[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-400658-105":59,"doc-detail-400658-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","prep-on-demand-a-users-guide-prep-on-demand-actioncompleteness-phrase","PrEP on Demand: A User’s Guide - PrEP on Demand Action/Completeness Phrase","","PrEP on Demand is a safe, effective HIV prevention option using pre-exposure prophylaxis as either a daily pill or an injection every two months. Men who have sex with men may take PrEP pills only before and after sex, following the 2-1-1 dosing schedule. The guide explains effectiveness for anal sex, limits for receptive vaginal sex, and the need to take every dose. It also covers dosing steps, reminders, missed-dose guidance, and side-effect management, with direction to consult providers and emergency PEP if needed.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/prep-on-demand-a-users-guide-prep-on-demand-actioncompleteness-phrase/400658/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/prep-on-demand-a-users-guide-prep-on-demand-actioncompleteness-phrase/400658.png","ImageObject",300,407,{"name":92,"@type":93},"SANS","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-27",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is PrEP on Demand and how is it taken?","Question",{"text":112,"@type":113},"PrEP (pre-exposure prophylaxis) is medicine that prevents HIV. PrEP on demand involves taking PrEP pills only before and after sex for men who have sex with men.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What is the 2-1-1 dosing schedule for PrEP on demand?",{"text":117,"@type":113},"If having sex once, take 2 pills 2 to 24 hours before sex, then take 1 pill 24 hours after the first dose and 1 pill 48 hours after the first dose.",{"name":119,"@type":110,"acceptedAnswer":120},"Does PrEP on demand prevent HIV for receptive vaginal sex and what should people do instead?",{"text":121,"@type":113},"PrEP on demand may not prevent HIV during receptive vaginal sex and has only been studied using Truvada and its generic. People who have receptive vaginal sex should take a daily PrEP pill or injectable PrEP.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},400658,1791099743,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":14,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":24,"preview_page_count":4},962090760505,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","PrEP on Demand: A User’s Guide  \nPrEP To Prevent HIV  \nPrEP (pre-exposure prophylaxis) is safe and effective medicine that prevents HIV It is available as a daily pill or an injection you receive every two months.  \nTaking PrEP on Demand  \nMen who have sex with men can use PrEP “on demand,” taking PrEP pills only before and after sex. PrEP on demand may be a good option for men who have sex with men and who:  \n• Have sex occasionally  \n• Can anticipate when they will have sex  \nTaking PrEP on demand has only been studied and recommended for men who have sex with men. PrEP on demand is very effective at preventing HIV during anal sex. It may not prevent HIV during receptive vaginal sex and has only been studied using Truvada and its generic.  \n2-1-1 Schedule  \nIf you have sex one time, take:  \n• 2 pills 2 to 24 hours before sex (the first dose)  \n• 1 pill 24 hours after the first dose  \n• 1 pill 48 hours after the first dose  \n10 p. m.  \nSex  \nWednesday Thursday Friday Saturday Sunday Monday Tuesday  \nBefore Sex  \nTake a first dose of two PrEP pills at least two hours before sex (closer to 24 hours before sex is ideal) .  \nNoon Noon Noon  \nAfter Sex  \nTake one PrEP pill 24 hours after the first dose.  \nTake another PrEP pill 48 hours after the first dose.  \nIf you continue to have sex more than 24 hours after your first dose, continue taking one pill every 24 hours until you have taken two pills after you last had sex. Take every dose as scheduled.  \nAdapted from HIV i-Base’s 2:1:1 dosing guide: [i-base.info/guides/prep/real-life-examples-for-on-demand-dosing](i-base.info/guides/prep/real-life-examples-for-on-demand-dosing).  \nTake Every Dose as Scheduled  \n• If it has been less than two hours since your first dose of PrEP on demand, use condoms or wait to have sex.  \n• Make sure to take daily doses for two days after you last have sex.  \n• Set reminders on your phone or in your calendar to take each dose.  \n• If you miss a dose, emergency PEP (post-exposure prophylaxis) can prevent HIV after exposure. Contact your health care provider or the 24/7 NYC PEP Hotline at 844-3-PEPNYC (844-373-7692) .  \nPrEP on demand is very effective at preventing HIV if you take every dose and use it every time you have sex.  \nKnow if PrEP on Demand Is Right for You  \nPrEP medicines take longer to get into vaginal tissue or blood than anal tissue. People who have receptive vaginal sex or inject drugs should take a daily PrEP pill or injectable PrEP.  \nMen who have sex with men can safely switch between taking daily PrEP and PrEP on demand. Talk to your provider about which may be right for you.  \nAddress Any Side Effects  \nPrEP medicines may cause mild side effects, including nausea, upset stomach, fatigue, and headaches. These side effects often get better or go away during the first month of taking PrEP Talk to your provider if side effects continue to bother you.  \n• To prevent nausea, take PrEP with a snack. To make nausea less noticeable, take PrEP before bed. To relieve nausea, try ginger candy or peppermint tea.  \n• To reduce gas or bloating, try an over-the-counter gas reliever.  \n• If soft stools bother you, try a fiber supplement.  \nFor more information and additional user’s guides, [visit](visit nyc.gov/health/hiv or)[ nyc.gov/health/hiv](visit nyc.gov/health/hiv or)[ or](visit nyc.gov/health/hiv or) scan the QR code.  \n11.24","cbCainrZjr0EUqOK","https://ap.wps.com/l/cbCainrZjr0EUqOK","pdf",91881,"English","# Taking PrEP on Demand\n## Who PrEP on Demand is for\n## Effectiveness and study limits\n## 2-1-1 schedule\n## If you continue having sex\n## Take every dose as scheduled\n# When PrEP on Demand is right for you\n## Switching to daily PrEP\n# Side effects and how to manage them\n# Get more information","[{\"question\":\"What is PrEP on Demand and how is it taken?\",\"answer\":\"PrEP (pre-exposure prophylaxis) is medicine that prevents HIV. PrEP on demand involves taking PrEP pills only before and after sex for men who have sex with men.\"},{\"question\":\"What is the 2-1-1 dosing schedule for PrEP on demand?\",\"answer\":\"If having sex once, take 2 pills 2 to 24 hours before sex, then take 1 pill 24 hours after the first dose and 1 pill 48 hours after the first dose.\"},{\"question\":\"Does PrEP on demand prevent HIV for receptive vaginal sex and what should people do instead?\",\"answer\":\"PrEP on demand may not prevent HIV during receptive vaginal sex and has only been studied using Truvada and its generic. People who have receptive vaginal sex should take a daily PrEP pill or injectable PrEP.\"}]","PrEP on Demand: A User’s Guide - PrEP on Demand Action/Completeness Phrase | PDF",1790513014]