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The report presents objectives, methods, and results including procedural metrics and follow-up outcomes, with statistical comparisons of efficacy and safety endpoints. The analysis discusses device-related performance, relevant clinical criteria, and subgroup information, reporting significance thresholds and confidence intervals to interpret effectiveness. Conclusions summarize the observed outcomes and provide context for complication rates and overall feasibility.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/percutaneous-left-atrial-appendage-closure-with-concomitant-dual-device-implantation-a-single-center/444518/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/percutaneous-left-atrial-appendage-closure-with-concomitant-dual-device-implantation-a-single-center/444518.png","ImageObject",300,407,{"name":92,"@type":93},"Aran","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the study about?","Question",{"text":112,"@type":113},"The study focuses on percutaneous left atrial appendage closure performed together with concomitant dual-device implantation at a single center.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were outcomes evaluated?",{"text":117,"@type":113},"Outcomes were evaluated using reported objective endpoints and follow-up results, with statistical testing including significance thresholds and confidence intervals.",{"name":119,"@type":110,"acceptedAnswer":120},"What types of results are presented?",{"text":121,"@type":113},"The document reports both efficacy-related outcomes and safety/complication-related findings, along with subgroup information such as age categories and patient characteristics.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},444518,1790763203,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},137455076865,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","TY􀀁E 􀀌􀀋􀀇􀀛􀀇􀀍􀀅􀀒 􀀝􀀐􀀃􀀐􀀅􀀋􀀞h  \n􀀁UBLISHED 19 D􀀐􀀞􀀐􀀙􀀚􀀐􀀋 2025 DOI 10.3389/f􀀞 􀀙 .2025.1692521  \n􀀁􀀂􀀃􀀄􀀁􀀂 􀀆􀀇  \n􀀁􀀂􀀃􀀄􀀅􀀆􀀂􀀇􀀈 􀀊􀀅􀀋􀀇􀀅 􀀌􀀍􀀈􀀋􀀅􀀄􀀈􀀎  \n􀀌􀀃􀀏􀀐􀀑􀀅􀀒􀀐 􀀓􀀅􀀒􀀐􀀅􀀔􀀔􀀇 􀀕 􀀖􀀅􀀍􀀄􀀗􀀘􀀙􀀚􀀋􀀈􀀛􀀇􀀈􀀎 􀀜􀀃􀀄􀀇􀀄􀀂􀀄􀀈 􀀑􀀇􀀝􀀇􀀞􀀈 􀀐􀀋􀀈 􀀐 C􀀂􀀋􀀅 􀀅 C􀀅􀀋􀀅􀀄􀀄􀀐􀀋􀀐 􀀖􀀞􀀇􀀐􀀍􀀄􀀇fi􀀞􀀈(􀀜.􀀝.C.C.􀀖.)􀀎 􀀜􀀄􀀅􀀒y  \n􀀈􀀁􀀉􀀃􀀁􀀊􀀁􀀂 􀀆􀀇  \n􀀊􀀅􀀃􀀅􀀄􀀈 F􀀂k􀀂􀀍􀀅􀀛􀀅􀀎 K􀀈k􀀂􀀋􀀅 􀀊􀀐􀀙􀀈􀀋􀀇􀀅􀀒 H􀀈􀀃􀀏􀀇􀀄􀀅􀀒􀀎 J􀀅􀀏􀀅􀀍 Q􀀇 Z􀀈􀀂􀀎  \nL􀀅􀀍􀀔h􀀈􀀂 U􀀍􀀇 􀀐􀀋􀀃􀀇􀀄y 􀀖􀀐􀀞􀀈􀀍􀀑 H􀀈􀀃􀀏􀀇􀀄􀀅􀀒􀀎 Ch􀀇􀀍􀀅  \n*􀀋􀀌􀀈􀀈􀀁􀀍􀀎􀀌􀀏􀀂􀀁􀀏􀀋􀀁  \nL􀀈􀀋􀀐􀀍􀀔 􀀝ä􀀚􀀐􀀋  \n 􀀒􀀈􀀋􀀐􀀍􀀔 . 􀀋􀀅􀀐􀀚􀀐􀀋@􀀇􀀍􀀃􀀐􀀒 .􀀞h  \n􀀈􀀁􀀋􀀁􀀃􀀉􀀁􀀂 25 􀀘􀀂􀀛􀀂􀀃􀀄 2025  \n􀀈􀀁􀀉􀀃􀀍􀀁􀀂 29 N􀀈 􀀐􀀙􀀚􀀐􀀋 2025  \n􀀐􀀋􀀋􀀁􀀎􀀄􀀁􀀂 30 N􀀈 􀀐􀀙􀀚􀀐􀀋 2025  \n􀀎􀀑􀀆􀀒􀀃􀀍􀀓􀀁􀀂 19 D􀀐􀀞􀀐􀀙􀀚􀀐􀀋 2025  \n􀀋􀀌􀀈􀀈􀀁􀀋􀀄􀀁􀀂 23 D􀀐􀀞􀀐􀀙􀀚􀀐􀀋 2025  \n􀀋􀀃􀀄􀀐􀀄􀀃􀀌􀀏  \n􀀓􀀅􀀃y􀀃 􀀘􀀎 􀀓􀀅􀀒􀀐􀀅 􀀝􀀎 B􀀇􀀍􀀇 T􀀎 P􀀐􀀋􀀇􀀞h􀀕K􀀋􀀃􀀍􀀇k J􀀎􀀓􀀅􀀙􀀅􀀋􀀑􀀐􀀒􀀒􀀅 􀀊􀀎 􀀝􀀈􀀄􀀐􀀍 L􀀎 􀀖􀀇􀀈􀀍􀀄􀀇􀀃 􀀓C􀀊􀀎 􀀊􀀐􀀇􀀐􀀋 B  \n􀀅􀀍􀀑 􀀝ä􀀚􀀐􀀋 L (2025) P􀀐􀀋􀀞􀀂􀀄􀀅􀀍􀀐􀀈􀀂􀀃 􀀒􀀐f􀀄 􀀅􀀄􀀋􀀇􀀅􀀒􀀅􀀏􀀏􀀐􀀍􀀑􀀅􀀛􀀐 􀀞􀀒􀀈􀀃􀀂􀀋􀀐 w􀀇􀀄h 􀀞􀀈􀀍􀀞􀀈􀀙􀀇􀀄􀀅􀀍􀀄 􀀑􀀂􀀅􀀒􀀕􀀑􀀐 􀀇􀀞􀀐 􀀇􀀙􀀏􀀒􀀅􀀍􀀄􀀅􀀄􀀇􀀈􀀍: 􀀅 􀀃􀀇􀀍􀀛􀀒􀀐􀀕􀀞􀀐􀀍􀀄􀀐􀀋􀀈􀀚􀀃􀀐􀀋 􀀅􀀄􀀇􀀈􀀍􀀅􀀒 􀀃􀀄􀀂􀀑y.  \nF􀀋􀀈􀀍􀀄 . C􀀅􀀋􀀑􀀇􀀈 􀀅􀀃􀀞 . 􀀊􀀐􀀑 . 12:1692521 .􀀑􀀈􀀇: 10.3389/f􀀞 􀀙 .2025.1692521  \n􀀋􀀌􀀎􀀇􀀈􀀃􀀔􀀓􀀄  \n© 2025 􀀓􀀅􀀃y􀀃􀀎 􀀓􀀅􀀒􀀐􀀅􀀎 B􀀇􀀍􀀇􀀎 P􀀐􀀋􀀇􀀞h􀀕K􀀋􀀃􀀍􀀇k􀀎􀀓􀀅􀀙􀀅􀀋􀀑􀀐􀀒􀀒􀀅􀀎 􀀝􀀈􀀄􀀐􀀍􀀎 􀀖􀀇􀀈􀀍􀀄􀀇􀀃􀀎 􀀊􀀐􀀇􀀐􀀋 􀀅􀀍􀀑 􀀝ä􀀚􀀐􀀋 . Th􀀇􀀃 􀀇􀀃 􀀅􀀍 􀀈􀀏􀀐􀀍􀀕􀀅􀀞􀀞􀀐􀀃􀀃 􀀅􀀋􀀄􀀇􀀞􀀒􀀐 􀀑􀀇􀀃􀀄􀀋􀀇􀀚􀀂􀀄􀀐􀀑􀀂􀀍􀀑􀀐􀀋 􀀄h􀀐 􀀄􀀐􀀋􀀙􀀃 􀀈f 􀀄h􀀐 C􀀋􀀐􀀅􀀄􀀇 􀀐 C􀀈􀀙􀀙􀀈􀀍􀀃􀀘􀀄􀀄􀀋􀀇􀀚􀀂􀀄􀀇􀀈􀀍 L􀀇􀀞􀀐􀀍􀀃􀀐 (CC BY) . Th􀀐 􀀂􀀃􀀐􀀎􀀑􀀇􀀃􀀄􀀋􀀇􀀚􀀂􀀄􀀇􀀈􀀍 􀀈􀀋 􀀋􀀐􀀏􀀋􀀈􀀑􀀂􀀞􀀄􀀇􀀈􀀍 􀀇􀀍 􀀈􀀄h􀀐􀀋 f􀀈􀀋􀀂􀀙􀀃 􀀇􀀃􀀏􀀐􀀋􀀙􀀇􀀄􀀄􀀐􀀑􀀎 􀀏􀀋􀀈 􀀇􀀑􀀐􀀑 􀀄h􀀐 􀀈􀀋􀀇􀀛􀀇􀀍􀀅􀀒 􀀅􀀂􀀄h􀀈􀀋(􀀃) 􀀅􀀍􀀑􀀄h􀀐 􀀞􀀈􀀏y􀀋􀀇􀀛h􀀄 􀀈w􀀍􀀐􀀋(􀀃) 􀀅􀀋􀀐 􀀞􀀋􀀐􀀑􀀇􀀄􀀐􀀑 􀀅􀀍􀀑 􀀄h􀀅􀀄  \n􀀄h􀀐 􀀈􀀋􀀇􀀛􀀇􀀍􀀅􀀒 􀀏􀀂􀀚􀀒􀀇􀀞􀀅􀀄􀀇􀀈􀀍 􀀇􀀍 􀀄h􀀇􀀃 j􀀈􀀂􀀋􀀍􀀅􀀒 􀀇􀀃 􀀞􀀇􀀄􀀐􀀑􀀎􀀇􀀍 􀀅􀀞􀀞􀀈􀀋􀀑􀀅􀀍􀀞􀀐 w􀀇􀀄h 􀀅􀀞􀀞􀀐􀀏􀀄􀀐􀀑 􀀅􀀞􀀅􀀑􀀐􀀙􀀇􀀞􀀏􀀋􀀅􀀞􀀄􀀇􀀞􀀐 . N􀀈 􀀂􀀃􀀐􀀎 􀀑􀀇􀀃􀀄􀀋􀀇􀀚􀀂􀀄􀀇􀀈􀀍 􀀈􀀋 􀀋􀀐􀀏􀀋􀀈􀀑􀀂􀀞􀀄􀀇􀀈􀀍􀀇􀀃 􀀏􀀐􀀋􀀙􀀇􀀄􀀄􀀐􀀑 wh􀀇􀀞h 􀀑􀀈􀀐􀀃 􀀍􀀈􀀄 􀀞􀀈􀀙􀀏􀀒y w􀀇􀀄h  \n􀀄h􀀐􀀃􀀐 􀀄􀀐􀀋􀀙􀀃 .  \n􀀁􀀂􀀃􀀄􀀅􀀆􀀇􀀈􀀂􀀉􀀅􀀊 􀀌􀀂􀀍􀀆 􀀇􀀆􀀃􀀎􀀇􀀌􀀇􀀏􀀏􀀂􀀈􀀐􀀇􀀑􀀂 􀀄􀀌􀀉􀀊􀀅􀀃􀀂 􀀒􀀎􀀆􀀓􀀄􀀉􀀈􀀄􀀉􀀔􀀎􀀆􀀇􀀈􀀆 􀀐􀀅􀀇􀀌􀀕􀀐􀀂􀀖􀀎􀀄􀀂􀀎􀀔􀀏􀀌􀀇􀀈􀀆􀀇􀀆􀀎􀀉􀀈􀀗 􀀇 􀀊􀀎􀀈􀀑􀀌􀀂􀀕􀀄􀀂􀀈􀀆􀀂􀀃􀀉􀀘􀀊􀀂􀀃􀀖􀀇􀀆􀀎􀀉􀀈􀀇􀀌 􀀊􀀆􀀅􀀐􀀙  \n􀀚􀀈􀀆􀀇􀀈􀀇􀀊 􀀛􀀇􀀊􀀙􀀊􀀜􀀝 􀀞􀀉􀀘􀀂􀀃􀀆􀀉 􀀛􀀇􀀌􀀂􀀇 􀀜􀀝 􀀝 T􀀉􀀔􀀔􀀇􀀊􀀉 B􀀎􀀈􀀎 􀀜􀀝3 􀀝 J􀀅􀀇􀀈 􀀁􀀂􀀃􀀎􀀄􀀓􀀕K􀀃􀀊􀀈􀀎k􀀜􀀝 M􀀇􀀃􀀄􀀉 􀀛􀀇􀀔􀀇􀀃􀀐􀀂􀀌􀀌􀀇 􀀜􀀝 L􀀇􀀅􀀃􀀂􀀈􀀆 􀀞􀀉􀀆􀀂􀀈 􀀜􀀝􀀛􀀂􀀉􀀃􀀑􀀂 C. M. S􀀎􀀉􀀈􀀆􀀎􀀊􀀜􀀝 B􀀂􀀃􀀈􀀓􀀇􀀃􀀐 M􀀂􀀎􀀂􀀃􀀜 􀀇􀀈􀀐 L􀀉􀀃􀀂􀀈z 􀀞ä􀀘􀀂􀀃􀀜*  \n1 D􀀐􀀏􀀅􀀋􀀄􀀙􀀐􀀍􀀄 􀀈f C􀀅􀀋􀀑􀀇􀀈􀀒􀀈􀀛y􀀎 B􀀐􀀋􀀍 U􀀍􀀇 􀀐􀀋􀀃􀀇􀀄y H􀀈􀀃􀀏􀀇􀀄􀀅􀀒􀀎 U􀀍􀀇 􀀐􀀋􀀃􀀇􀀄y 􀀈f B􀀐􀀋􀀍􀀎 B􀀐􀀋􀀍􀀎 􀀖w􀀇􀀄􀀔􀀐􀀋􀀒􀀅􀀍􀀑􀀎 2 D􀀐􀀏􀀅􀀋􀀄􀀙􀀐􀀍􀀄 􀀈f C􀀅􀀋􀀑􀀇􀀈􀀒􀀈􀀛y􀀎 H􀀈􀀃􀀏􀀇􀀄􀀅􀀒 C􀀐􀀍􀀄􀀋􀀐 􀀈f B􀀇􀀐􀀒􀀎 B􀀇􀀐􀀒􀀎 􀀖w􀀇􀀄􀀔􀀐􀀋􀀒􀀅􀀍􀀑􀀎 3􀀓􀀋􀀅􀀑􀀂􀀅􀀄􀀐 􀀖􀀞h􀀈􀀈􀀒 f􀀈􀀋 H􀀐􀀅􀀒􀀄h 􀀖􀀞􀀇􀀐􀀍􀀞􀀐􀀃􀀎 U􀀍􀀇 􀀐􀀋􀀃􀀇􀀄y 􀀈f B􀀐􀀋􀀍􀀎 B􀀐􀀋􀀍􀀎 􀀖w􀀇􀀄􀀔􀀐􀀋􀀒􀀅􀀍􀀑  \n􀀆􀀕􀀖􀀗􀀘􀀙􀀚􀀛􀀜􀀝􀀞 P􀀐􀀋􀀞􀀂􀀄􀀅􀀍􀀐􀀈􀀂􀀃 􀀒􀀐f􀀄 􀀅􀀄􀀋􀀇􀀅􀀒 􀀅􀀏􀀏􀀐􀀍􀀑􀀅􀀛􀀐 (L􀀘􀀘) 􀀞􀀒􀀈􀀃􀀂􀀋􀀐 (L􀀘􀀘C) 􀀇􀀃 􀀅 􀀏􀀋􀀈 􀀐􀀍􀀃􀀄􀀋􀀈k􀀐 􀀏􀀋􀀐 􀀐􀀍􀀄􀀇􀀈􀀍 􀀃􀀄􀀋􀀅􀀄􀀐􀀛y f􀀈􀀋 􀀏􀀅􀀄􀀇􀀐􀀍􀀄􀀃 w􀀇􀀄h 􀀅􀀄􀀋􀀇􀀅􀀒 fi􀀚􀀋􀀇􀀒􀀒􀀅􀀄􀀇􀀈􀀍 (􀀘F) . H􀀈w􀀐 􀀐􀀋􀀎􀀇􀀍􀀞􀀈􀀙􀀏􀀒􀀐􀀄􀀐 􀀃􀀐􀀅􀀒􀀇􀀍􀀛 􀀇􀀍 􀀞􀀈􀀙􀀏􀀒􀀐x L􀀘􀀘 􀀅􀀍􀀅􀀄􀀈􀀙􀀇􀀐􀀃 􀀙􀀅y 􀀞􀀈􀀙􀀏􀀋􀀈􀀙􀀇􀀃􀀐 􀀐ffi􀀞􀀅􀀞y.  \n􀀌 je􀀖tives􀀞 Th􀀇􀀃 􀀃􀀄􀀂􀀑y 􀀐 􀀅􀀒􀀂􀀅􀀄􀀐􀀃 􀀄h􀀐 􀀃􀀅f􀀐􀀄y􀀎 f􀀐􀀅􀀃􀀇􀀚􀀇􀀒􀀇􀀄y􀀎 􀀅􀀍􀀑 􀀐ffi􀀞􀀅􀀞y 􀀈f 􀀞􀀈􀀍􀀞􀀈􀀙􀀇􀀄􀀅􀀍􀀄 􀀑􀀂􀀅􀀒􀀕􀀑􀀐 􀀇􀀞􀀐 L􀀘􀀘C 􀀇􀀍 􀀙􀀂􀀒􀀄􀀇􀀒􀀈􀀚􀀐􀀑 􀀅􀀍􀀅􀀄􀀈􀀙􀀇􀀐􀀃􀀎 􀀋􀀐􀀏􀀋􀀐􀀃􀀐􀀍􀀄􀀇􀀍􀀛 􀀄h􀀐􀀒􀀅􀀋􀀛􀀐􀀃􀀄 􀀞􀀈h􀀈􀀋􀀄 􀀐x􀀅􀀙􀀇􀀍􀀐􀀑 􀀄􀀈 􀀑􀀅􀀄􀀐 .  \nMeth􀀚􀀝s􀀞 W􀀐 􀀋􀀐 􀀇􀀐w􀀐􀀑 􀀅􀀒􀀒 L􀀘􀀘C 􀀏􀀋􀀈􀀞􀀐􀀑􀀂􀀋􀀐􀀃 􀀏􀀐􀀋f􀀈􀀋􀀙􀀐􀀑 􀀅􀀄 􀀄h􀀐 U􀀍􀀇 􀀐􀀋􀀃􀀇􀀄y H􀀈􀀃􀀏􀀇􀀄􀀅􀀒 􀀈f B􀀐􀀋􀀍 􀀚􀀐􀀄w􀀐􀀐􀀍 2009 􀀅􀀍􀀑 2025 . B􀀅􀀃􀀐􀀒􀀇􀀍􀀐 􀀞h􀀅􀀋􀀅􀀞􀀄􀀐􀀋􀀇􀀃􀀄􀀇􀀞􀀃􀀎 􀀏􀀋􀀈􀀞􀀐􀀑􀀂􀀋􀀅􀀒􀀑􀀐􀀄􀀅􀀇􀀒􀀃􀀎 􀀅􀀍􀀑 f􀀈􀀒􀀒􀀈w􀀕􀀂􀀏 􀀑􀀅􀀄􀀅 w􀀐􀀋􀀐 􀀅􀀍􀀅􀀒y􀀔􀀐􀀑 f􀀈􀀋 􀀏􀀅􀀄􀀇􀀐􀀍􀀄􀀃 􀀋􀀐􀀞􀀐􀀇 􀀇􀀍􀀛 􀀑􀀂􀀅􀀒􀀕􀀑􀀐 􀀇􀀞􀀐 L􀀘􀀘C. 􀀁􀀍􀀑􀀏􀀈􀀇􀀍􀀄􀀃 􀀇􀀍􀀞􀀒􀀂􀀑􀀐􀀑 􀀄􀀐􀀞h􀀍􀀇􀀞􀀅􀀒 􀀃􀀂􀀞􀀞􀀐􀀃􀀃􀀎 􀀞􀀈􀀙􀀏􀀒􀀇􀀞􀀅􀀄􀀇􀀈􀀍􀀃􀀎 􀀄h􀀋􀀈􀀙􀀚􀀈􀀐􀀙􀀚􀀈􀀒􀀇􀀞􀀐 􀀐􀀍􀀄􀀃􀀎 􀀅􀀍􀀑 􀀑􀀐 􀀇􀀞􀀐􀀕􀀋􀀐􀀒􀀅􀀄􀀐􀀑 􀀇􀀃􀀃􀀂􀀐􀀃 . C􀀈􀀍􀀄􀀇􀀍􀀂􀀈􀀂􀀃 􀀑􀀅􀀄􀀅 w􀀐􀀋􀀐 􀀐x􀀏􀀋􀀐􀀃􀀃􀀐􀀑 􀀅􀀃􀀙􀀐􀀅􀀍 ± 􀀃􀀄􀀅􀀍􀀑􀀅􀀋􀀑 􀀑􀀐 􀀇􀀅􀀄􀀇􀀈􀀍 􀀈􀀋 􀀙􀀐􀀑􀀇􀀅􀀍 􀀅􀀒􀀂􀀐􀀃􀀎 wh􀀇􀀒􀀐 􀀞􀀅􀀄􀀐􀀛􀀈􀀋􀀇􀀞􀀅􀀒 􀀑􀀅􀀄􀀅 w􀀐􀀋􀀐􀀋􀀐􀀏􀀈􀀋􀀄􀀐􀀑 􀀅􀀃 􀀏􀀐􀀋􀀞􀀐􀀍􀀄􀀅􀀛􀀐􀀃 . 􀀓􀀋􀀈􀀂􀀏 􀀞􀀈􀀙􀀏􀀅􀀋􀀇􀀃􀀈􀀍􀀃 w􀀐􀀋􀀐 􀀞􀀈􀀍􀀑􀀂􀀞􀀄􀀐􀀑 􀀂􀀃􀀇􀀍􀀛 􀀁􀀕􀀄􀀐􀀃􀀄􀀎􀀊􀀅􀀍􀀍–Wh􀀇􀀄􀀍􀀐y 􀀂 􀀄􀀐􀀃􀀄􀀎 􀀈􀀋 􀀞h􀀇􀀕􀀃􀀆􀀂􀀅􀀋􀀐 􀀄􀀐􀀃􀀄 . D􀀇ff􀀐􀀋􀀐􀀍􀀞􀀐􀀃 w􀀐􀀋􀀐 􀀐x􀀏􀀋􀀐􀀃􀀃􀀐􀀑 􀀅􀀃 95%􀀞􀀈􀀍fi􀀑􀀐􀀍􀀞􀀐 􀀇􀀍􀀄􀀐􀀋 􀀅􀀒􀀃􀀎 􀀅􀀍􀀑 􀀅 􀀄 􀀕 􀀅􀀒􀀂􀀐 􀀈f 􀀒􀀐􀀃􀀃 􀀄h􀀅􀀍 0 . 05 w􀀅􀀃 􀀞􀀈􀀍􀀃􀀇􀀑􀀐􀀋􀀐􀀑 􀀃􀀇􀀛􀀍􀀇fi􀀞􀀅􀀍􀀄 .  \n􀀈es􀀛lts􀀞 􀀌f 1􀀎307 L􀀘􀀘C 􀀏􀀋􀀈􀀞􀀐􀀑􀀂􀀋􀀐􀀃􀀎 10 􀀇􀀍􀀞􀀒􀀂􀀑􀀐􀀑 􀀑􀀂􀀅􀀒􀀕􀀑􀀐 􀀇􀀞􀀐 􀀇􀀙􀀏􀀒􀀅􀀍􀀄􀀅􀀄􀀇􀀈􀀍 . Th􀀐􀀙􀀐􀀅􀀍 􀀅􀀛􀀐 􀀈f 􀀄h􀀐 􀀏􀀅􀀄􀀇􀀐􀀍􀀄􀀃 w􀀅􀀃 71 y􀀐􀀅􀀋􀀃􀀎 􀀅􀀍􀀑 􀀅􀀒􀀒 􀀏􀀅􀀄􀀇􀀐􀀍􀀄􀀃 w􀀐􀀋􀀐 􀀙􀀐􀀍 . Th􀀐 C􀀈􀀍􀀛􀀐􀀃􀀄􀀇 􀀐 h􀀐􀀅􀀋􀀄 f􀀅􀀇􀀒􀀂􀀋􀀐􀀎 Hy􀀏􀀐􀀋􀀄􀀐􀀍􀀃􀀇􀀈􀀍􀀎 􀀘􀀛􀀐 ≥75 y􀀐􀀅􀀋􀀃􀀎 D􀀇􀀅􀀚􀀐􀀄􀀐􀀃 􀀙􀀐􀀒􀀒􀀇􀀄􀀂􀀃􀀎 􀀏􀀋􀀇􀀈􀀋􀀖􀀄􀀋􀀈k􀀐 􀀈􀀋 T􀀜􀀘􀀎 V􀀅􀀃􀀞􀀂􀀒􀀅􀀋 􀀑􀀇􀀃􀀐􀀅􀀃􀀐􀀎 􀀘􀀛􀀐 65–74 y􀀐􀀅􀀋􀀃􀀎 􀀖􀀐x 􀀞􀀅􀀄􀀐􀀛􀀈􀀋y (CH􀀘2 D􀀖 2 􀀕 V􀀘􀀖􀀞) 􀀅􀀍􀀑 Hy􀀏􀀐􀀋􀀄􀀐􀀍􀀃􀀇􀀈􀀍􀀎 􀀘􀀚􀀍􀀈􀀋􀀙􀀅􀀒 􀀋􀀐􀀍􀀅􀀒/􀀒􀀇 􀀐􀀋 f􀀂􀀍􀀞􀀄􀀇􀀈􀀍􀀎 􀀖􀀄􀀋􀀈k􀀐􀀎 B􀀒􀀐􀀐􀀑􀀇􀀍􀀛 h􀀇􀀃􀀄􀀈􀀋y 􀀈􀀋 􀀏􀀋􀀐􀀑􀀇􀀃􀀏􀀈􀀃􀀇􀀄􀀇􀀈􀀍􀀎 L􀀅􀀚􀀇􀀒􀀐 􀀜N􀀝􀀎 􀀁􀀒􀀑􀀐􀀋􀀒y􀀎 D􀀋􀀂􀀛􀀃/􀀅􀀒􀀞􀀈h􀀈􀀒 (H􀀘􀀖􀀕BL􀀁D)􀀃􀀞􀀈􀀋􀀐􀀃 w􀀐􀀋􀀐 3 . 5 ± 1 . 8 􀀅􀀍􀀑 2 . 9 ± 1 .4􀀎 􀀋􀀐􀀃􀀏􀀐􀀞􀀄􀀇 􀀐􀀒y. 􀀊􀀈􀀃􀀄 􀀏􀀅􀀄􀀇􀀐􀀍􀀄􀀃 (70%) h􀀅􀀑􀀏􀀅􀀋􀀈xy􀀃􀀙􀀅􀀒 􀀘F. P􀀋􀀐􀀏􀀋􀀈􀀞􀀐􀀑􀀂􀀋􀀅􀀒 􀀅􀀍􀀑 􀀇􀀍􀀄􀀋􀀅􀀏􀀋􀀈􀀞􀀐􀀑􀀂􀀋􀀅􀀒 􀀄􀀋􀀅􀀍􀀃􀀐􀀃􀀈􀀏h􀀅􀀛􀀐􀀅􀀒􀀐􀀞h􀀈􀀞􀀅􀀋􀀑􀀇􀀈􀀛􀀋􀀅􀀏hy (T􀀁􀀁) 􀀞􀀈􀀍fi􀀋􀀙􀀐􀀑 􀀙􀀂􀀒􀀄􀀇􀀒􀀈􀀚􀀐􀀑 L􀀘􀀘 􀀅􀀍􀀅􀀄􀀈􀀙y 􀀇􀀍 􀀅􀀒􀀒 􀀞􀀅􀀃􀀐􀀃 . H􀀅􀀒f 􀀈f 􀀄h􀀐 􀀏􀀋􀀈􀀞􀀐􀀑􀀂􀀋􀀐􀀃 w􀀐􀀋􀀐 fl􀀂􀀈􀀋􀀈􀀃􀀞􀀈􀀏y􀀕􀀛􀀂􀀇􀀑􀀐􀀑 w􀀇􀀄h 􀀈􀀍􀀐 􀀑􀀐􀀒􀀇 􀀐􀀋y 􀀃h􀀐􀀅􀀄h 􀀅􀀍􀀑􀀄􀀋􀀅􀀍􀀃􀀃􀀐􀀏􀀄􀀅􀀒 􀀏􀀂􀀍􀀞􀀄􀀂􀀋􀀐􀀎 wh􀀇􀀒􀀐 􀀄h􀀐 􀀈􀀄h􀀐􀀋 h􀀅􀀒f w􀀐􀀋􀀐 T􀀁􀀁􀀕􀀛􀀂􀀇􀀑􀀐􀀑 w􀀇􀀄h 􀀅 􀀑􀀈􀀂􀀚􀀒􀀐􀀃h􀀐􀀅􀀄h 􀀅􀀍􀀑 􀀄w􀀈 􀀄􀀋􀀅􀀍􀀃􀀃􀀐􀀏􀀄􀀅􀀒 􀀏􀀂􀀍􀀞􀀄􀀂􀀋􀀐􀀃 . 􀀌􀀍􀀒y 􀀘􀀙􀀏􀀒􀀅􀀄􀀔􀀐􀀋 􀀑􀀐 􀀇􀀞􀀐􀀃 w􀀐􀀋􀀐 􀀂􀀃􀀐􀀑:􀀁􀀇􀀛h􀀄 􀀏􀀋􀀈􀀞􀀐􀀑􀀂􀀋􀀐􀀃 􀀐􀀙􀀏􀀒􀀈y􀀐􀀑 􀀄w􀀈 􀀑􀀐 􀀇􀀞􀀐􀀃 􀀈f 􀀄h􀀐 􀀃􀀅􀀙􀀐 􀀄y􀀏􀀐 [fi 􀀐 􀀘􀀙􀀂􀀒􀀐􀀄􀀎 􀀄h􀀋􀀐􀀐􀀘􀀙􀀏􀀒􀀅􀀄􀀔􀀐􀀋 C􀀅􀀋􀀑􀀇􀀅􀀞 P􀀒􀀂􀀛 (􀀘CP","cbCaitYaeRx71wdx","https://ap.wps.com/l/cbCaitYaeRx71wdx","pdf",1478246,11,"English","# Objectives\n# Methods\n# Results\n## Efficacy outcomes\n## Safety outcomes\n# Discussion\n## Limitations\n# Conclusions","[{\"question\":\"What is the study about?\",\"answer\":\"The study focuses on percutaneous left atrial appendage closure performed together with concomitant dual-device implantation at a single center.\"},{\"question\":\"How were outcomes evaluated?\",\"answer\":\"Outcomes were evaluated using reported objective endpoints and follow-up results, with statistical testing including significance thresholds and confidence intervals.\"},{\"question\":\"What types of results are presented?\",\"answer\":\"The document reports both efficacy-related outcomes and safety/complication-related findings, along with subgroup information such as age categories and patient characteristics.\"}]","Percutaneous left atrial appendage closure with concomitant dual-device implantation: a single-center | PDF",1790708317,28]