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Primary endpoints include operative time, clinical and radiological hernia, and complications graded by Clavien-Dindo. Three randomized controlled trials (n=782) show reduced clinical PSH with mesh (RR 0.50, p\u003C0.002) but no significant change in radiological PSH (RR 0.72, p=0.10) or complication rates.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/prevention-of-parastomal-hernia-after-ileal-conduit-using-prophylactic-mesh-a-meta-analysis-of-randomized-controlled-trials/449346/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/prevention-of-parastomal-hernia-after-ileal-conduit-using-prophylactic-mesh-a-meta-analysis-of-randomized-controlled-trials/449346.png","ImageObject",300,407,{"name":92,"@type":93},"Bulrr","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-05","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",12,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What was the purpose of this study?","Question",{"text":113,"@type":114},"To assess the effectiveness of prophylactic mesh in preventing parastomal hernia after cystectomy and ileal conduit.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How were the outcomes evaluated in the meta-analysis?",{"text":118,"@type":114},"Outcomes included operation time, clinical hernia, radiological hernia, and complications categorized by Clavien-Dindo grade.",{"name":120,"@type":111,"acceptedAnswer":121},"Does prophylactic mesh reduce complications or only clinical PSH?",{"text":122,"@type":114},"Mesh significantly reduces clinical PSH incidence, but it does not significantly affect radiological hernia rates or overall complication rates.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},449346,1790792278,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":39,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":46,"preview_page_count":4},5909892115043,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","ARAB JOURNAL OF UROLOGY 2026, VOL. 24, NO. 1, 82–89  \n[https://doi.org/10.1080/20905998.2025.2526980](https://doi.org/10.1080/20905998.2025.2526980)  \n| \u003Cbr>Prevention of parastomal hernia after ileal conduit using prophylactic mesh: A meta-analysis of randomized controlled trials\u003Cbr>Hamza Elhashamy a, Tarek Mohamedb, Baha’ Aldeen Bani Irshidc, Mohammad Ghassab Deamehd and Mohamed Rameze\u003Cbr>a Faculty of Medicine, Assiut University, Assiut, Egypt; bUrology department, United Lincolnshire Hospitals NHS Trust, Lincoln, UK; cPrincess Basma Teaching Hospital, Irbid, Jordan; dPrince Hamza Hospital, Amman, Jordan; e Urology Department, University of Texas MD Anderson Cancer Center, Houston, TX, USA |  |  |\n| --- | --- | --- |\n| ABSTRACT\u003Cbr>Purpose: This study aims at assessing the effectiveness of using prophylactic mesh for the prevention of Parastomal hernia (PSH) after cystectomy and ileal conduit.\u003Cbr>Methods: PRISMA statement guidelines were followed. A comprehensive literature search was conducted across PubMed, MEDLINE, Cochrane Library, and Embase databases. The primary outcomes analyzed were operation time, clinical hernia, radiological hernia, and complications classified as greater than or less than 3 on the Clavien-Dindo scale.\u003Cbr>Results: Three RCTs with a total number of 782 patients were included. The occurrence of clinical hernia significantly favored the mesh group, with a risk ratio (RR) of 0.50 (p \u003C 0.002) . However, the occurrence of radiological hernia showed no significant difference between groups, with an RR of 0.72 (p = 0.10) . The analysis of operation time significantly favored the no mesh group, with a mean difference (MD) of −28.56 minutes (p \u003C 0.002), indicating shorter operation times compared to the mesh group. Regarding complications, no significant differences were observed between the mesh and no mesh groups. For Clavien–Dindo Grade ≥3 complications, the RR was 1.11 (p = 0.42), and for Clavien–Dindo Grade \u003C3 complications, the RR was 1.15 (p = 0.36)\u003Cbr>Conclusion: Prophylactic mesh significantly reduces the incidence of PSH following ileal conduit. However, it does not significantly affect radiological hernia rates or complication rates. Despite longer operation times, its use offers a clear benefit in preventing PSH without substantially increasing complications. |  | ARTICLE HISTORY\u003Cbr>Received 20 February 2025 Accepted 25 June 2025\u003Cbr>KEYWORDS\u003Cbr>Prophylactic mesh; ileal conduit; parastomal hernia |\n| Introduction | The management of PSH is complex, with high rates |  |\n| Parastomal hernia (PSH) is a frequent complication that | of recurrence and complications [6] . Different surgical |  |\n| occurs after ileal conduit urinary diversion [1] . The | techniques have limitations, such as suture repair and |  |\n| incidence of PSH formation ranges from 4.1% to | stoma relocation. Suture repair’s high recurrence rates |  |\n| 27.6% based on clinical examination alone and from | contribute to its decline in use, and stoma relocation is |  |\n| 13. 9% to 35.4% based on clinical examination and | complicated by anatomical constraints and higher |  |\n| computed tomography (CT) scan combined [2] . | recurrence rates [7] . Hence, there have been a lot of |  |\n| Several factors contribute to the formation of PSH, | efforts to look at the prevention of PSH. |  |\n| including high body mass index (BMI), previous abdom- | The effectiveness of mesh repair for other types of |  |\n| inal surgeries, low pre-operative albumin levels, chronic | incisional hernias has naturally sparked interest in |  |\n| cough and history of radiation therapy [3] . This can | using it for PSH [8] . Prophylactic mesh placement dur- |  |\n| affect the appearance of the abdominal wall, resulting | ing the initial surgery is a strategy considered to |  |\n| in discomfort, bloating, and intermittent pain around | decrease the rate of PSH formation. Studies have |  |\n| the stoma. It can also cause problems with stoma bag | shown that using prophyla","cbCaihEW4ZKjMGEs","https://ap.wps.com/l/cbCaihEW4ZKjMGEs","pdf",5002666,"English","# Abstract\n# Introduction\n# Methods\n## Literature search strategy\n# Results\n# Conclusion","[{\"question\":\"What was the purpose of this study?\",\"answer\":\"To assess the effectiveness of prophylactic mesh in preventing parastomal hernia after cystectomy and ileal conduit.\"},{\"question\":\"How were the outcomes evaluated in the meta-analysis?\",\"answer\":\"Outcomes included operation time, clinical hernia, radiological hernia, and complications categorized by Clavien-Dindo grade.\"},{\"question\":\"Does prophylactic mesh reduce complications or only clinical PSH?\",\"answer\":\"Mesh significantly reduces clinical PSH incidence, but it does not significantly affect radiological hernia rates or overall complication rates.\"}]","Prevention of parastomal hernia after ileal conduit using prophylactic mesh - A meta-analysis of randomized controlled trials | PDF",1790729977]