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This prospective study analyzed associations between emergency department findings at admission and outcomes in severely injured adult patients presenting within 24 hours. Data included clinical and imaging findings, serum procalcitonin levels, ICU and hospital stay, infection incidence, and discharge or death. Results showed mortality was associated with injury severity and neurologic status, while admission procalcitonin lacked predictive value for death, bloodstream infections, infectious complications, or ICU length.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/procalcitonin-assay-has-no-role-in-the-routine-assessment-of-severe-trauma-patients-at-admission-to-the-emergency-department/506428/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/procalcitonin-assay-has-no-role-in-the-routine-assessment-of-severe-trauma-patients-at-admission-to-the-emergency-department/506428.png","ImageObject",300,407,{"name":92,"@type":93},"Well Done","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-10","2026-10-05",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",12,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What was the main purpose of assessing procalcitonin at admission?","Question",{"text":113,"@type":114},"The study examined whether serum procalcitonin (PCT) levels at emergency department admission predict mortality and infectious outcomes in severely trauma patients.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"Which factors were significantly associated with mortality in severe trauma patients?",{"text":118,"@type":114},"Injury severity and neurologic status were key: Injury Severity Score (ISS) >25 and Glasgow Coma Scale (GCS) \u003C8, along with head and neck and extremity injuries.",{"name":120,"@type":111,"acceptedAnswer":121},"Did admission procalcitonin predict death or infection outcomes?",{"text":122,"@type":114},"No. PCT levels at admission had no significant predictive value for mortality, bloodstream infections, other infectious complications, or length of ICU stay.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},506428,1791291790,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":29,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},5909892210082,"https://ap-avatar.wpscdn.com/avatar/56001069da27c9f41e8?x-image-process=image/resize,m_fixed,w_180,h_180&k=1789614185077863061","Open Access Original  \nArticle DOI: 10.7759/cureus.16228  \nReview began 06/27/2021  \nReview ended 06/28/2021  \nPublished 07/07/2021  \n© Copyright 2021  \nLakshmi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.  \nProcalcitonin Assay Has No Role in the Routine Assessment of Severe Trauma Patients at Admission to the Emergency Department  \nVijaya S. Lakshmi 1 , Anusha Cherian 2 , Prashant Adole 3  \n1. Emergency Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, IND 2. Anaesthesiology and Critical Care, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, IND 3. Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, IND  \nCorresponding author: Anusha Cherian, [anushacherian@gmail.com](anushacherian@gmail.com)  \nAbstract  \nIntroduction  \nA key challenge in emergency departments (ED) is the early recognition of sepsis or the potential for sepsis in patients. Appropriate and accurate ED triage will ensure improved case management. This study analysed the association between ED findings at admission and outcomes in patients presenting with severe trauma.  \nMethods  \nThis was a prospective study conducted at a tertiary level ED and included severely injured adult patients who presented to the ED within 24 hours of injury. Data collected included clinical findings and imaging reports at initial assessment, serum procalcitonin (PCT), length of ICU and hospital stay, the incidence of bloodstream and other infections, and patient outcome as discharge from care or death. Multiple logistic regression was used to assess the association between outcome variables and independent variables.  \nResults  \nA total of 155 patients were included in the study. Head and neck (61 .9%), extremity (58%), and chest (45%) were more commonly injured. Injury Severity Score (ISS) >25, Glasgow Coma Scale (GCS) score \u003C8, head and neck injuries, and extremity injuries were found to be significantly associated with mortality. Bloodstream infections were more common in the presence of lung contusions, abdominal injury, operative management, and blood transfusions. PCT levels at admission did not have a significant predictive value for mortality, bloodstream infections, other infectious complications, or length of ICU stay.  \nConclusions  \nHead injuries were the most common cause of mortality in our study. In addition to the anatomical region involved, ISS and GCS have a significant association with mortality. PCT levels at ED admission do not have any prognostic value and need not be routinely analysed.  \nCategories: Anesthesiology, Emergency Medicine  \nKeywords: trauma, triage, head injury, mortality, sepsis, procalcitonin, injury severity score  \nIntroduction  \nRoad traffic accidents (RTAs) contribute significantly to preventable death and illness globally. According to the WHO Global Status Report on Road Safety 2018, 1.35 million people lose their lives every year, and 20 to 50 million people get injured from RTAs. RTAs rank among the first five causes of morbidity and mortality in Southeast Asian countries. In India, an accident occurs every one minute, and a death every 3.7 minutes, amounting to more than 3. 7% loss of national GDP. There has been a marked increase in the social and economic burden due to RTA in recent years [1,2] .  \nPolytrauma patients require prolonged hospital care and are especially prone to inflammatory response syndrome and infectious complications. Despite recent medical advances, morbidity and mortality in severe trauma patients due to sepsis continue to remain high. A key challenge in emergency departments (ED) is the early recognition of the potential for or manifestation of sepsis.  \nAppropriate and accurate ED triage wil","cbCaikBdvOzXk0pl","https://ap.wps.com/l/cbCaikBdvOzXk0pl","pdf",116958,"English","# Introduction\n# Methods\n# Results\n# Conclusions\n# Materials And Methods\n## Study setting and participants\n## Data collection and outcomes\n## Procalcitonin assay","[{\"question\":\"What was the main purpose of assessing procalcitonin at admission?\",\"answer\":\"The study examined whether serum procalcitonin (PCT) levels at emergency department admission predict mortality and infectious outcomes in severely trauma patients.\"},{\"question\":\"Which factors were significantly associated with mortality in severe trauma patients?\",\"answer\":\"Injury severity and neurologic status were key: Injury Severity Score (ISS) \\u003e25 and Glasgow Coma Scale (GCS) \\u003c8, along with head and neck and extremity injuries.\"},{\"question\":\"Did admission procalcitonin predict death or infection outcomes?\",\"answer\":\"No. PCT levels at admission had no significant predictive value for mortality, bloodstream infections, other infectious complications, or length of ICU stay.\"}]","Procalcitonin Assay Has No Role in the Routine Assessment of Severe Trauma Patients at Admission to the Emergency Department | PDF",1791165220,15]