[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-400660-105":59,"doc-detail-400660-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","prep-dosing-guide-dosage-regimens-daily-prep-and-on-demand-prep","PrEP Dosing Guide - Dosage Regimens - Daily PrEP and On-demand PrEP","","PrEP dosing guide detailing two oral regimens using co-formulated tenofovir and emtricitabine (TD*/FTC) to reduce HIV transmission risk. Daily PrEP instructions cover starting before potential exposure, taking one tablet each day for protection, required 3-monthly monitoring, and stopping guidance after the last exposure. On-demand PrEP instructions describe timing for initiating 2–24 hours before sex, tablet sequencing after intercourse, handling repeat sex within defined windows, screening, and key populations for whom on-demand PrEP is not recommended due to efficacy limits and hepatitis B risks.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/prep-dosing-guide-dosage-regimens-daily-prep-and-on-demand-prep/400660/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/prep-dosing-guide-dosage-regimens-daily-prep-and-on-demand-prep/400660.png","ImageObject",300,407,{"name":92,"@type":93},"Indoniesian Boy","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-27",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"How is daily PrEP started and taken before potential HIV exposure?","Question",{"text":113,"@type":114},"Take TD*/FTC daily for 7 days before potential HIV exposure. For MSM whose risk is from anal intercourse, PrEP can be started by taking two tablets 2–24 hours before intercourse, then continuing with daily dosing.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What monitoring schedule is recommended while on daily PrEP?",{"text":118,"@type":114},"Screening/monitoring should occur every three months, as noted in the Australian PrEP guidelines, with details available in the “Decision Making in PrEP” tool.",{"name":120,"@type":111,"acceptedAnswer":121},"How does on-demand PrEP dosing work around a single sexual exposure?",{"text":122,"@type":114},"If risk is anticipated, take two tablets 2–24 hours before intercourse. After intercourse, take a single tablet 24 hours after the first two tablets, then the fourth tablet 24 hours after the third tablet, adjusting to additional sex within the 48-hour window.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},400660,1790694150,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":14,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":24,"preview_page_count":4},962090760608,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","PrEP DOSING GUIDE  \nPrEP DOSING REGIMENS Daily PrEP  \nProviding daily PrEP  \n• Initial script to be provided to patient for daily, continuing, oral dose of co-formulated tenofovir and emtricitabine (TD*/FTC) . PBS streamlined authority: 7580.  \nHow to take daily PrEP  \n• 7 days of daily TD*/FTC prior to potential HIV exposure, to ensure adequate protection.  \n• Exception: MSM whose risk of HIV is from anal intercourse can start PrEP by taking two tablets 2-24 hours before intercourse, followed by daily dosing.  \n• Take one tablet every day.  \nMonitoring while on Daily PrEP  \n• Every three months as noted in the Autralian PrEP guidelines. See the “Decision Making in  PrEP” tool for details.  \nCessation of Daily PrEP  \n• Australian PrEP guidelines recommend continuation of daily PrEP for 7 days after last potential exposure to HIV.  \n• MSM whose risk of HIV is from anal intercourse can stop PrEP by taking two tablets after the last intercourse. Take one tablet 24 hours and one tablet 48 hours after the last intercourse.  \n• People with Hepatitis B (HBsAg+) are at risk of acute hepatitis after cessation of PrEP. Cessation of PrEP should be done in consultation with a specialist.  \nFor more information, please refer to the “Decision Making in PrEP” tool  \n = PrEP  = HIV risk exposure  \nPrEP DOSING REGIMENSOn-demand PrEP  \nOn-demand PrEP can be used daily for short periods of time, or around single events of HIV exposure.  \nWho is on-demand PrEP suitable for?  \n• As on-demand PrEP needs to be started at least 2 hours before sex, users of on-demand PrEP do need to be able to predict sexual activity or delay sexual activity by two hours. If spontaneous sexual activity is more likely, this person may be more suited to a daily PrEP regimen that involves taking TD*/FTCon a daily basis during periods of risk.  \n• On-demand PrEP may also be suitable for MSM who have had side effects from daily PrEP such as nausea, diarrhoea or changes in renal function.  \n• On-demand PrEP is not recommended for females, heterosexuals, and trans and gender diverse people, and people who inject drugs,  \ndue to lack of efficacy data in these populations.  \n• Due to risk of reactivation of hepatitis B infection and risk of HBV resistance mutations, on-demand PrEP is not recommended for people living with chronic hepatitis B infection (HBsAg+) .  \nProviding on-demand PrEP  \n• 90 tablet supply (which is not usually 90 days for on-demand PrEP) of TD*/FTC supplied as per PBS / Australian PrEP guidelines. PBS streamlined authority: 7580  \nHow to take on-demand PrEP  \n• If a person believes they may have an episode of risk, they take two tablets of PrEP (TD*/FTC) 2 to 24 hours before intercourse.  \n• If intercourse has occurred the person takes a single tablet of TD*/FTC 24 hours after the first two tablets, and the fourth tablet  \n24 hours after the third tablet.  \n• If sexual intercourse occurs again during the 48 hours after the initial dose, then only one tablet with once-daily PrEP dosing until 48 hours after the last act of sex is reached.  \n• If sexual activity is resumed within one week of the last tablet of PrEP, then only one tablet loading dose of TD*/FTC is required. If sexual intercourse is resumed more than 7 days after the last PrEP tablet, then the two-tablet loading dose is required as noted above.  \nPrEP on-demand screening  \n• As with all PrEP regimens 3-monthly screening is vital, see the “Decision Making in PrEP” tool for more information.  \nStart 2-24 hours before  \nExample of on-demand PrEP when there are more than 7 days between the next exposure and the last tablet  \n\n| SUNDAY | MONDAY | TUESDAY | WEDNESDAY | THURSDAY | FRIDAY | SATURDAY |\n| --- | --- | --- | --- | --- | --- | --- |\n|  | 1 | 2 | 3 | 4 | 5\u003Cbr>19:00-24 hours before\u003Cbr>| 6\u003Cbr>19:00\u003Cbr>|\n| 7\u003Cbr>19:00\u003Cbr>| 8\u003Cbr>19:00\u003Cbr>| 9 | 10 | 11 | 12 | 13 |\n| 14 | 15 | 16 | 17 | 18\u003Cbr>20:00-2 hours before\u003Cbr>| 19\u003Cbr>20:00\u003Cbr>| 20\u003Cbr>20:00\u003Cbr>|\n| 21 | 22 | 23 | 24 | 25 | 26 | 27 |\n| 28 | 29\u003C","cbCaiv8NuIEfqYtx","https://ap.wps.com/l/cbCaiv8NuIEfqYtx","pdf",176218,"English","# PrEP Dosing Regimens\n## Daily PrEP\n## Monitoring while on Daily PrEP\n## Cessation of Daily PrEP\n## On-demand PrEP\n## Who is on-demand PrEP suitable for?\n## Providing on-demand PrEP\n## How to take on-demand PrEP\n## PrEP on-demand screening","[{\"question\":\"How is daily PrEP started and taken before potential HIV exposure?\",\"answer\":\"Take TD*/FTC daily for 7 days before potential HIV exposure. For MSM whose risk is from anal intercourse, PrEP can be started by taking two tablets 2–24 hours before intercourse, then continuing with daily dosing.\"},{\"question\":\"What monitoring schedule is recommended while on daily PrEP?\",\"answer\":\"Screening/monitoring should occur every three months, as noted in the Australian PrEP guidelines, with details available in the “Decision Making in PrEP” tool.\"},{\"question\":\"How does on-demand PrEP dosing work around a single sexual exposure?\",\"answer\":\"If risk is anticipated, take two tablets 2–24 hours before intercourse. After intercourse, take a single tablet 24 hours after the first two tablets, then the fourth tablet 24 hours after the third tablet, adjusting to additional sex within the 48-hour window.\"}]","PrEP Dosing Guide - Dosage Regimens - Daily PrEP and On-demand PrEP | PDF",1790513018]