[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-336420-105":59,"doc-detail-336420-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","primary-adenocarcinoma-of-the-renal-pelvis-an-uncommon-tumor-a-case-report","Primary adenocarcinoma of the renal pelvis - An uncommon tumor - a case report","","Primary adenocarcinoma of the renal pelvis is a rare, distinct malignancy that accounts for a small fraction of renal cancers and creates major diagnostic difficulties. A 34-year-old man with persistent lower back pain but no hematuria showed a 30×14 mm enhancing mass on imaging. Diagnosis was confirmed after right nephroureterectomy with bladder cuff excision, with histopathology supporting intestinal-type adenocarcinoma and occasional signet ring cells. Immunohistochemistry and comprehensive histopathological review helped differentiate this rare origin from urothelial or metastatic digestive adenocarcinoma.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/primary-adenocarcinoma-of-the-renal-pelvis-an-uncommon-tumor-a-case-report/336420/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/primary-adenocarcinoma-of-the-renal-pelvis-an-uncommon-tumor-a-case-report/336420.png","ImageObject",300,407,{"name":92,"@type":93},"Maeve","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why is primary adenocarcinoma of the renal pelvis difficult to diagnose?","Question",{"text":112,"@type":113},"Its symptoms are nonspecific and often resemble more common upper excretory tract disorders, which can mislead clinicians and delay accurate identification.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What were the patient’s key presenting features and imaging findings?",{"text":117,"@type":113},"The patient had persistent lower back pain for several months without hematuria. CT identified a 30×14 mm enhancing mass in the right renal pelvis after iodinated contrast.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the definitive diagnosis established in this case?",{"text":121,"@type":113},"A right nephroureterectomy with excision of the bladder cuff was performed, and histopathological examination confirmed intestinal-type primary adenocarcinoma, supported by immunohistochemical findings.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},336420,1790120895,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":19,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":52},5909877438554,"https://ap-avatar.wpscdn.com/avatar/5600025385ad2bf12a7?_k=1778553567797529272","International Journal of Surgery Case Reports 120 (2024) 109887  \nContents lists available at ScienceDirect  \nInternational Journal of Surgery Case Reports  \njournal [homepage:](homepage: www.elsevier.com/locate/ijscr)[ www.elsevier.com/locate/ijscr](homepage: www.elsevier.com/locate/ijscr)  \n| Case report\u003Cbr>Primary adenocarcinoma of the renal pelvis: An uncommon tumor, a case report\u003Cbr>Wael Gazzah a, * , Mahdy Mzoughia , Rayen Lahouara , Badreddine Benkhalifa a , Bacem Zaidib, Braiek Salema\u003Cbr>a University of Sousse, faculty of Medicine, Department of Urology, Ibn El Jazzar Hospital, Kairouan, Tunisia b University of Sousse, Faculty of Medicine, Department of Surgery, Ibn El Jazzar Hospital, Kairouan, Tunisia |  |  |\n| --- | --- | --- |\n| A R T I C L E I N F O |  | A B S T R A C T |\n| Keywords: Adenocarcinoma Renal pelvis neoplasms Nephroureterectomy Diagnostic imaging Urology |  | Introduction and importance: Primary adenocarcinoma of the renal pelvis is a rare and unique malignancy, representing a small fraction of renal cancers and posing significant diagnostic challenges due to its unusual presentation and similarity in symptoms to more common excretory tract disorders. This case emphasizes the importance of distinguishing this pathology from other renal neoplasms and metastatic adenocarcinomas that originate in the digestive tract.\u003Cbr>Case presentation: We report the case of a 34-year-old man with no significant medical history who presented persistent lower back pain but no hematuria, which is atypical for renal pathologies. Initial imaging identified a 30 × 14 mm enhancement mass in the right renal pelvis. Surgical intervention was performed through right nephroureterectomy, including excision of the bladder cuff. Histopathological examination confirmed the diagnosis of primary intestinal-type adenocarcinoma of the renal pelvis, characterized by necrotic carcinomatous proliferation with varying architectural patterns and occasional signet ring cells.\u003Cbr>Clinical discussion: The diagnosis of primary renal pelvis adenocarcinoma is complicated by its nonspecific symptomatology and the potential for misdiagnosis as a more common urothelial carcinoma or a metastatic digestive-origin adenocarcinoma. Immunohistochemical staining supported a primary rather than metastatic digestive tract origin. This case underscores the need for a comprehensive diagnostic approach, including advanced imaging and meticulous histopathological analysis, to effectively differentiate this rare entity from other neoplasms.\u003Cbr>Conclusions: This case highlights the diagnostic complexities and the critical need to be aware among clinicians about rare renal cancers such as primary adenocarcinoma of the renal pelvis. It also stresses the importance of interdisciplinary collaboration in the diagnosis and management of such rare cases, improving our understanding and requiring timely and accurate treatment. |\n\n1. Introduction  \nPrimary adenocarcinoma of the kidney pelvis is a highly unusual and under-documented cancer, representing a small fraction of urological tumors [1]. Originating uniquely within the renal pelvis, this form of cancer is not only rare, but also distinct in its clinical presentation and pathological characteristics, which differ markedly from the more prevalent urothelial carcinoma [2].  \nThe diagnosis of primary renal pelvis adenocarcinoma is notoriously challenging due to its symptomatology, which often mirrors that ofmore common disorders ofthe upper excretory tract. This overlap can mislead  \nclinicians and delay an accurate diagnosis, underscoring the need for increased awareness and precise investigative procedures [3].  \nTo illustrate these complexities, we present the case of a 34-year-oldman initially treated for an upper urinary tract tumor. Despite initial interventions, the definitive diagnosis of intestinal-type primary adenocarcinoma of the renal pelvis was only confirmed by a complete histopathological analysis after a ","cbCaiqfXKn0xOXJ8","https://ap.wps.com/l/cbCaiqfXKn0xOXJ8","pdf",1176537,"English","# Introduction\n# Patient and observation\n## Presentation and diagnosis\n## Surgical intervention\n## Pathological examination","[{\"question\":\"Why is primary adenocarcinoma of the renal pelvis difficult to diagnose?\",\"answer\":\"Its symptoms are nonspecific and often resemble more common upper excretory tract disorders, which can mislead clinicians and delay accurate identification.\"},{\"question\":\"What were the patient’s key presenting features and imaging findings?\",\"answer\":\"The patient had persistent lower back pain for several months without hematuria. CT identified a 30×14 mm enhancing mass in the right renal pelvis after iodinated contrast.\"},{\"question\":\"How was the definitive diagnosis established in this case?\",\"answer\":\"A right nephroureterectomy with excision of the bladder cuff was performed, and histopathological examination confirmed intestinal-type primary adenocarcinoma, supported by immunohistochemical findings.\"}]","Primary adenocarcinoma of the renal pelvis - An uncommon tumor - a case report | PDF",1790014960]