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This systematic review and meta-analysis assessed the prevalence and risk factors of sleep disturbances in lung cancer patients by screening seven electronic databases. Thirty-seven eligible studies were included, with pooled prevalence reported and subgroup analyses performed to explore heterogeneity across studies.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/prevalence-and-risk-factors-of-sleep-disturbances-among-patients-with-lung-cancer-systematic-review-and-meta-analysis/332407/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/prevalence-and-risk-factors-of-sleep-disturbances-among-patients-with-lung-cancer-systematic-review-and-meta-analysis/332407.png","ImageObject",300,407,{"name":92,"@type":93},"Asher","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-28","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the purpose of this systematic review and meta-analysis?","Question",{"text":112,"@type":113},"To determine the prevalence and risk factors of sleep disturbances in patients with lung cancer, supporting efforts to reduce symptom burden and improve quality of life.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the evidence collected for this review?",{"text":117,"@type":113},"Seven electronic databases were systematically screened for studies reporting the prevalence or risk factors of sleep disturbances in lung cancer patients, with subgroup analyses used to investigate heterogeneity.",{"name":119,"@type":110,"acceptedAnswer":120},"What did the study find about prevalence and key risk factors?",{"text":121,"@type":113},"Sleep disturbances were experienced in more than 60% of lung cancer patients. 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Understanding the prevalence and risk factors of sleep disturbances in lung cancer populations is critical in reducing symptom burden and improving their quality of life. This systematic review aimed to determine the prevalence and risk factors of sleep disturbances in patients with lung cancer. Methods Seven electronic databases were systematically screened for studies on the prevalence or risk factors of sleep disturbances in patients with lung cancer. Subgroup analyses were conducted to investigate significant heterogeneity (I2 > 50%) across studies.  \nResults Thirty-seven studies were found eligible. The pooled prevalence was 0.61 (95% CI = [0 .54–0. 67], I2 = 96%, p \u003C 0.00001) . Seven risk factors were subject to meta-analyses. Significant differences were found for old age (OR = 1.23; 95% CI = [1 .09–1.39], p = 0.0006,I2 = 39%), a low education level (OR = 1. 17; 95%CI = [1 .20–2.66], p = 0.004, I 2 = 42%), fatigue (OR = 1.98; 95%CI = [1 .23–3. 18], p = 0.005, I 2 = 31%), pain (OR = 2.63; 95% CI = [1 .35–5. 14], p = 0.005, I 2 = 91%), tumor stage of III or IV (OR = 2.05; 95%CI = [1 .54–2.72], p \u003C 0 .00001, I 2 = 42%), anxiety (OR = 1.62; 95%CI = [1 .22–2. 14], p = 0.0008, I2 = 78%), and depression (OR = 4.02; 95% CI = [1 .39–11.61], p = 0.01, I2 = 87%) . After the included studies were withdrawn one after the other, pain (OR = 3. 13; 95% CI = [2 .06–4.75], p \u003C 0 .00001, I 2 = 34%) and depression (OR = 5.47; 95% CI = [2.65–11.30], p \u003C 0.00001) showed a substantial decrease of heterogeneity. Meanwhile, the heterogeneity of anxiety symptoms remained unchanged.  \nConclusion Results showed that sleep disturbances were experienced in more than 60% of patients with lung cancer. The comparatively high prevalence of sleep disturbances in this population emphasizes the need to adopt measures to reduce them. Significant associations were found between sleep disturbances and various factors, including age, education level, fatigue, pain, cancer stage, anxiety, and depression. Among these factors, depression emerged as the most significant. Future research should concentrate on identifying high-risk individuals and tailored interdisciplinary interventions based on these risk factors.  \nKeywords Systematic review · Meta-analysis · Sleep disturbances · Prevalence · Risk factors · Lung cancer  \n* Yao Wang [yaowang0428@163.com](yaowang0428@163.com)[ ](yaowang0428@163.com)Ying Hu [huying202102@163.com](huying202102@163.com)[ ](huying202102@163.com)Lily Dongxia Xiao [lily.xiao@flinders.edu.au](lily.xiao@flinders.edu.au)[ ](lily.xiao@flinders.edu.au)Caiyun Tang [tangcaiyun1997@163.com](tangcaiyun1997@163.com)[ ](tangcaiyun1997@163.com)Wenhui Cao [caowenhui@hnca.org.cn](caowenhui@hnca.org.cn)  \n1 Xiangya Nursing School, Central South University, Changsha, Hunan, China  \n2 College of Nursing and Health Sciences, Flinders University, Adelaide, South Australia, Australia  \n3 The Second Department of Thoracic Internal Medicine, Hunan Cancer Hospital, Changsha, Hunan, China  \nIntroduction  \nLung cancer is one of the most common malignancies. Lung cancer has the highest mortality rate (18.0%) and the second highest incidence (11.4%) among all cancers worldwide, as stated in the Global Cancer Statistics 2020 [1] . In recent years, the promotion and application of lung cancer treatments have improved the survival rate of patients with lung cancer [2] . However, this situation also means that the various symptoms accompanying the disease and trea","cbCaifRqnVol0sOr","https://ap.wps.com/l/cbCaifRqnVol0sOr","pdf",1833329,25,"English","# Abstract\n## Purpose\n## Methods\n## Results\n## Conclusion\n# Introduction","[{\"question\":\"What is the purpose of this systematic review and meta-analysis?\",\"answer\":\"To determine the prevalence and risk factors of sleep disturbances in patients with lung cancer, supporting efforts to reduce symptom burden and improve quality of life.\"},{\"question\":\"How was the evidence collected for this review?\",\"answer\":\"Seven electronic databases were systematically screened for studies reporting the prevalence or risk factors of sleep disturbances in lung cancer patients, with subgroup analyses used to investigate heterogeneity.\"},{\"question\":\"What did the study find about prevalence and key risk factors?\",\"answer\":\"Sleep disturbances were experienced in more than 60% of lung cancer patients. Risk factors associated with sleep disturbances included age, education level, fatigue, pain, cancer stage, anxiety, and depression, with depression identified as the most significant.\"}]","Prevalence and risk factors of sleep disturbances among patients with lung cancer - systematic review and meta-analysis | PDF",1789998089,63]