[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-377306-105":59,"doc-detail-377306-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","quality-of-life-in-thyroid-cancer-patients-review-article","Quality of Life in Thyroid Cancer Patients - Review article","","Thyroid cancer is among the most prevalent cancers globally and in Saudi Arabia, yet patient quality of life (QoL) had not been specifically assessed in the country. This cross-sectional study evaluated thyroid cancer patients attending outpatient clinics at King Fahad Specialist Hospital (Qassim region) between 2017 and 2023. QoL was measured using the EORTC QLQ-C30 questionnaire, with statistical comparisons via Wilcoxon and Kruskal-Wallis tests. Social functioning scored lowest while cognitive functioning scored highest; fatigue and insomnia were the most severe symptom subscales.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/quality-of-life-in-thyroid-cancer-patients-review-article/377306/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/quality-of-life-in-thyroid-cancer-patients-review-article/377306.png","ImageObject",300,407,{"name":92,"@type":93},"McGucket","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the main aim of the study on thyroid cancer patients’ QoL?","Question",{"text":112,"@type":113},"To assess thyroid cancer patients’ quality of life in Saudi Arabia, addressing the lack of prior country-specific studies.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was quality of life measured and analyzed?",{"text":117,"@type":113},"QoL was measured using the EORTC QLQ-C30 questionnaire through an interviewer-administered approach, and group differences were tested with Wilcoxon and Kruskal-Wallis rank-sum tests.",{"name":119,"@type":110,"acceptedAnswer":120},"Which QoL domains and symptoms showed the highest and lowest scores?",{"text":121,"@type":113},"The lowest functional domain score was social functioning and the highest was cognitive functioning; fatigue and insomnia had the highest symptom subscale scores.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},377306,1790246243,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":52,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},1236954412713,"https://us-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","Open Access Original  \nArticle DOI: 10.7759/cureus.45222  \nReview began 08/18/2023  \nReview ended 09/06/2023  \nPublished 09/14/2023  \n© Copyright 2023  \nAlsaud et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0. , which permits unrestricted use , distribution , and reproduction in any medium , provided the original author and source are credited.  \nQuality of Life in Thyroid Cancer Patients  \nJolan S. Alsaud 1 , Mariam S. Alharbi 1 , Abdullah I. Aldekhail 1 , Rakan A. Almesned 1 , Fatimah S. Alsultan Meshari Alharbi 1 , Hamad Alshubrumi 2  \n1  \n,  \n1. College of Medicine, Qassim University, Buraydah, SAU 2. Endocrinology and Diabetes Center, King Fahad Specialist Hospital, Buraydah, SAU  \nCorresponding author: Jolan S. Alsaud, [jolan.alsaud@gmail.com](jolan.alsaud@gmail.com)  \nAbstract  \nThyroid cancer ranks as the ninth most common cancer worldwide and third in Saudi Arabia. Given thyroid cancer 's high incidence, thyroid cancer patients ' quality of life (QoL) has been a concern for many years. However, no study has been dedicated to assessing thyroid cancer patients ' QoL in Saudi Arabia. Thus, we aimed to fill this gap by assessing thyroid cancer patients ' QoL in Saudi Arabia. This cross-sectional study was conducted among thyroid cancer patients attending outpatient clinics at the Diabetes and Endocrinology Centre, King Fahad Specialist Hospital, Qassim region, Saudi Arabia, from 2017 to 2023. The European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire C30 (EORTCQLQ-C30) assessed the patients ' QoL through an individual interviewer-administered technique. We used RStudio to perform statistical analysis. Statistical differences between groups based on QoL scores were assessed using the Wilcoxon and Kruskal-Wallis rank-sum tests. Our results showed that for QoL scores of functional domains, the lowest was in social functioning, and the highest was in cognitive functioning. Regarding the subscales of symptoms, the highest scores were fatigue and insomnia. In conclusion, numerous factors affect thyroid cancer patients ' QoL. Recognition and appropriate management of these factors will improve the overall QoL; there is a need to understand what is driving these factors in further clinical studies.  \nCategories: Endocrinology/Diabetes/Metabolism, Oncology, Quality Improvement  \nKeywords: quality improvement, thyroid cancer patients, saudi arabia, thyroid cancer, quality of life  \nIntroduction  \nThe World Health Organization (WHO) defines quality of life (QoL) as \"individuals ' perceptions of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards, and concerns \" [1] . The literature interchangeably uses the terms healthrelated quality of life (HRQoL) and QoL. However, several attempts exist to differentiate between these terms to create one general definition and another specific one focusing more on health-related QoL [2] . Moreover, QoL is a multidimensional construct that includes physical, social, psychological, disease, and treatment-related symptoms. One of the proposed and widely accepted definitions of QoL in cancer studies defines it as \"a state of well-being which is a composite of two components: 1) the ability to perform everyday activities that reflect physical, psychological, and social well-being and 2) patient satisfaction with levels of functioning and the control of disease and/or treatment-related symptoms \" [3] . The first component of the state of well-being indicates a more objective aspect of the QoL. By contrast, the second component is more subjective and relies on the patient 's reported satisfaction. The Centers for Disease Control and Prevention (CDC) has defined HRQoL as \"an individual 's or group 's perceived physical and mental health over time.\" Measuring the HRQoL proved its importance and usefulness f","cbCaikoiC8A5g5uY","https://ap.wps.com/l/cbCaikoiC8A5g5uY","pdf",144191,"English","# Abstract\n# Introduction\n## Definition and measurement of QoL/HRQoL\n## Thyroid cancer incidence and relevance in Saudi Arabia","[{\"question\":\"What was the main aim of the study on thyroid cancer patients’ QoL?\",\"answer\":\"To assess thyroid cancer patients’ quality of life in Saudi Arabia, addressing the lack of prior country-specific studies.\"},{\"question\":\"How was quality of life measured and analyzed?\",\"answer\":\"QoL was measured using the EORTC QLQ-C30 questionnaire through an interviewer-administered approach, and group differences were tested with Wilcoxon and Kruskal-Wallis rank-sum tests.\"},{\"question\":\"Which QoL domains and symptoms showed the highest and lowest scores?\",\"answer\":\"The lowest functional domain score was social functioning and the highest was cognitive functioning; fatigue and insomnia had the highest symptom subscale scores.\"}]","Quality of Life in Thyroid Cancer Patients - Review article | PDF",1790224176,25]