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Their classification remains debated, and management ranges from simple appendicectomy to aggressive hyperthermic intraperitoneal chemotherapy (HIPEC). A 42-year-old Chadian man presented with acute right lower abdominal pain, distension, and ascites, with laboratory abnormalities including elevated CEA. Imaging showed extensive ascites and cystic liver and pancreatic lesions; histopathology confirmed pseudomyxoma peritonei of primary appendicular origin, treated with chemotherapy, HIPEC, and resection of involved tissue.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/pseudomyxoma-peritonei-of-appendiceal-mucinous-neoplasm-origin-a-case-report-and-review-of-literature/338281/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/pseudomyxoma-peritonei-of-appendiceal-mucinous-neoplasm-origin-a-case-report-and-review-of-literature/338281.png","ImageObject",300,407,{"name":92,"@type":93},"Rowan","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What characterizes pseudomyxoma peritonei in this condition?","Question",{"text":112,"@type":113},"Pseudomyxoma peritonei is characterized by diffuse intra-abdominal gelatinous collections with mucinous implants, commonly arising from rupture of mucinous tumors, most often appendiceal mucinous neoplasms.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How did the 42-year-old patient initially present?",{"text":117,"@type":113},"The patient presented with sudden right lower abdominal pain radiating to the inguinal region for 24 hours, associated with nausea and vomiting, along with abdominal distension and ascites.",{"name":119,"@type":110,"acceptedAnswer":120},"What treatment approach was used and what determined prognosis?",{"text":121,"@type":113},"Management included chemotherapy and HIPEC followed by removal of affected tissues, with peritoneal and liver nodules submitted for histopathology. Prognosis depended on the grade of the appendiceal tumor and the extent of invasion.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},338281,1790348511,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},1099514067415,"https://ap-avatar.wpscdn.com/avatar/100002539d78ffe74a7?x-image-process=image/resize,m_fixed,w_180,h_180&k=1779092875211072502","Radiology Ca s e Reports 19 (2024) 6565 – 6573  \nAvailable online [at](at www.sciencedirect.com)[ www.sciencedirect.com](at www.sciencedirect.com)  \njournal [homepage:](homepage: www.elsevier.com/locate/radcr)[ www.elsevier.com/locate/radcr](homepage: www.elsevier.com/locate/radcr)  \nCase Report  \nPseudomyxoma peritonei of appendicealmucinous neoplasm origin: A case report and review of literature✩,✩✩  \nAhmed Hafez Mousaa, Houriah Yasir Nukalyb, Rayyan Rafat Sammanb,∗,  \nSamratul Fuadahb, Bushra Wadi Bin Saddiqb, Shahad Jamal Alshowaikhatb, Islam Khalidc  \na Department of Neurosurgery, Graduate Medical Education Department (GME), Mohammed Bin Rashid University  \nof Medicine and Health Sciences (MBRU), Dubai Health, Dubai, United Arab Emirates b College of Medicine and Surgery, Batterjee Medical College, Jeddah, Saudi Arabia c Department of Surgery, Faculty of Medicine, Suez Canal University Hospitals, Ismailia, Egypt  \na r t i c l e i n f o  \nArticle history:  \nReceived 25 May 2024 Revised 28 August 2024 Accepted 29 August 2024  \nKeywords:  \nAppendiceal mucinous neoplasm Appendix cancer Pseudomyxoma peritonei Mucinous adenocarcinoma Case report  \na b s t r a c t  \nAppendiceal mucinous neoplasms, a rarity comprising less than 1% of all cancers, present intricate challenges in clinical management, and their incidence is on the rise. Notably, these neoplasms tend to metastasize intraperitoneally, leading to peritoneal carcinomatosis and concurrent accumulation of mucinous material, resulting in pseudomyxoma peritonei. Due to its spectrum of presentation, the classification of the appendiceal mucinous neoplasms remains a controversial subject with a range of management from a simple appendicectomy to a complex hyperthermic intraperitoneal chemotherapy (HIPEC). A 42-year-old Chadian male presented to the hospital with a sudden onset of right lower abdominal pain radiating to the inguinal region for 24 hours, associated with nausea and vomiting. The abdomen was distended and ascitic. Laboratory investigations revealed anemia, leukocytosis, hypernatremia, hypokalemia, elevated ESR, high CEA marker, and normal CA19-9 . An abdominopelvic CT with contrast demonstrated extensive ascites and cystic masses in the liver, and pancreas with soft tissue thickening of the cecum; however, the appendix is not well-delineated. Patient was managed with chemotherapy and HIPEC followed by removal of all the affected parts. Nodules of the peritoneum and liver were submitted for histopathological analysis and a final diagnosis of pseudomyxoma peritonei of primary appendicular origin was established. This case highlights a case of extensive pseudomyxoma peritonei of appendicular origin managed aggressively by HIPEC and multiple resections of the involved  \n✩ Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.  \n✩✩ Acknowledgments: This paper and the authors did not receive any source of funding to conduct.  \n∗ Corresponding author.  \nE-mail [address:](address: Rayyan.r.samman@gmail.com)[ Rayyan.r.samman@gmail.com](address: Rayyan.r.samman@gmail.com) (R.R. Samman).  \n[https://doi.org/10.1016/j.radcr.2024.08.158](https://doi.org/10.1016/j.radcr.2024.08.158)  \n1930-0433/© 2024 The Authors. Published by Elsevier Inc. on behalf of University of Washington. This is an open access article under the CC BY license ([http://creativecommons.org/licenses/by/4.0/](http://creativecommons.org/licenses/by/4.0/))  \norgans. Prognosis of such a case is determined by the grade of the appendiceal tumor and the extent of invasion.  \n© 2024 The Authors. Published by Elsevier Inc. on behalf of University of Washington.  \nThis is an open access article under the CC BY license  \n([http://creativecommons.org/licenses/by/4.0/](http://creativecommons.org/licenses/by/4.0/))  \nIntroduction  \nAppendiceal Mucinous Neoplasm (AMN) is a rare type of a","cbCaiiOkgZzHRO4P","https://ap.wps.com/l/cbCaiiOkgZzHRO4P","pdf",781976,"English","# Case Report: Pseudomyxoma peritonei of appendiceal mucinous neoplasm origin\n## Abstract\n## Introduction\n## Case presentation\n## Diagnosis and management\n## Histopathological findings\n## Discussion and prognosis","[{\"question\":\"What characterizes pseudomyxoma peritonei in this condition?\",\"answer\":\"Pseudomyxoma peritonei is characterized by diffuse intra-abdominal gelatinous collections with mucinous implants, commonly arising from rupture of mucinous tumors, most often appendiceal mucinous neoplasms.\"},{\"question\":\"How did the 42-year-old patient initially present?\",\"answer\":\"The patient presented with sudden right lower abdominal pain radiating to the inguinal region for 24 hours, associated with nausea and vomiting, along with abdominal distension and ascites.\"},{\"question\":\"What treatment approach was used and what determined prognosis?\",\"answer\":\"Management included chemotherapy and HIPEC followed by removal of affected tissues, with peritoneal and liver nodules submitted for histopathology. Prognosis depended on the grade of the appendiceal tumor and the extent of invasion.\"}]","Pseudomyxoma peritonei of appendiceal mucinous neoplasm origin - A case report and review of literature | PDF",1790022903,23]