[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-425142-105":59,"doc-detail-425142-en":124},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":117,"head_meta":119,"extra_data":121,"updated_unix":123},105,"en","personality-and-incident-disabling-dementia-among-community-dwelling-older-adults-a-20-year-longitudinal-study","PERSONALITY AND INCIDENT DISABLING DEMENTIA AMONG COMMUNITY-DWELLING OLDER ADULTS - A 20-YEAR LONGITUDINAL STUDY","","This 20-year longitudinal study examines how personality relates to the onset of incident disabling dementia among community-dwelling older adults. Using 898 participants aged 65–84 from the National Institute for Longevity Sciences-Longitudinal Study of Aging, baseline personality was captured at the first questionnaire response, excluding those with baseline cognitive impairment. Disabling dementia was defined using rank criteria from a doctor’s opinion framework. Cox proportional hazards models adjusted for a wide range of demographic, clinical, lifestyle, social, and genetic (APOE ε4) factors. Over 12.3 years follow-up, 196 individuals developed disabling dementia.",{"@graph":69,"@context":116},[70,84,99],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/personality-and-incident-disabling-dementia-among-community-dwelling-older-adults-a-20-year-longitudinal-study/425142/",{"url":83,"name":65,"@type":85,"author":86,"headline":65,"publisher":89,"fileFormat":92,"inLanguage":63,"description":67,"dateModified":93,"datePublished":93,"encodingFormat":92,"isAccessibleForFree":94,"interactionStatistic":95},"DigitalDocument",{"name":87,"@type":88},"Himbo","Person",{"url":74,"name":90,"@type":91},"DocShare","Organization","application/pdf","2026-09-28",true,{"@type":96,"interactionType":97,"userInteractionCount":4},"InteractionCounter",{"@type":98},"ViewAction",{"@type":100,"mainEntity":101},"FAQPage",[102,108,112],{"name":103,"@type":104,"acceptedAnswer":105},"What was the study trying to determine?","Question",{"text":106,"@type":107},"The study examined the effect of personality on incident disabling dementia in community-dwelling older adults.","Answer",{"name":109,"@type":104,"acceptedAnswer":110},"How were personality and disabling dementia measured?",{"text":111,"@type":107},"Personality was assessed with the NEO Five-Factor Inventory, and disabling dementia was defined using rank criteria from an “Independence Degree in Daily Living for Older adults with Dementia” based on a doctor’s opinion framework.",{"name":113,"@type":104,"acceptedAnswer":114},"What did the results show about openness and conscientiousness?",{"text":115,"@type":107},"Openness was negatively associated with overall incident disabling dementia risk. In stratified analyses, openness reduced risk in APOE ε4 non-carriers, while conscientiousness reduced risk in APOE ε4 carriers.","https://schema.org",{"og:url":83,"og:type":118,"og:title":65,"og:site_name":90,"og:description":67},"article",{"robots":120,"canonical":83},"index,follow",{"doc_id":122,"site_id":62},425142,1790636377,{"code":4,"msg":5,"data":125},{"doc_id":122,"user_id":126,"nickname":87,"user_avatar":127,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":128,"file_id":129,"file_url":130,"file_type":131,"file_size":132,"view_count":4,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":14,"language":133,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":134,"faqs":135,"seo_title":136,"seo_description":67,"update_tm":123,"read_time":24},687197100911,"https://ap-avatar.wpscdn.com/avatar/a000239b6f1da00475?x-image-process=image/resize,m_fixed,w_180,h_180&k=1785132997149421697","Innovation in Aging, 2025, Vol. 9, No. S2 863  \nAbstract citation ID: igaf122.2923  \nPERSONALITY AND INCIDENT DISABLING DEMENTIA AMONG COMMUNITY-DWELLING OLDER ADULTS: A 20-YEAR LONGITUDINAL STUDY  \nYukiko Nishita1, Chikako Tange1, Shu Zhang1, Sayaka  \nKubota1, Mana Tateishi1, Fujiko Ando2, Hiroshi Shimokata3,  \n864 Innovation in Aging, 2025, Vol. 9, No. S2  \nand Rei Otsuka1, 1. National Center for Geriatrics and Gerontology, Obu, Aichi, Japan, 2. Aichi Shukutoku University, Nagakute, Aichi, Japan, 3. Nagoya University of Arts and Sciences, Nisshin, Aichi, Japan  \nObjectives: This study examines the effect of personality on incident disabling dementia in community-dwelling older adults.  \nMethods: We analyzed 898 adults (65 − 84 years) from the National Institute for Longevity Sciences-Longitudinal Study of Aging 2nd (2000 − 2002) or 5th (2006 − 2008) waves, with baseline established at their first personality questionnaire response.  \nParticipants with baseline cognitive impairment (MMSE ≤ 23), incident disabling dementia before baseline or within five follow-up years were excluded. Personality was assessed using NEO Five-Factor Inventory, measuring neuroticism, extraversion, openness, agreeableness, and conscientiousness. Disabling dementia was defined as ≥ rank II on the “Independence Degree in Daily Living for Older adults with Dementia” based on Doctor’s Opinion Paper (from baseline to January 2022) . Cox proportional hazards models estimated adjusted hazard ratios (aHR) and 95% confidence intervals (CI) for one standard deviation (SD) increase of personalities, controlling for age, sex, education, hearing and vision impairment, LDL cholesterol, depressive symptoms, physical activity, history of diabetes and hypertension, smoking, alcohol drinking, body mass index, social isolation, APOE ε4, and survey wave. A stratified analysis of APOE ε4 was also conducted. Results: Over a mean (SD) follow-up of 12.3 (5.8) years, 196 individuals (21.8%) developed disabling dementia. Openness was negatively associated with overall incident disabling dementia risk (aHR [95%CI]: 0.82 [0.70–0.96]) . Stratified analysis showed that openness reduced dementia risk in ε4 non-carriers (0 .79 [0 .67–0.94]), while conscientiousness reduced it in ε4 carriers (0 .56 [0 .37–0. 84]) .  \nConclusion: Openness may reduce incident disabling dementia risk, while conscientiousness might suppress disabling dementia onset in ε4 carriers.","cbCaieBZDNVRt71T","https://ap.wps.com/l/cbCaieBZDNVRt71T","pdf",1513953,"English","# Objectives\n## Methods\n## Results\n## Conclusion","[{\"question\":\"What was the study trying to determine?\",\"answer\":\"The study examined the effect of personality on incident disabling dementia in community-dwelling older adults.\"},{\"question\":\"How were personality and disabling dementia measured?\",\"answer\":\"Personality was assessed with the NEO Five-Factor Inventory, and disabling dementia was defined using rank criteria from an “Independence Degree in Daily Living for Older adults with Dementia” based on a doctor’s opinion framework.\"},{\"question\":\"What did the results show about openness and conscientiousness?\",\"answer\":\"Openness was negatively associated with overall incident disabling dementia risk. In stratified analyses, openness reduced risk in APOE ε4 non-carriers, while conscientiousness reduced risk in APOE ε4 carriers.\"}]","PERSONALITY AND INCIDENT DISABLING DEMENTIA AMONG COMMUNITY-DWELLING OLDER ADULTS - A 20-YEAR LONGITUDINAL STUDY | PDF"]