[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-436071-105":59,"doc-detail-436071-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","recent-advances-in-the-diagnosis-and-management-of-acute-myocardial-infarction","Recent advances in the diagnosis and management of acute myocardial infarction","","Recent advances in acute myocardial infarction (AMI) care have been driven by discovery of novel biomarkers for earlier detection, improvements in valid medication options, and percutaneous coronary intervention (PCI), leading to a markedly improved overall prognosis. Persistent clinical challenges still require further work. Emerging diagnostic and therapeutic approaches include new AMI biomarkers, hypothermia therapy, supersaturated oxygen (SSO2) therapy, targeted anti-inflammatory and angiogenesis strategies, and stem cell therapy, aiming to reduce infarct size and avoid myocardial injury–related ventricular remodeling.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/recent-advances-in-the-diagnosis-and-management-of-acute-myocardial-infarction/436071/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/recent-advances-in-the-diagnosis-and-management-of-acute-myocardial-infarction/436071.png","ImageObject",300,407,{"name":92,"@type":93},"Noah","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What causes acute myocardial infarction (AMI) according to the article?","Question",{"text":113,"@type":114},"AMI occurs when a coronary artery plaque ruptures or erodes, forming a blood clot that blocks the artery and reduces blood flow to myocardial cells.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"Which current biomarkers and treatments are discussed for AMI?",{"text":118,"@type":114},"Troponin and creatine kinase are presented as current biomarkers for AMI diagnosis, while percutaneous coronary intervention (PCI) is described as a common approach alongside drug therapies.",{"name":120,"@type":111,"acceptedAnswer":121},"What novel diagnostic and therapeutic techniques are highlighted?",{"text":122,"@type":114},"The review highlights new AMI biomarkers and therapies including hypothermia, supersaturated oxygen (SSO2), targeted anti-inflammatory and angiogenesis strategies, and stem cell therapy, with the goal of reducing infarct size and preventing ventricular remodeling.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},436071,1790779740,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":52,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},8796095462418,"https://ap-avatar.wpscdn.com/avatar/80000253c1241d02b47?x-image-process=image/resize,m_fixed,w_180,h_180&k=1778826106357471780","J Chin MedAssoc  \nReview ARticle  \nRecent advances in the diagnosis and management of acute myocardial infarction  \nYi-Keng Hsieha,b,c, Mei-Tzu Wanga,c, Chien-Ying Wangc,d,e,f, Cheng-Fong Cheng,h,i, Yu-Ling Koj, Wei-Chun Huanga,c,k,*  \naDepartment of Critical Care Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC; bChang Gung Memorial Hospital, Taoyuan, Taiwan, ROC; cSchool of Medicine, National Yang Ming Chao Tung University, Taipei, Taiwan, ROC; dDepartment of Critical Care Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; eDivision of Trauma, Department of Emergency Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; fDepartment of Exercise and Health Sciences, University of Taipei, Taipei, Taiwan, ROC; gDepartment of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; hDepartment of Surgery, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC; iDepartment of Exercise and Health Sciences, University of Taipei, Taipei, Taiwan, ROC; jDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; kDepartment of Physical Therapy, Fooyin University, Kaohsiung, Taiwan, ROC  \nAbstract  \nWith the discovery of new biomarkers for the early detection of acute myocardial infarction (AMI), advancements in valid medication, and percutaneous coronary intervention (PCI), the overall prognosis of AMI has improved remarkably. Nevertheless, challenges remain which require more difficult work to overcome. Novel diagnostic and therapeutic techniques include new AMI biomarkers, hypothermia therapy, supersaturated oxygen (SSO2) therapy, targeted anti-inflammatory therapy, targeted angiogenesis therapy, and stem cell therapy. With these novel methods, we believe that the infarction size after AMI will decrease, and myocardial injury–associated ventricular remodeling may be avoided. This review focuses on novel advances in the diagnosis and management of AMI. Keywords: Diagnosis; Myocardial infarction; Percutaneous coronary intervention; Therapeutics  \n1. INTRODUCTION  \nCardiovascular disease is a leading cause of death worldwide.1–4 Acute myocardial infarction (AMI) occurs when a plaque in a coronary artery ruptures or erodes, causing a blood clot that blocks the artery, leading to reduced blood flow to myocardial cells. This is believed to be a dangerous situation that may lead to death.5–7 Swift detection and medical intervention are vital to restore blood flow and minimize damage. Troponin and creatine kinase are current biomarkers for AMI diagnosis, whereas percutaneous coronary intervention (PCI) is the common approach, alongside drug therapies.2–4,8–16 The AMI-related in-hospital mortality rate has decreased remarkably, but overall improvement in patient outcomes still requires further effort.10,17 Novel biomarkers are being explored with the aim of achieving earlier and more accurate diagnosis of AMI.11,18,19 Hypothermia therapy is considered to have potential benefits in reducing reperfusion injury by reducing the energy demand of myocardial cells.20–24 Supersaturated oxygen (SSO2) therapy shows potential for improving oxygenation and minimize infarction size.25–29 Inflammation targeting methods after AMI have  \n* Address correspondence. Dr. Wei-Chun Huang, Department of Critical Care Medicine, Kaohsiung Veterans General Hospital, 386, Dazhong 1st Road, Kaohsiung 813, Taiwan, [ROC. E-mail address: wchuanglulu@gmail.com](ROC. E-mail address: wchuanglulu@gmail.com) (W.-C. Huang).  \nAuthor Contributions: Dr. Yi-Keng Hsieh and Dr. Mei-Tzu Wang contributed equally to this work.  \nConflicts of interest: The authors declare that they have no conflicts of interest related to the subject matter or materials discussed in this article.  \nJournal of Chinese Medical Association. (2023) 86: 950-959.  \nReceived June 7, 2023; accepted August 30, 2023. doi: 10. 1097/JCMA.0000000000001001  \nCopyright © 2023, the Chinese Med","cbCaimpFtSuptbC0","https://ap.wps.com/l/cbCaimpFtSuptbC0","pdf",468870,"English","# Introduction\n# Epidemiology and demographics of AMI\n# New serum biomarkers for the diagnosis of AMI","[{\"question\":\"What causes acute myocardial infarction (AMI) according to the article?\",\"answer\":\"AMI occurs when a coronary artery plaque ruptures or erodes, forming a blood clot that blocks the artery and reduces blood flow to myocardial cells.\"},{\"question\":\"Which current biomarkers and treatments are discussed for AMI?\",\"answer\":\"Troponin and creatine kinase are presented as current biomarkers for AMI diagnosis, while percutaneous coronary intervention (PCI) is described as a common approach alongside drug therapies.\"},{\"question\":\"What novel diagnostic and therapeutic techniques are highlighted?\",\"answer\":\"The review highlights new AMI biomarkers and therapies including hypothermia, supersaturated oxygen (SSO2), targeted anti-inflammatory and angiogenesis strategies, and stem cell therapy, with the goal of reducing infarct size and preventing ventricular remodeling.\"}]","Recent advances in the diagnosis and management of acute myocardial infarction | PDF",1790676654,25]