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Yet Canada faces an accelerating rise, with incidence increasing by 3.7% per year since 2015 (2023 data). HPV vaccination and cervical screening are central to WHO and CPAC elimination targets for 2030 and 2040, including higher vaccine uptake, primary HPV screening, and improved follow-up. Progress is constrained by incomplete vaccination coverage (47%–81%, completion ~64% vs 90% target), slow provincial adoption of HPV DNA testing outside select regions, and insufficient transparency and coordination. The article reviews current Canadian HPV prevention strategies and outlines recommendations to overcome barriers through standardized guidelines, education, partnerships, task forces, and resource sharing among stakeholders.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/progress-and-challenges-in-canadas-path-toward-the-elimination-of-cervical-cancer/340301/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/progress-and-challenges-in-canadas-path-toward-the-elimination-of-cervical-cancer/340301.png","ImageObject",300,407,{"name":92,"@type":93},"Skyler","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-22",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why is cervical cancer considered eliminable in Canada and worldwide?","Question",{"text":112,"@type":113},"Cervical cancer is almost entirely preventable and treatable when detected early. The article defines elimination as 4 or fewer cases per 100,000 annually.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What prevention measures are central to Canada’s elimination targets?",{"text":117,"@type":113},"HPV vaccination and cervical screening are identified as the key primary and secondary prevention measures. 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Progress and Challenges in Canada’s Path Toward the Elimination of Cervical Cancer. Curr. Oncol. 2024, 31, 5850–5861 . [https://doi.org/10.3390/](https://doi.org/10.3390/)[ ](https://doi.org/10.3390/)curroncol31100435  \nReceived: 10 July 2024  \nRevised: 19 September 2024  \nAccepted: 27 September 2024  \nPublished: 29 September 2024  \nCopyright: © 2024 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ([https://](https://)[ ](https://)[creativecommons.org/licenses/by/](creativecommons.org/licenses/by/)[ ](creativecommons.org/licenses/by/)[4.0/](4.0/)) .  \n1 Department of Oncology, Faculty of Medicine and Health Sciences, McGill University, Montréal, QC H4A 3T2, Canada; [samara.perez@mcgill.ca](samara.perez@mcgill.ca)  \n2 Research Institute of McGill University Health Centre, Montréal, QC H4A 3J1, Canada  \n3 Psychosocial Oncology Program, Cedars Cancer Centre, Division of Supportive & Palliative Care, McGill University Health Centre, Montréal, QC H4A 3J1, Canada  \nAbstract: Cervical cancer is almost entirely preventable and treatable when detected early, making its elimination within reach for Canada and the world. However, cervical cancer is now the fastestincreasing cancer (+3.7% per year since 2015) in Canada as of 2023, marking the first significant increase in cervical cancer incidence since 1984 . The human papillomavirus (HPV) vaccine and cervical screening are key preventive measures, with targets set by the WHO and the Canadian Partnership Against Cancer (CPAC) to eliminate cervical cancer in Canada by 2030 and 2040, respectively. These targets include increasing HPV vaccination rates, implementing primary HPV screening, and improving follow-up for abnormal HPV+ results. However, Canada’s progress has been impeded by significant challenges. As of the most recent data, HPV vaccine coverage rates in Canada range from 47% to 81%, with an estimated national HPV vaccination completion rate of 64% in Canada, far below the target of 90% by 2025 set by the CPAC. With the exception of British Columbia and Prince Edward Island, the adoption of HPV DNA testing as the primary screening method has been slow across the Canadian provinces and territories despite its superior sensitivity compared with traditional cytology. This article reviews the current state of HPV vaccination and screening in Canada, emphasizing the need for coordinated efforts, transparency, and resource sharing to overcome barriers. Key recommendations include the dissemination of accessible educational materials, partnerships, and collaboration, including nationwide task forces and roundtables, and the implementation of standardized guidelines for HPV screening. Achieving cervical cancer elimination requires a united approach involving federal, provincial, and territorial health authorities, researchers, clinicians, NGOs, community groups, and patients’ voices working together to ensure consistent, effective, timely, and meaningful cervical cancer prevention strategies are used across the country.  \nKeywords: cervical cancer elimination; human papillomavirus; HPV vaccination; cervical screening; Canada; HPV DNA testing; vaccine coverage; public health strategy; cancer prevention; health disparities  \n1. Introduction  \nCervical cancer is almost entirely preventable and treatable when detected early. As such, cervical cancer can be eliminated (defined as 4 or fewer cases per 100,000 annually) in Canada and worldwide. The human papillomavirus (HPV) vaccine and cervical screening are safe and effective primary and secondary prevention measures, respectively, for HPVrelated diseases associated with HPV [1] . HPV can cause cervical, head and neck, vaginal, vulvar, anal, and penile cancers, as well as gen","cbCaiof319ZXVhmI","https://ap.wps.com/l/cbCaiof319ZXVhmI","pdf",455014,12,"English","# Introduction\n## HPV prevention: vaccination and screening\n## Canada’s cervical screening organization\n# Progress toward elimination and remaining barriers\n## HPV vaccination coverage and targets\n## Adoption of HPV DNA testing across provinces\n## Standardized guidelines and coordinated stakeholder action","[{\"question\":\"Why is cervical cancer considered eliminable in Canada and worldwide?\",\"answer\":\"Cervical cancer is almost entirely preventable and treatable when detected early. The article defines elimination as 4 or fewer cases per 100,000 annually.\"},{\"question\":\"What prevention measures are central to Canada’s elimination targets?\",\"answer\":\"HPV vaccination and cervical screening are identified as the key primary and secondary prevention measures. The targets emphasize increasing vaccination rates, moving to primary HPV screening, and improving follow-up for abnormal HPV-positive results.\"},{\"question\":\"What challenges slow progress in Canada’s cervical cancer elimination efforts?\",\"answer\":\"Challenges include incomplete HPV vaccine coverage (47%–81% and ~64% completion nationally vs a 90% target) and slow uptake of HPV DNA testing as the primary screening method in most provinces and territories.\"}]","Progress and Challenges in Canada’s Path Toward the Elimination of Cervical Cancer | PDF",1790035598]