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The case describes a 39-year-old Gravida 3 Para 2 woman with achondroplasia and two prior caesarean sections who received consultant-led multidisciplinary antenatal care across obstetrics, anaesthesiology, cardiology, and neonatology teams. An elective lower segment caesarean section with bilateral tubal ligation at 37 weeks under combined spinal-epidural anesthesia resulted in an uncomplicated maternal and neonatal recovery. Neonatal assessment showed no clinical, radiological, or genetic evidence of achondroplasia, highlighting the role of individualized planning, early anaesthetic assessment, detailed anomaly scanning, prenatal counseling, and risk evaluation to minimize complications. Postoperative maternal monitoring included hypertensive episode vigilance and adjusted obstetric hemorrhage thresholds.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/pregnancy-and-delivery-in-a-woman-with-achondroplasia-a-multidisciplinary-management-approach/455225/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/pregnancy-and-delivery-in-a-woman-with-achondroplasia-a-multidisciplinary-management-approach/455225.png","ImageObject",300,407,{"name":92,"@type":93},"A glass of water","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why is pregnancy management challenging in women with achondroplasia?","Question",{"text":113,"@type":114},"Achondroplasia causes disproportionate short stature and is associated with significant obstetric and anaesthetic challenges. The case also notes obstetric, cardiopulmonary, and delivery-planning risks that require careful assessment.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What multidisciplinary teams were involved in the reported pregnancy?",{"text":118,"@type":114},"The patient received consultant-led multidisciplinary antenatal care involving obstetrics, anaesthesiology, cardiology, and neonatology teams.",{"name":120,"@type":111,"acceptedAnswer":121},"What delivery and anaesthesia approach was used, and what were the outcomes?",{"text":122,"@type":114},"She underwent an elective lower segment caesarean section with bilateral tubal ligation at 37 weeks under combined spinal-epidural anesthesia. Postoperative maternal and neonatal recovery was uneventful, and the neonate showed no clinical, radiological, or genetic evidence of achondroplasia.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},455225,1790792320,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":29,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},962090760832,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Review began 11/24/2025  \nReview ended 12/04/2025  \nPublished 12/08/2025  \n© Copyright 2025  \nBaloch et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0. , which permits unrestricted use , distribution , and reproduction in any medium , provided the original author and source are credited.  \nDOI: 10.7759/cureus.98733  \nOpen Access Case Report  \nPregnancy and Delivery in a Woman With Achondroplasia: A Multidisciplinary Management Approach  \nFalak Baloch 1, Liliana Grosu 1  \n1. Department of Obstetrics and Gynaecology, Bedfordshire Hospitals NHS Foundation Trust, Bedford, GBR Corresponding author: Falak Baloch, [drfalakn1@gmail.com](drfalakn1@gmail.com)  \nAbstract  \nAchondroplasia is the most common skeletal dysplasia, characterised by disproportionate short stature and associated with obstetric and anaesthetic challenges, with limited evidence on optimal pregnancy management. We report a 39-year-old Gravida 3 Para 2 woman with achondroplasia and two previous caesarean sections who received consultant-led, multidisciplinary antenatal care involving obstetrics, anesthesiology, cardiology, and neonatology teams. Her pregnancy was complicated by short stature, prior caesarean deliveries, and previous children affected by achondroplasia. She underwent an elective lower segment caesarean section and bilateral tubal ligation at 37 weeks under combined spinal-epidural anesthesia, delivering a live female infant weighing 2,760 grams (94 .6th centile) with Apgar scores of 9 and 10. Postoperative maternal and neonatal recovery was uneventful, and the neonate showed no clinical, radiological, or genetic evidence of achondroplasia. A tailored multidisciplinary approach, early anesthetic assessment, careful delivery planning, prenatal counseling, and risk evaluation, including discussion of invasive prenatal testing, were crucial to minimize maternal and neonatal complications. Maternal postoperative care included monitoring for hypertensive episodes and adjustment of obstetric hemorrhage thresholds due to body habitus.  \nThis case highlights that pregnancy in women with achondroplasia requires individualized, multidisciplinary care to optimize maternal and neonatal outcomes, with early consultation, detailed anomaly scanning, anesthetic planning, and comprehensive risk assessment being key to successful management.  \nCategories: Obstetrics/Gynecology  \nKeywords: achondroplasia, achondroplastic, combined spinal epidural, dwarfism, pregnancy  \nIntroduction  \nAchondroplasia is the most common form of skeletal dysplasia, characterised by disproportionate short stature due to rhizomelic limb shortening and distinctive craniofacial features [1] . Its prevalence is estimated at 3.72 per 100,000 live births [2] . The condition is caused by a pathogenic variant in the Fibroblast Growth Factor Receptor 3 (FGFR3) gene, which disrupts endochondral ossification during skeletal development [3] . Individuals with achondroplasia may face lifelong complications, including spinal abnormalities, restrictive lung disease, and early childhood mortality [4] .  \nPregnancy in women with achondroplasia is rare and associated with significant obstetric and anaesthetic challenges. Women with this condition are at increased risk of infertility, menorrhagia, dysmenorrhea, leiomyomata, and early menopause [4-6]. Obstetric complications include cephalopelvic disproportion (CPD) necessitating caesarean delivery (CS), preterm birth (PTB), and fetal skeletal dysplasia. At the same time, maternal cardiopulmonary risks are also elevated due to restrictive lung disease and potential cardiac anomalies such as congenital heart diseases, cardiomyopathy, coronary artery disease, and pulmonary hypertension [6-8].  \nDespite concerns about skeletal abnormalities complicating epidural anaesthesia, clinical experience shows no serious complications. While technical issues like dural puncture have occurred, subsequent a","cbCaikbXGC5Md5Eb","https://ap.wps.com/l/cbCaikbXGC5Md5Eb","pdf",127364,"English","# Abstract\n# Introduction\n# How to cite this article\n# Case Presentation","[{\"question\":\"Why is pregnancy management challenging in women with achondroplasia?\",\"answer\":\"Achondroplasia causes disproportionate short stature and is associated with significant obstetric and anaesthetic challenges. The case also notes obstetric, cardiopulmonary, and delivery-planning risks that require careful assessment.\"},{\"question\":\"What multidisciplinary teams were involved in the reported pregnancy?\",\"answer\":\"The patient received consultant-led multidisciplinary antenatal care involving obstetrics, anaesthesiology, cardiology, and neonatology teams.\"},{\"question\":\"What delivery and anaesthesia approach was used, and what were the outcomes?\",\"answer\":\"She underwent an elective lower segment caesarean section with bilateral tubal ligation at 37 weeks under combined spinal-epidural anesthesia. Postoperative maternal and neonatal recovery was uneventful, and the neonate showed no clinical, radiological, or genetic evidence of achondroplasia.\"}]","Pregnancy and Delivery in a Woman With Achondroplasia: A Multidisciplinary Management Approach | PDF",1790742415,15]