.com/l/cbCaikhcBchiPzoK","pdf",270570,"English","# Introduction\n## Background and rationale\n# Materials and methods\n## Study design and inclusion criteria\n## Data collection and pathology review\n# Results\n## Specimen numbers and demographic distribution\n## Operative approach and findings\n# Conclusion\n## Selective HPE recommendation","[{\"question\":\"What were the key findings and what approach is recommended?\",\"answer\":\"Among 266 specimens, no gallbladder cancer cases were found and a small proportion had premalignant features. The study recommends adopting a selective strategy where only specimens with macroscopic abnormalities undergo HPE, especially in regions with low GBC incidence, to reduce workload and costs without compromising outcomes.\"}]","Reconsidering Routine Histopathological Examination of Gallbladder Specimens in Cholecystectomy - Optimizing Clinical Practice and Resource Management | PDF",1789991996,18]