[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-401300-105":59,"doc-detail-401300-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","prep-on-demand-dosing-schedule-and-instructions","PrEP “On Demand” - Dosing Schedule and Instructions","","PrEP “On Demand” guidance outlines a 2-1-1 dosing schedule tied to timing of anal sex. It explains when to take two tablets before sex and then 1 tablet at 24 hours and 48 hours after the first dose, with an extra 72-hour dose if sex occurs 24 hours later than planned. It also covers adjustments for multiple sex occasions, switching to daily PrEP if sex is more than twice per week, and maintaining HIV testing every 3 months.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/prep-on-demand-dosing-schedule-and-instructions/401300/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/prep-on-demand-dosing-schedule-and-instructions/401300.png","ImageObject",300,407,{"name":92,"@type":93},"Dipper","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-27",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",13,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Who is PrEP “On Demand” approved for?","Question",{"text":113,"@type":114},"PrEP “on demand” is only approved for people who have anal sex.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What is the 2-1-1 dosing schedule for PrEP “On Demand”?",{"text":118,"@type":114},"Take two tablets 2–24 hours (ideally 24 hours) before sex, then take 1 tablet 24 hours after the first dose and 1 tablet 48 hours after the first dose.",{"name":120,"@type":111,"acceptedAnswer":121},"When should someone switch to daily PrEP and how often is HIV testing needed?",{"text":122,"@type":114},"If having sex more than twice a week, take daily PrEP instead. HIV testing is still needed every 3 months.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},401300,1790587724,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":105,"preview_page_count":4},1374404997633,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","PrEP “On  \nDemand”  \nExample: Fri 10 am  \n(Fri 10 pm)  \nSat  \n10 am  \nSun  \n10 am  \n-24 hours -2 hours 0 hour  \nFirst dose  \n24 hours after first dose  \nSecond dose  \n48 hours after first dose  \nThird dose  \nWhat if he cancels but we reschedule for the next day?  \nTake another pill.  \nExample: Fri 10 am  \n(Fri night)  \nSat 10 am  \n(Sat night)  \nSun 10 am Mon 10 am  \n-24 hours -2 hours   \nFirst dose  \n24 hours after first dose  \n48 hours after first dose  \n72 hours after first dose  \nSecond dose Sex Third dose Fourth dose  \nWhat if it goes so well he comes back the next day (or  \nsomeone else)? Take another pill.  \nExample: Fri 10 am Sat 10 am  \n(Fri night) (Sat night)  \nSun 10 am Mon 10 am  \n-24 hours -2 hours  \n24 hours after first dose  \n48 hours after first dose  \n72 hours after first dose  \nFirst dose Sex Second dose Sex Third dose Fourth dose  \nWhat if he (or someone else) keeps coming back for more?  \nTake daily PrEP.  \nExample: Fri 10 am Sat 10 am Sun 10 am Mon 10 am Tue 10 am  \n(Fri night) (Sat night) (Sun night)  \n-24 hours -2 hours  \nSex  \n24 hours after first dose  \nSecond dose  \nSex  \n48 hours after first dose  \nThird dose  \n72 hours after first dose  \n96 hours after first dose  \nFourth dose  \nFifth dose  \nHow to take PrEP “On Demand”  \nHere is how you can follow the 2-1-1 dosing schedule of PrEP.  \n• PrEP “on demand’ is only approved for people who have anal sex.  \n• As a first dose, take two tablets 2-24 hours (ideally 24 hours) before sex.  \n• As a second dose, take 1 tablet 24 hours after the first dose.  \n• As a third dose, take 1 tablet 48 hours after the first dose.  \n• If you have sex 24 hours later than planned, take an additional tablet 72 hours after the first dose.  \n• If you have sex multiple times, keep on taking additional tablets until you have taken two tablets in the 48 hours (once every 24 hours) after your last sexual encounter.  \n• If you have sex more than twice a week, take daily PrEP instead.  \n• You still need HIV testing every 3 months.","cbCaisxhzO5K8UUT","https://ap.wps.com/l/cbCaisxhzO5K8UUT","pdf",494469,"English","# PrEP “On Demand” overview\n## 2-1-1 schedule examples\n## Taking doses based on timing\n## When to switch to daily PrEP\n## HIV testing requirement","[{\"question\":\"Who is PrEP “On Demand” approved for?\",\"answer\":\"PrEP “on demand” is only approved for people who have anal sex.\"},{\"question\":\"What is the 2-1-1 dosing schedule for PrEP “On Demand”?\",\"answer\":\"Take two tablets 2–24 hours (ideally 24 hours) before sex, then take 1 tablet 24 hours after the first dose and 1 tablet 48 hours after the first dose.\"},{\"question\":\"When should someone switch to daily PrEP and how often is HIV testing needed?\",\"answer\":\"If having sex more than twice a week, take daily PrEP instead. HIV testing is still needed every 3 months.\"}]","PrEP “On Demand” - Dosing Schedule and Instructions | PDF",1790518544]