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This case report describes a 21-year-old patient with cerebral palsy presenting with priapism for 13 hours and a prior spontaneous episode one month earlier. Ischemic priapism was confirmed by aspiration and blood gas analysis, while extreme leukocytosis led to hematology evaluation, smear diagnosis of chronic myeloid leukemia, and urgent leukapheresis. After normalization of white blood cell count, detumescence occurred and no further episodes were reported.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/priapism-as-the-initial-presentation-of-chronic-myeloid-leukemia-in-a-patient-with-cerebral-palsy-a-case-report/456601/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/priapism-as-the-initial-presentation-of-chronic-myeloid-leukemia-in-a-patient-with-cerebral-palsy-a-case-report/456601.png","ImageObject",300,407,{"name":92,"@type":93},"ahduag","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-28","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":19},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"How was ischemic priapism diagnosed in this case?","Question",{"text":112,"@type":113},"A venous catheter was inserted into the corpus cavernosum, dark blood was aspirated, and blood gas analysis confirmed ischemic priapism. Priapism persisted, requiring further catheterization and irrigation with normal saline plus epinephrine.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What led to the diagnosis of chronic myeloid leukemia (CML)?",{"text":117,"@type":113},"Marked leukocytosis prompted referral to hematology. Peripheral blood smear analysis confirmed CML, and emergency leukapheresis was performed.",{"name":119,"@type":110,"acceptedAnswer":120},"What treatment outcome was achieved after leukapheresis?",{"text":121,"@type":113},"Following normalization of the peripheral white blood cell count, penile detumescence was achieved. No further episodes of priapism occurred.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},456601,1791188340,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":19,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":81,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":39,"preview_page_count":4},3985747870414,"https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc","CASE REPORT  \nPriapism as the initial presentation of chronic myeloid leukemia in a patient with cerebral palsy: A case report  \n Emre Hepsen,1  Kubilay Sarıkaya1  \nClinic of Urology, Ankara Etlik City Hospital, Ankara-Türkiye  \nABSTRACT  \nPriapism is defined as a penile erection lasting more than four hours without stimulation. The majority of cases involve ischemic priapism, in which there is partial or complete absence of cavernosal arterial flow. Priapism is uncommon, with an estimated annual incidence of approximately 1.5 cases per 100,000 men. In chronic myeloid leukemia (CML) patients, leukostasis may occur, which can lead to priapism in 1-2% of cases. We present the case of a 21-year-old patient with a history of cerebral palsy who was brought to the emergency department by his family with priapism persisting for 13 hours. It was noted that the patient had experienced one prior episode of priapism a month earlier, which had resolved spontaneously. He had no history of trauma. On physical examination, extremity contractures related to cerebral palsy were noted, and the penis was observed to be erect. A venous catheter was inserted into the corpus cavernosum, dark-colored blood was aspirated, and blood gas analysis confirmed the diagnosis of ischemic priapism. The corpus cavernosum was irrigated with normal saline, and epinephrine was administered into both corpora cavernosa; however, priapism did not resolve. Laboratory tests revealed a white blood cell count of 581,760 /mm³. The patient was referred to the hematology department. Peripheral blood smear analysis confirmed the diagnosis of CML, and leukapheresis was performed three times within two days. Following normalization of the peripheral white blood cell count, penile detumescence was achieved, and no further episodes of priapism occurred. In conclusion, early diagnosis and a multidisciplinary approach improve the success of priapism treatment and reduce the risk of complications.  \nKeywords: Priapism; chronic myeloid leukemia; leukostasis.  \nINTRODUCTION  \nPriapism is defined as a penile erection lasting more than four hours without stimulation. The majority of cases involve ischemic priapism, in which there is partial or complete absence of cavernosal arterial flow. In ischemic priapism, metabolic changes occur due to hypoxia, hypercapnia, and acidosis, with patients typically experiencing pain after 6-8 hours.[1]  \nPriapism is an uncommon condition, with an estimated annual incidence of approximately 1.5 cases per 100,000 men. Hematologic disorders account for 20% of priapism cases in males, with sickle cell anemia being the most common cause. Additionally, priapism due to venous occlusion has been reported  \nin 1-5% of male leukemia patients, with chronic myeloid leukemia (CML) representing 50% of these cases.[2,3]  \nThis case report presents a 21-year-old patient with cerebral palsy who was diagnosed with CML following the presentation of priapism.  \nCASE REPORT  \nA 21-year-old male patient with a history of cerebral palsyassociated intellectual disability and epilepsy, controlled with antiepileptic medications, was brought to the emergency department by his family with priapism persisting for 13 hours. The family reported that the patient had experienced  \n\n| Cite this article as: Hepsen E, Sarıkaya K. Priapism as the initial presentation of chronic myeloid leukemia in a patient with cerebral palsy: A case report. Ulus Travma Acil Cerrahi Derg 2025;31:1065-1067.\u003Cbr>Address for correspondence: Emre Hepsen\u003Cbr>Clinic of Urology, Ankara Etlik City Hospital, Ankara, Türkiye\u003Cbr>E-mail: [dremrehepsen@gmail.com](dremrehepsen@gmail.com) |  |  |\n| --- | --- | --- |\n| Ulus Travma Acil Cerrahi Derg 2025;31(10):1065-1067 DOI: 10.14744/tjtes.2025.06464 Submitted: 12.05.2025 Revised: 20.07.2025 Accepted: 03.08.2025 Published: 07.10.2025\u003Cbr>OPEN ACCESS This is an open access article under the CC BY-NC license ([http://creativecommons.org/licenses/by-nc/4.0/](http://creative","cbCaifC3P3aEevUV","https://ap.wps.com/l/cbCaifC3P3aEevUV","pdf",544899,"English","# Abstract\n# Introduction\n# Case report","[{\"question\":\"How was ischemic priapism diagnosed in this case?\",\"answer\":\"A venous catheter was inserted into the corpus cavernosum, dark blood was aspirated, and blood gas analysis confirmed ischemic priapism. Priapism persisted, requiring further catheterization and irrigation with normal saline plus epinephrine.\"},{\"question\":\"What led to the diagnosis of chronic myeloid leukemia (CML)?\",\"answer\":\"Marked leukocytosis prompted referral to hematology. Peripheral blood smear analysis confirmed CML, and emergency leukapheresis was performed.\"},{\"question\":\"What treatment outcome was achieved after leukapheresis?\",\"answer\":\"Following normalization of the peripheral white blood cell count, penile detumescence was achieved. No further episodes of priapism occurred.\"}]","Priapism as the Initial Presentation of Chronic Myeloid Leukemia in a Patient with Cerebral Palsy - A Case Report | PDF",1790746482]