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Among 644 analyzed records, most patients received a perioperative intravenous dose and some received postoperative antibiotics; no culture-positive infections were detected and infection rates were not significantly different between groups. Study concludes withholding postoperative prophylaxis is clinically safe in sterile orbital 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was the purpose of the study regarding antibiotics after surgery?","Question",{"text":61,"@type":62},"To determine the necessity and usefulness of prophylactic postoperative antibiotics for patients undergoing enucleation or ocular evisceration.","Answer",{"name":64,"@type":59,"acceptedAnswer":65},"How were patients grouped and what outcomes were assessed?",{"text":66,"@type":62},"Records were grouped by postoperative antibiotic protocols, and the presence or absence of postoperative wound infection (orbital cellulitis) was recorded and analyzed statistically.",{"name":68,"@type":59,"acceptedAnswer":69},"What did the study find about postoperative infection rates?",{"text":70,"@type":62},"No culture-positive infections were found, and there was no statistically significant difference in postoperative infection rates between patients who received postoperative antibiotics and those who did not.",{"name":72,"@type":59,"acceptedAnswer":73},"What guidance and caution did the authors provide in the conclusions?",{"text":74,"@type":62},"Antibiotics should be discontinued within 24 hours per CDC guidance, and results should not be generalized to nonsterile procedures such as sinonasal or nasolacrimal surgery.","https://schema.org",{"og:url":32,"og:type":77,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":79,"canonical":32},"index,follow",{"doc_id":81,"site_id":7},606491,1792184565,{"code":4,"msg":84,"data":85},"success",[86,90,94,98,103,108,112,117,122,125,129],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":87,"show_sort_weight":88,"slug":89},"Story & 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Evisceration  \nAaron Fay, M.D.*†, Nambi Nallassamy, M.D.†, John D. Pemberton, D.O‡§, Allison Callahan, M.D.*, Edward J. Wladis, M.D ║, John Nguyen, M.D.¶, and Marlene L. Durand, M.D.\\#, For The New England  \nOculoplastics Society Study Group  \n*Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts; †Ophthalmic Plastic and Reconstructive Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts; ‡Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, Arkansas; §Ophthalmic Plastic and Reconstructive Surgery, Jones Eye Institute, Little Rock, Arkansas; ║Ophthalmic Plastic Surgery, Department of Ophthalmology, Lions Eye Institute, Albany Medical College, Albany, New York; ¶Department of Ophthalmology, West Virginia University Medical School, Morgantown, West Virginia; and \\#Department of Medicine, Infectious Disease Unit, Massachusetts General Hospital, Boston, Massachusetts, U.S.A.  \nPurpose: To investigate the necessity and usefulness of prophylactic postoperative antibiotics in patients undergoing enucleation or ocular evisceration.  \nMethods: A retrospective, multicenter, comparative case series was designed. After obtaining Institutional Review Board authorization, a medical records’ review was conducted. Demographics, indication for surgery, surgical technique, postoperative antibiotic dosing, and postoperative course were evaluated. Records were grouped according to antibiotic protocols, and presence or absence of postoperative wound infection (orbital cellulitis) was recorded. Rates of postoperative infection were analyzed statistically.  \nResults: Between 1996 and 2011, 666 evisceration orenucleation surgeries were conducted at 4 institutions. Six hundred forty-eight records were available for analysis, of which 4 were excluded due to insufficient follow-up data. All the remaining 644 patients received a single, perioperative, intravenous dose of antibiotics. Five hundred seventy-eight patients (90%) received an orbital implant, while 66 (10%) did not. Three hundred eighty-one patients (59%) received postoperative antibiotics, and 263 patients (41%) did not. Two cases were identified with signs suggestive of infection, but no culture-positive infections were found, and no patient was admitted to the hospital for management. Of the 2 suspicious cases, 1 was found in the group that received postoperative antibiotics (group 1) and 1 in the group that did not receive postoperative antibiotics (group 2) . No statistically significant  \nAccepted for publication March 04, 2013.  \nThe New England Oculoplastics Study Group: Thomas Bersani, M.D., Scott Corin, M.D., Dawn K. De Castro, M.D., Yoash R. Enzer, M.D., Ioannis Glavas, M.D., Mark P. Hatton, M.D., Jeffrey Hofmann, M.D., Mami Iwamoto, M.D., Natan D. Kahn, M.D., Zachary G. Klett, M.D., John V. Linberg, M.D., John T. Mandeville, M.D., Dale R. Meyer, M.D., Michael E. Migliori, M.D., Sarit Patel, M.D., Philip R. Rizzuto, M.D., Peter A.D. Rubin, M.D., Jennifer A. Sivak-Callcott, M.D., Frank Sutula, M.D., Manoj Thakker, M.D., Daniel J. Townsend, M.D., David Weinberg, M.D., Tory L. Weatherford, M.D.  \nThe authors have no financial or conflicts of interest to disclose.  \nAddress correspondence and reprint requests to Aaron Fay, M.D., Ophthalmic Plastic and Reconstructive Surgery, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114. E-mail: aaron_fay@meei. [harvard.edu](harvard.edu)  \nDOI: 10. 1097/IOP.0b013e3182916674  \ndifference in postoperative infection rate was noted between the 2 groups (p = 0.52) . While patients with infectious indications for surgery were more likely to receive postoperative antibiotics (p \u003C 0.001), there was no statistically significant difference in rates of infection among patients with infectious indications for surgery based on receiving or not receiving postoperative antibiotics (p = 0.79), and no patients wi","cbCaibgyif3RV1Lt","https://ap.wps.com/l/cbCaibgyif3RV1Lt","pdf",256926,"English","# Purpose\n# Methods\n# Results\n# Conclusions\n# Background and Rationale","[{\"question\":\"What was the purpose of the study regarding antibiotics after surgery?\",\"answer\":\"To determine the necessity and usefulness of prophylactic postoperative antibiotics for patients undergoing enucleation or ocular evisceration.\"},{\"question\":\"How were patients grouped and what outcomes were assessed?\",\"answer\":\"Records were grouped by postoperative antibiotic protocols, and the presence or absence of postoperative wound infection (orbital cellulitis) was recorded and analyzed statistically.\"},{\"question\":\"What did the study find about postoperative infection rates?\",\"answer\":\"No culture-positive infections were found, and there was no statistically significant difference in postoperative infection rates between patients who received postoperative antibiotics and those who did not.\"},{\"question\":\"What guidance and caution did the authors provide in the conclusions?\",\"answer\":\"Antibiotics should be discontinued within 24 hours per CDC guidance, and results should not be generalized to nonsterile procedures such as sinonasal or nasolacrimal surgery.\"}]","Prophylactic Postoperative Antibiotics for Enucleation and Evisceration | PDF",13]