[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-402282-105":59,"doc-detail-402282-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","prep-research-prep-research-care-navigation-guide","PrEP Research - PrEP research care navigation guide","","Pre-exPosure ProPhylaxis (PrEP) is presented through a frontline provider manual focused on PrEP research, care, and navigation. The material explains what PrEP is and how prophylaxis works to prevent HIV before, during, and after sexual exposure or needle sharing. It summarizes key study evidence supporting preventive interventions and discusses how PrEP functions in the body, including the potential for resistance and breakthrough infections. It also outlines practical workflows for screening, visits, adherence, side effects, and access pathways for clients.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/prep-research-prep-research-care-navigation-guide/402282/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/prep-research-prep-research-care-navigation-guide/402282.png","ImageObject",300,407,{"name":92,"@type":93},"PakDamar76","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-27",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What does “prophylaxis” mean in the context of PrEP?","Question",{"text":112,"@type":113},"Prophylaxis means taking a drug or drugs before exposure to something that could cause an infection. For PrEP, an HIV-negative person can take it daily to help prevent HIV infection from exposure during and after sex or needle sharing.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How does PrEP prevent HIV according to the manual’s explanation of the HIV life cycle?",{"text":117,"@type":113},"The manual describes HIV’s steps: attaching to immune cells, entering the cell, converting genetic material from RNA to DNA, merging into the cell’s DNA, and then producing more HIV until it becomes a chronic infection. This provides the biological basis for prevention through PrEP.",{"name":119,"@type":110,"acceptedAnswer":120},"How is the manual organized for providers?",{"text":121,"@type":113},"The manual is divided into three sections: PrEP research, PrEP care, and PrEP navigation. Each section contains separate information sheets on individual topics, so navigators can print the full manual or only the needed sections.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},402282,1791094045,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},962090893057,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Helping people access Pre-exPosure  \nProPhylaxis  \nA frontline provider manual on PrEP research, care and navigation  \nFeBruary 2018  \n[projectinform.org/prep-manual](projectinform.org/prep-manual)[ ](projectinform.org/prep-manual)[pleaseprepme.org/](pleaseprepme.org/)[ ](pleaseprepme.org/)prepnavigatormanual  \nwelcome!   \nAlan, Shannon, Charlie, Laura, Reilly  \n[pleaseprepMe.org](pleaseprepMe.org) is excited to provide this resource.  \nWe want to provide a well-rounded set of materials to help you help your clients and patients understand the range of information that’s available on PrEP. We hope you find it useful in your work.  \nThis manual is a living document, so we’ll continue to update it and add new sections on topics of interest from the field. It’s divided into three sections: PrEP research, PrEP care and PrEP navigation. Within each section, there are separate info sheets on individual topics.  \nWe’ve designed it this way so navigators can print the entire manual or just those sections they want to have handy. The pages can be easily put into a ring binder. Feel free to print what you need and share the manual in print or PDF.  \nThe latest version of the PDF will always be available at project [inform.org/prep-manual](inform.org/prep-manual. There)[. There](inform.org/prep-manual. There)’s also an online form there to enter your contact info so we can let you know of updates.  \nplease email Contact@PleasePrEPMe.org with any questions or suggestions on how to improve this resource.  \n  [P r o j e c t i n F o r m . o r g / P r e P - m a n u a l](P r o j e c t i n F o r m . o r g / P r e P - m a n u a l)  \ncontents  \n1  PrEP RESEARCH  \nThe HIV prevention toolbox What is PrEP?  \nHow does PrEP work? What types of PrEP are there? Studies to date  \nGeneral observations from studies FDA approval of Truvada for PrEP What isTruvada for PrEP?  \nTreatment as Prevention  \nPrEP and resistant HIV Breakthrough HIV infections Resources for PrEP research  \n2  PrEP CARE  \nThe PrEP care continuum Who are, aren’t candidates for PrEP? Screening for PrEP  \nSymptoms of acute HIV infection Before first medical visit  \nFirst medical visit  \nOngoing medical visits  \nSchedule of routine screenings PrEP-related ICD, CPT and LOINC codes Prior authorizations and denials When to start and stop  \nSide effects  \nAdherence: factors and strategies Missed doses and refills Hepatitis B and C and PrEP  \nPrEP and safer conception options Disclosure, stigma and concealment PrEP and hormones (coming soon) Post-Exposure Prophylaxis (PEP) Resources for PrEP care  \n3  PrEP NAVIGATION  \nNavigator role, responsibilities Federal Poverty Level  \nHealth care terms  \nAssessing client insurance status Finding insurance, health care Covered California plans  \nFinding a PrEP provider  \nCovering costs of PrEP care  \nCalifornia PrEP AP  \nAdvancing Access Program Patient Access Network Foundation Patient Advocate Foundation  \nPharmacy issues  \nFlexible spending accounts  \nKaiser MFA Program  \nUndocumented individuals (coming soon) Minors and PrEP (coming soon)  \nYouth and PrEP (coming soon) Nurx and PlushCare  \nPrEP and life insurance (coming soon) Case studies  \nResources for PrEP navigation  \n ACKNOWLEDGEMENTS  \n[P r o j e c t i n F o r m . o r g / P r e P - m a n u a l](P r o j e c t i n F o r m . o r g / P r e P - m a n u a l)    \nPrEP Research  \n1  \nThis section provides the clinical study data that laid the groundwork for approving Truvada for PrEP as a new biomedical method for preventing HIV infection. It also describes how PrEP works within the body, the possibility of resistance and the few cases of breakthrough HIV infections known to date.  \nThe HIV prevention toolbox  \nprep is one of many tools that a person can use to reduce their risk for hiv infection.  \nA great deal of clinical data support most of these preventive interventions in the toolbox on the right, and some offer higher rates of protection than others.  \nWhen a person uses more than one method—as","cbCaigE1VmFTZGU9","https://ap.wps.com/l/cbCaigE1VmFTZGU9","pdf",4801778,68,"English","# PrEP research\n## The HIV prevention toolbox\n## What is PrEP?\n## How does PrEP work?\n## What types of PrEP are there?\n## Studies to date\n## FDA approval of Truvada for PrEP\n## Treatment as Prevention\n## PrEP and resistant HIV\n## Breakthrough HIV infections\n## Resources for PrEP research\n# PrEP care\n## The PrEP care continuum\n## Who are, aren’t candidates for PrEP?\n## Screening for PrEP\n## Symptoms of acute HIV infection\n## Before first medical visit\n## First medical visit\n## Ongoing medical visits\n## Schedule of routine screenings\n## Side effects\n## Adherence: factors and strategies\n## Missed doses and refills\n## Hepatitis B and C and PrEP\n## PrEP and safer conception options\n## Disclosure, stigma and concealment\n## Post-Exposure Prophylaxis (PEP)\n## Resources for PrEP care\n# PrEP navigation\n## Navigator role, responsibilities\n## Assessing client insurance status\n## Finding a PrEP provider\n## Covering costs of PrEP care\n## Case studies\n## Resources for PrEP navigation","[{\"question\":\"What does “prophylaxis” mean in the context of PrEP?\",\"answer\":\"Prophylaxis means taking a drug or drugs before exposure to something that could cause an infection. For PrEP, an HIV-negative person can take it daily to help prevent HIV infection from exposure during and after sex or needle sharing.\"},{\"question\":\"How does PrEP prevent HIV according to the manual’s explanation of the HIV life cycle?\",\"answer\":\"The manual describes HIV’s steps: attaching to immune cells, entering the cell, converting genetic material from RNA to DNA, merging into the cell’s DNA, and then producing more HIV until it becomes a chronic infection. This provides the biological basis for prevention through PrEP.\"},{\"question\":\"How is the manual organized for providers?\",\"answer\":\"The manual is divided into three sections: PrEP research, PrEP care, and PrEP navigation. Each section contains separate information sheets on individual topics, so navigators can print the full manual or only the needed sections.\"}]","PrEP Research - PrEP research care navigation guide | PDF",1790528735,171]