[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-421570-105":59,"doc-detail-421570-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","physical-activity-complexity-and-cognitive-function-in-older-adults-abstract","PHYSICAL ACTIVITY COMPLEXITY AND COGNITIVE FUNCTION IN OLDER ADULTS - Abstract","","Physical activity is linked to cognitive impairment and dementia in older adults, yet most research emphasizes only PA quantities or intensities, which can add measurement error. This study evaluates PA complexity, a new accelerometer-based metric using multiscale entropy, and its association with cognitive function in older adults in the Connectomics in Brain Aging and Dementia study. Among 166 adults with valid 7-day wrist accelerometer data, confirmatory factor analysis formed memory, language, and executive function factors. Higher PA complexity showed positive associations with fluid and total cognition scores, especially at PA complexity ≤0.6 before adjustment, and remained significant after adjusting for sociodemographic characteristics. Lower PA complexity related to reduced factor scores across memory, language, and executive function. Findings support using novel PA metrics to detect subtle activity-pattern changes and aid prediction of early dementia progression.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/physical-activity-complexity-and-cognitive-function-in-older-adults-abstract/421570/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/physical-activity-complexity-and-cognitive-function-in-older-adults-abstract/421570.png","ImageObject",300,407,{"name":92,"@type":93},"Alex Sinclair","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is PA complexity and how is it measured in this study?","Question",{"text":112,"@type":113},"PA complexity is a novel physical activity metric derived from continuous accelerometer signals using the multiscale entropy method.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How many older adults were included in the final analysis?",{"text":117,"@type":113},"166 adults were included after requiring at least three valid days of accelerometer data with ≤10% non-wear time.",{"name":119,"@type":110,"acceptedAnswer":120},"What relationship did the study find between PA complexity and cognitive function?",{"text":121,"@type":113},"Higher PA complexity was associated with higher fluid and total cognition composite scores, while low PA complexity (≤0.6) was linked to lower factor scores for memory, language, and executive function.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},421570,1790762860,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":81,"preview_page_count":4},1099523882182,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","80 Innovation in Aging, 2025, Vol. 9, No. S2  \nAbstract citation ID: igaf122.267  \nPHYSICAL ACTIVITY COMPLEXITY AND COGNITIVE FUNCTION IN OLDER ADULTS  \nYurun Cai, Beth Snitz, and Ann Cohen, University of Pittsburgh, Pittsburgh, Pennsylvania, United States  \nPhysical activity (PA) is associated with cognitive impairment and dementia in older adults. However, most studies have focused solely on quantities or intensities (e.g., moderate to vigorous PA) which may introduce measurement error. This study aims to examine the association between a novel PA measure–PA complexity, derived from continuous accelerometer signals using multiscale entropy method–and cognitive function in older adults in the Connectomics in Brain Aging and Dementia study. Among  \n190 adults who completed neuropsychological tests and 7-day wrist-worn accelerometer assessment in 2016-2021, 166 (mean age=65.3±8.9y) had ≥3 valid days (≤10% non-wear time of the day) of accelerometer data and were included in the analysis. Confirmatory factor analysis was used to construct three factors (memory, language, and executive function) from neuropsychological tests. In the unadjusted piecewise linear regression models, every 0.1-unit higher in PA complexity was associated with a  \n3.2-unit (p = 0.004) higher fluid cognition composite score anda 2.7-unit (p = 0.008) higher total cognition composite score when PA complexity was ≤0.6 . After adjusting for sociodemographic characteristics and total activity counts per day, every  \n0.1-unit higher in PA complexity was associated with a 1.8-unit (p = 0.044) higher total cognition composite score. Low PA complexity (≤0.6) was associated with lower factor scores in memory (β=-0.26, p= 0.037), language (β=-0.33, p= 0.008), and executive function (β=-0.37, p = 0.004) . Our findings highlight the importance of assessing novel PA metrics which may be more sensitive than conventional metrics to identify subtle changes in activity patterns and help predict early stages of pathological progression to dementia.","cbCailyHXRviB4tV","https://ap.wps.com/l/cbCailyHXRviB4tV","pdf",138415,"English","# Study background and rationale\n# Methods and participants\n# Cognitive measures and statistical analysis\n# Key results\n# Implications and conclusions","[{\"question\":\"What is PA complexity and how is it measured in this study?\",\"answer\":\"PA complexity is a novel physical activity metric derived from continuous accelerometer signals using the multiscale entropy method.\"},{\"question\":\"How many older adults were included in the final analysis?\",\"answer\":\"166 adults were included after requiring at least three valid days of accelerometer data with ≤10% non-wear time.\"},{\"question\":\"What relationship did the study find between PA complexity and cognitive function?\",\"answer\":\"Higher PA complexity was associated with higher fluid and total cognition composite scores, while low PA complexity (≤0.6) was linked to lower factor scores for memory, language, and executive function.\"}]","PHYSICAL ACTIVITY COMPLEXITY AND COGNITIVE FUNCTION IN OLDER ADULTS - Abstract | PDF",1790625155]