[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-377392-105":59,"doc-detail-377392-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","progress-and-perspectives-in-colon-cancer-pathology-diagnosis-and-treatments","Progress and Perspectives in Colon Cancer Pathology, Diagnosis, and Treatments","","Worldwide, colon cancer is among the most prevalent malignancies and a leading cause of cancer death. Although it can occur at any age, risk is highest in older adults, often starting from benign polyp-like cell clusters that may progress to malignant tissue if untreated. Diagnosis relies on routine examination and techniques such as colonoscopy and imaging, followed by polyp removal. When malignancy develops, care may involve surgery, chemotherapy, targeted therapy, and immunotherapy.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/progress-and-perspectives-in-colon-cancer-pathology-diagnosis-and-treatments/377392/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/progress-and-perspectives-in-colon-cancer-pathology-diagnosis-and-treatments/377392.png","ImageObject",300,407,{"name":92,"@type":93},"Mary Man","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-27","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",12,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Where does colon cancer commonly begin?","Question",{"text":113,"@type":114},"Colon cancer growth often begins in the colon with small non-cancerous cell clusters known as polyps.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How is colon cancer diagnosed?",{"text":118,"@type":114},"Diagnosis uses routine inspection and techniques including colonoscopy and cancer scanning to identify polyps and suspicious changes.",{"name":120,"@type":111,"acceptedAnswer":121},"What treatment strategies are used when polyps become malignant?",{"text":122,"@type":114},"Treatment strategies can include surgery, chemotherapy, targeted therapy, and immunotherapy, tailored to the patient’s condition.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},377392,1791830108,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":146},7421720224475,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","diseases   \nReview  \nProgress and Perspectives in Colon Cancer Pathology, Diagnosis, and Treatments  \nNoor Alrushaid 1,2, Firdos Alam Khan 2, Ebtesam Al-Suhaimi 3 and Abdelhamid Elaissari 1, *  \nCitation: Alrushaid, N.; Khan, F.A.; Al-Suhaimi, E.; Elaissari, A. Progress and Perspectives in Colon Cancer Pathology, Diagnosis, and Treatments. Diseases 2023, 11, 148 .  \n[https://doi.org/10.3390/](https://doi.org/10.3390/)[ ](https://doi.org/10.3390/)diseases11040148  \nAcademic Editors: Veysel Tahan and Antoine Adenis  \nReceived: 31 July 2023  \nRevised: 3 September 2023  \nAccepted: 17 October 2023  \nPublished: 24 October 2023  \nCopyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ([https://](https://)[ ](https://)[creativecommons.org/licenses/by/](creativecommons.org/licenses/by/)[ ](creativecommons.org/licenses/by/)[4.0/](4.0/)) .  \n1 Universite Claude Bernard Lyon-1, CNRS, ISA-UMR 5280, 69100 Villeurbanne, France; [naalrushaid@iau.edu.sa](naalrushaid@iau.edu.sa)  \n2 Department of Stem Cell Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia; [fakhan@iau.edu.sa](fakhan@iau.edu.sa)  \n[3](3 Biology Department)[ Biology Department](3 Biology Department), [College of Science](College of Science), [Institute of Research & Medical Consultations](Institute of Research & Medical Consultations) ([IRMC](IRMC)), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia; [ealsuhaimi@iau.edu.sa](ealsuhaimi@iau.edu.sa)  \n* Correspondence: [abdelhamid.elaissari@univ-lyon1.fr](abdelhamid.elaissari@univ-lyon1.fr)  \nAbstract: Worldwide, colon cancer is the third most frequent malignancy and the second most common cause of death. Although it can strike anybody at any age, colon cancer mostly affects the elderly. Small, non-cancerous cell clusters inside the colon, commonly known as polyps, are typically where colon cancer growth starts. But over time, if left untreated, these benign polyps may develop into malignant tissues and develop into colon cancer. For the diagnosis of colon cancer, with routine inspection of the colon region for polyps, several techniques, including colonoscopy and cancer scanning, are used. In the case identifying the polyps in the colon area, efforts are being taken to surgically remove the polyps as quickly as possible before they become malignant. If the polyps become malignant, then colon cancer treatment strategies, such as surgery, chemotherapy, targeted therapy, and immunotherapy, are applied to the patients. Despite the recent improvements in diagnosis and prognosis, the treatment of colorectal cancer (CRC) remains a challenging task. The objective of this review was to discuss how CRC is initiated, and its various developmental stages, pathophysiology, and risk factors, and also to explore the current state of colorectal cancer diagnosis and treatment, as well as recent advancements in the field, such as new screening methods and targeted therapies. We examined the limitations of current methods and discussed the ongoing need for research and development in this area. While this topic may be serious and complex, we hope to engage and inform our audience on this important issue.  \nKeywords: colorectal cancer; development of colorectal cancer; colorectal cancer pathology; colorectal cancer diagnosis; molecular markers; cancer treatments  \n1. Introduction  \nAmong different types of cancer, colorectal cancer (CRC) is classified as the third most commonly reported cancer after breast and lung cancers and is ranked as the second most common cause of cancer death [1] . CRC is more frequently diagnosed in males than in females [2] . It could be in the colon, anus, or rectum; all these distinct cancer types are indicated as either colon or colorectal cancer. As per the International Agency ","cbCaic6Nrm65MuH2","https://ap.wps.com/l/cbCaic6Nrm65MuH2","pdf",4179263,22,"English","# Abstract\n# Keywords\n# 1. Introduction","[{\"question\":\"Where does colon cancer commonly begin?\",\"answer\":\"Colon cancer growth often begins in the colon with small non-cancerous cell clusters known as polyps.\"},{\"question\":\"How is colon cancer diagnosed?\",\"answer\":\"Diagnosis uses routine inspection and techniques including colonoscopy and cancer scanning to identify polyps and suspicious changes.\"},{\"question\":\"What treatment strategies are used when polyps become malignant?\",\"answer\":\"Treatment strategies can include surgery, chemotherapy, targeted therapy, and immunotherapy, tailored to the patient’s condition.\"}]","Progress and Perspectives in Colon Cancer Pathology, Diagnosis, and Treatments | PDF",1790224736,55]