[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-433535-105":59,"doc-detail-433535-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","predictors-of-metachronous-advanced-colorectal-adenoma-after-polypectomy","Predictors of metachronous advanced colorectal adenoma after polypectomy","","Adenoma recurrence after polypectomy remains a major clinical concern, requiring improved risk assessment. This retrospective study examined predictors of metachronous advanced colorectal adenomas using metabolic factors and baseline colonoscopic findings, aiming to guide risk stratification and surveillance. Adults undergoing two colonoscopies between January 2014 and February 2020 were analyzed for associations between demographic and metabolic variables and subsequent advanced adenoma development. Multivariate results highlighted age ≥45 years, male sex, and specific baseline colonoscopic patterns.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/predictors-of-metachronous-advanced-colorectal-adenoma-after-polypectomy/433535/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/predictors-of-metachronous-advanced-colorectal-adenoma-after-polypectomy/433535.png","ImageObject",300,407,{"name":92,"@type":93},"Logic","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":24},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the main purpose of this study?","Question",{"text":112,"@type":113},"To identify key risk factors for metachronous advanced colorectal adenomas after polypectomy, focusing on metabolic factors and initial colonoscopic findings to support risk stratification and surveillance recommendations.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the study conducted?",{"text":117,"@type":113},"It was a retrospective hospital-based study of individuals who had two colonoscopies between January 2014 and February 2020, with adenomas detected at the initial examination.",{"name":119,"@type":110,"acceptedAnswer":120},"Which factors were identified as key predictors of metachronous advanced adenomas?",{"text":121,"@type":113},"Multivariate analysis indicated that age ≥45 years, male sex, and baseline colonoscopic findings were major predictors, especially advanced adenomas and multiple adenomas at baseline.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},433535,1790892474,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":24,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":34,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},1099513958762,"https://ap-avatar.wpscdn.com/avatar/1000023916a998db790?x-image-process=image/resize,m_fixed,w_180,h_180&k=1784791008015729253","J Chin MedAssoc  \nOriginal article  \nPredictors of metachronous advanced colorectal adenoma after polypectomy  \nTsan-Hsuan Changa,b, Lee-Won Chonga,b,c, Hung-Chuen Changa,b,c, Yu-Hwa Liua,b, Cheuk-Kay Suna,b,c, Kou-Ching Yanga,b, Yu-Min Lina,b,c,*  \naDepartment of Internal Medicine, Shin Kong Wu Ho‐Su Memorial Hospital, Taipei, Taiwan, ROC; bDivision of Gastroenterology and Hepatology, Shin Kong Wu Ho‐Su Memorial Hospital, Taipei, Taiwan, ROC; cSchool of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan, ROC  \nAbstract  \nBackground: Adenoma recurrence following polypectomy remains a major clinical concern, necessitating the optimization of risk assessment strategies. This study explored key risk factors for metachronous advanced adenomas, focusing on metabolic factors and initial colonoscopic findings, to offer recommendations regarding risk stratification and surveillance.  \nMethods: This retrospective study included individuals who had undergone two colonoscopies between January 2014 and February 2020, with adenomas detected during the initial examination. The associations of various factors—such as age, sex, metabolic disorders, and baseline colonoscopic findings—with metachronous advanced adenomas were investigated.  \nResults: Of 33 073 individuals who underwent baseline colonoscopy, 2013 met the eligibility criteria. Multivariate analysis indicated that age of ≥45 years, male sex, and baseline colonoscopic findings were key predictors of metachronous advanced adenomas. The adjusted odds ratio (OR; 95% CI) values for metachronous advanced adenomas in patients with multiple (≥3) diminutive adenomas, those with multiple (≥3) small adenomas, and those with advanced adenomas were 1.56 (95% CI, 0.87-2.80), 3.27 (95% CI, 2.02-5.29), and 5.41 (95% CI, 3.73-7.83), respectively, compared with the results in patients with one or two nonadvanced adenomas.  \nConclusion: This study highlights the importance of baseline colonoscopy in identifying patients at elevated risk of developing metachronous advanced adenomas, particularly advanced adenomas. On the basis of our findings, we recommend integrating risk stratification by adenoma size, number, and histology into postpolypectomy surveillance guidelines. Personalized surveillance intervals informed by baseline findings and patient-specific risk factors may help clinicians optimize follow-up strategies and improve clinical outcomes.  \nKeywords: Advanced adenoma; Colonoscopy; Metachronous adenoma; Nonadvanced adenoma  \n538 [www.ejcma.org](www.ejcma.org)[ ](www.ejcma.org)\u003Cz10.1097/JCMA.0000000000001239>  \nOriginal Article. (2025) 88:7 J Chin MedAssoc  \nLay Summary: Adenomas are precancerous growths in the colon that can recur after removal. This study identified factors that increase the risk of developing more serious adenomas after initial colonoscopy and polypectomy. We examined a large group of people who had two colonoscopies over several years. We found that age, gender, and the type of adenomas detected in the first colonoscopy are key predictors of whether advanced adenomaswill develop. Specifically, people with multiple or larger adenomasin the first colonoscopy had a higher risk of recurrence. Based on these findings, we suggest a more personalized approach to monitoring patients after polypectomy, adjusting follow-up exams based on individual risk factors. This approach could improve long-term outcomes, making postpolypectomy surveillance more effective and reducing the risk of future colon health issues.  \n1. INTRODUCTION  \nColorectal cancer (CRC) remains a leading global cause of mortality despite therapeutic advancements.1 The adenoma–carcinoma sequence is the main driver of CRC development, which highlights the importance of colonoscopy in disease screening and prevention. Colonoscopy, particularly with adenoma removal, effectively reduces the risk of CRC-related mortality. Consequently, surveillance colonoscopy is recommended after initial adenoma removal becau","cbCaipbJi4XWV3Po","https://ap.wps.com/l/cbCaipbJi4XWV3Po","pdf",1508276,"English","# Introduction\n## Adenoma–carcinoma sequence and surveillance colonoscopy\n## Metabolic factors and recurrence risk\n# Methods\n## Study setting and cohort","[{\"question\":\"What was the main purpose of this study?\",\"answer\":\"To identify key risk factors for metachronous advanced colorectal adenomas after polypectomy, focusing on metabolic factors and initial colonoscopic findings to support risk stratification and surveillance recommendations.\"},{\"question\":\"How was the study conducted?\",\"answer\":\"It was a retrospective hospital-based study of individuals who had two colonoscopies between January 2014 and February 2020, with adenomas detected at the initial examination.\"},{\"question\":\"Which factors were identified as key predictors of metachronous advanced adenomas?\",\"answer\":\"Multivariate analysis indicated that age ≥45 years, male sex, and baseline colonoscopic findings were major predictors, especially advanced adenomas and multiple adenomas at baseline.\"}]","Predictors of metachronous advanced colorectal adenoma after polypectomy | PDF",1790664481,18]