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This study retrospectively reviewed seven institutional databases from six Middle Eastern countries to identify patients diagnosed with prostate cancer in 2021. Descriptive analysis characterized demographics, clinical features, and treatment variables, showing late symptomatic presentation and frequent advanced disease at diagnosis.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/prostate-cancer-presentation-and-management-in-the-middle-east/330088/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/prostate-cancer-presentation-and-management-in-the-middle-east/330088.png","ImageObject",300,407,{"name":92,"@type":93},"Himbo","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-22","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":24},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the main goal of the study?","Question",{"text":112,"@type":113},"To provide insights into the initial clinical presentation and management of prostate cancer in the Middle East.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the study conducted?",{"text":117,"@type":113},"A retrospective review was performed using seven institutional databases from Türkiye, Lebanon, Iraq, Syria, Bahrain, and Jordan to identify patients diagnosed in 2021, followed by descriptive analysis.",{"name":119,"@type":110,"acceptedAnswer":120},"What did the results show about how patients were diagnosed?",{"text":121,"@type":113},"Most patients received prostate cancer diagnosis after presenting with symptoms rather than routine PSA screening, and many were diagnosed with advanced-stage disease.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},330088,1790222169,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":24,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},687197100911,"https://ap-avatar.wpscdn.com/avatar/a000239b6f1da00475?x-image-process=image/resize,m_fixed,w_180,h_180&k=1785132997149421697","Sayan et al. BMC Urology (2024) 24:35 [https://doi.org/10.1186/s12894-024-01427-6](https://doi.org/10.1186/s12894-024-01427-6)  \nBMC Urology  \nRESEARCH Open Access  \nProstate cancer presentation and management in the Middle East  \nMutlay Sayan 1,13*, Astrid Langoe2, Ozlem Aynaci3, Ayfer Ay Eren4, Mehmet Fuat Eren5, Il ke Onur Kazaz3, Zainab Ibrahim6, Omar Tama Al-Akelie7, Loma Al-Mansouri8, Ramiz Abu-Hijlih9, Shalini Moningi 1, Elia Abou Chawareb 10, Albert El Hajj 10, Peter F. Orio 1 and Layth Mula-Hussain 11,12  \nAbstract  \nBackground Although prostate cancer is a prevalent malignancy worldwide, its clinical presentation and management in the Middle East are not well-documented. This study aims to provide insights into the initial clinical presentation and management of prostate cancer in this region.  \nMethods A retrospective review was conducted on seven institutional databases from six Middle Eastern countries, including Türkiye, Lebanon, Iraq, Syria, Bahrain, and Jordan, to identify patients diagnosed with prostate cancer in 2021. Descriptive analysis was performed on the collected data to provide an overview of the demographic, clinical, and treatment variables.  \nResults A total of 1,136 patients were identified with a median age of 70 (range, 50–84) . Most patients (78%) received their prostate cancer diagnosis after presenting with symptoms, as opposed to routine PSA screening. At the time of diagnosis, 35% of men had clinical T3 orT4 disease, 54% with Stage IV disease and 50% with Gleason score ≥ 8. Regarding treatment, 20% of non-metastatic and 22% of metastatic patients received no treatment.  \nConclusion Most men in this study sought prostate cancer evaluation due to symptoms and were subsequently diagnosed with advanced-stage disease, providing a foundation for future research aimed at understanding the underlying factors behind the observed trends and enabling informed interventions.  \nKeywords Prostatic neoplasms, Middle East, Disease presentation, Disease management, Diagnostic challenges  \n*Correspondence:  \nMutlay Sayan  \n[msayan@bwh.harvard.edu](msayan@bwh.harvard.edu)  \n1Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA  \n2Boston College, Boston, MA, USA  \n3Karadeniz Technical University, Trabzon, Türkiye, Turkey  \n4Kartal Dr. Lütfi Kirdar Education and Research Hospital, Istanbul, Turkey 5Marmara University, Istanbul Pendik Education and Research Hospital, Istanbul, Türkiye, Turkey  \n6King Hamad University Hospital, Al Sayh, Bahrain  \n7Alamal National Hospital for Cancer Management, Baghdad, Iraq 8Basrah Medical College, Basra, Iraq  \n9King Hussein Cancer Center, Amman, Jordan  \n10American University of Beirut Medical Center, Beirut, Lebanon 11Faculty of Medicine, Dalhousie University, Halifax, NS, Canada 12College of Medicine, Ninevah University, Mosul, Ninevah, Iraq 13Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA  \n© The Author(s) 2024, Corrected publication, March 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit [http://](http://)[ ](http://)[creativecommons.org/l](creativecommons.org/l)ice","cbCaid9miGr38AWR","https://ap.wps.com/l/cbCaid9miGr38AWR","pdf",711662,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusion\n# Background\n## Global context\n## Middle East research gap","[{\"question\":\"What was the main goal of the study?\",\"answer\":\"To provide insights into the initial clinical presentation and management of prostate cancer in the Middle East.\"},{\"question\":\"How was the study conducted?\",\"answer\":\"A retrospective review was performed using seven institutional databases from Türkiye, Lebanon, Iraq, Syria, Bahrain, and Jordan to identify patients diagnosed in 2021, followed by descriptive analysis.\"},{\"question\":\"What did the results show about how patients were diagnosed?\",\"answer\":\"Most patients received prostate cancer diagnosis after presenting with symptoms rather than routine PSA screening, and many were diagnosed with advanced-stage disease.\"}]","Prostate cancer presentation and management in the Middle East | PDF",1789987069,13]