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Root canal treatment is common, but partial pulpotomy (PP) has shown strong potential for maintaining pulp vitality. This systematic review evaluates PP success in vital, mature permanent teeth with carious pulp exposure, with emphasis on adults aged 18+ where evidence remains limited. Outcomes are synthesized across follow-ups of at least one year.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/partial-pulpotomy-for-carious-pulp-exposure-in-adult-mature-permanent-teeth-a-systematic-review-and-meta-analysis/457668/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/partial-pulpotomy-for-carious-pulp-exposure-in-adult-mature-permanent-teeth-a-systematic-review-and-meta-analysis/457668.png","ImageObject",300,407,{"name":92,"@type":93},"SANS","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-06","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":81},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the main purpose of the systematic review?","Question",{"text":112,"@type":113},"To assess the success rates of partial pulpotomy for vital, adult mature permanent teeth with carious pulp exposure, focusing on adults aged 18 and older.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which studies and follow-up period were included?",{"text":117,"@type":113},"Randomized controlled trials and observational studies published from 2000 to 2025, with outcomes based on at least one year of follow-up.",{"name":119,"@type":110,"acceptedAnswer":120},"How did capping materials affect PP success rates?",{"text":121,"@type":113},"Calcium hydroxide showed a lower mean success rate (34.3%), while tri-calcium silicate materials such as MTA and Biodentine achieved higher success (86.8%), producing a large mean difference.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},457668,1790811629,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":81,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},962090760505,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Abdelkhader et al. BMCOral Health (2026) 26:31 BMC Oral Health  \n[https://doi.org/10.1186/s12903-025-07408-x](https://doi.org/10.1186/s12903-025-07408-x)  \nSYSTEMATIC REVIEW Open Access  \nPartial pulpotomy for carious pulp exposure in adult mature permanent teeth: a systematic review and meta-analysis  \nSakha Abdelkhader 1*, Garrit Koller 1, Jing Kang 1 and Francesco Mannocci 1*  \nAbstract  \nBackground Deep carious lesions often lead to pulp exposure, highlighting the need for effective pulp preservation strategies. While root canal treatment was the conventional approach, alternatives like partial pulpotomy (PP) showed high success rates in maintaining pulp vitality. This review aimed to assess the success rates of PP in vital, mature teeth with carious pulp exposure, particularly focusing on adults aged 18 and older, as recent research is limited.  \nMethods This systematic review (PROSPERO ID: CRD42024494545) examines the success rate of partial pulpotomyin adult mature permanent teeth with carious pulp exposure after at least one year of follow-up. The PICO framework outlines the population (adults with mature teeth), intervention (partial pulpotomy), comparators (various capping materials and pulp therapies), and outcome (success rates) . Databases used for research included PubMed, ScienceDirect, Cochrane Library, and Embase. Inclusion criteria focused on RCTs and observational studies from 2000 to 2025 involving adults with deep carious pulp exposure, while exclusion criteria eliminated animal studies, case reports, and studies on primary teeth. Quality assessment tools included the Cochrane RoB 2 tool for RCTs and the Newcastle-Ottawa Scale for observational studies. Mesh terms used included (“pulpotomy” OR “pulp therapy”) AND (“mature” OR “adults”) OR (“carious” OR“Pulp exposure”) .  \nResults The search yielded six randomized controlled trials reported in eight records and three observational studies from 42,320 records, highlighting significant success rate differences among capping materials. PP using Calcium hydroxide (CH) had a mean success rate of 34 . 3%(95% CI: [24 . 93%, 43 . 67%]), while tri-calcium silicate materials (MTA and Biodentine) achieved 86. 8%(95% CI: [83 . 78%, 89 . 82%]), resulting in a 52 . 5% mean difference. Timing of restoration also influenced outcomes: immediate restorations had a success rate of 89 . 9%, whereas delays reduced rates significantly. Meta-regression indicated tri-calcium silicate use increased success by 37%(P = 0 . 0002), while each day of delay decreased success by 0.088 (P = 0 . 023) . Further analysis found no significant difference between pulpotomy and full pulpotomy (pooled effect estimate: -0 . 77) CI: [-1 . 62 to 0 . 09] .  \nConclusion Partial pulpotomy (PP) is an effective treatment for carious pulp exposure in adults, with success largely dependent on the material used; tri-calcium silicate cements are preferred over calcium hydroxide.  \n*Correspondence:  \nSakha Abdelkhader [Sakha.abdel khader@kcl.ac.uk](Sakha.abdel khader@kcl.ac.uk)[ ](Sakha.abdel khader@kcl.ac.uk)Francesco Mannocci [Francesco.Mannocci@kcl.ac.uk](Francesco.Mannocci@kcl.ac.uk)  \nFull list of author information is available at the end of the article  \n© The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the articl","cbCaiuJL8WhGUMSE","https://ap.wps.com/l/cbCaiuJL8WhGUMSE","pdf",2235444,13,"English","# Abstract\n# Background\n# Methods\n# Results\n# Conclusion\n# Clinical implications","[{\"question\":\"What is the main purpose of the systematic review?\",\"answer\":\"To assess the success rates of partial pulpotomy for vital, adult mature permanent teeth with carious pulp exposure, focusing on adults aged 18 and older.\"},{\"question\":\"Which studies and follow-up period were included?\",\"answer\":\"Randomized controlled trials and observational studies published from 2000 to 2025, with outcomes based on at least one year of follow-up.\"},{\"question\":\"How did capping materials affect PP success rates?\",\"answer\":\"Calcium hydroxide showed a lower mean success rate (34.3%), while tri-calcium silicate materials such as MTA and Biodentine achieved higher success (86.8%), producing a large mean difference.\"}]","Partial pulpotomy for carious pulp exposure in adult mature permanent teeth - a systematic review and meta-analysis | PDF",1790750102,33]