[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-35829":3,"doc-seo-35829":29},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":20,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":13,"seo_description":14,"update_tm":27,"read_time":28},35829,13056703020460,"Valentina","https://ap-avatar.wpscdn.com/avatar/be000253dac470eee5d?_k=1778207105932848923",8,"Research & Report","pH Sensitive Metal Organic Frameworks for the Improved Inhibition of HepG2 Cell via Folate Receptor Mediated Targeting and Cascaded CDT Effect","pH-sensitive metal–organic frameworks are developed to enhance inhibition of HepG2 cells by combining folate-receptor-mediated targeting with a cascaded chemodynamic therapy (CDT) mechanism in the tumor microenvironment. The strategy integrates pH-responsive targeted drug delivery to improve accumulation and therapeutic action specifically within TME conditions. The work is presented as a research article with explicit study metadata including citation details, corresponding authors, and formal reception timeline, and it lists therapy-relevant keywords.","","cbCaisYNyCg3Lsxf","https://ap.wps.com/l/cbCaisYNyCg3Lsxf","pdf",4005627,1,16,"English","en",105,"# Research Article Overview\n# Title and Author Information\n# Correspondence and Publication Timeline\n# Keywords","[{\"question\":\"What is the purpose of the pH-sensitive metal–organic frameworks in this study?\",\"answer\":\"To improve inhibition of HepG2 cells by exploiting pH-responsive behavior for targeted therapeutic action in the tumor microenvironment.\"},{\"question\":\"How does folate receptor-mediated targeting contribute to the treatment strategy?\",\"answer\":\"It enables the delivery system to target HepG2 cells more specifically by using folate receptor recognition to guide accumulation at tumor sites.\"},{\"question\":\"What therapeutic mechanism is emphasized by the “cascaded CDT effect”?\",\"answer\":\"A cascaded chemodynamic therapy (CDT) effect is used to strengthen the therapeutic outcome under tumor microenvironment conditions, as reflected in the listed keywords.\"}]",1782594743,40,null]