[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-387336-105":59,"doc-detail-387336-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","parent-fact-sheet-argininosuccinic-acidemia-asa","Parent Fact Sheet - Argininosuccinic Acidemia (ASA)","","Parent-oriented fact sheet explaining argininosuccinic acidemia (ASA), a metabolic disorder caused by inability to process protein due to lack of the ASA lyase enzyme. It describes likely symptoms such as feeding refusal and vomiting, and outlines risks including seizures and coma without early diagnosis and treatment. It provides inheritance and recurrence probabilities for carrier parents and summarizes treatment options, including a low-protein diet, possible arginine supplementation, and liver transplant in some cases, plus guidance for locating care in Virginia.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/parent-fact-sheet-argininosuccinic-acidemia-asa/387336/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/parent-fact-sheet-argininosuccinic-acidemia-asa/387336.png","ImageObject",300,407,{"name":92,"@type":93},"Eliana","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is argininosuccinic acidemia (ASA) and what causes it?","Question",{"text":112,"@type":113},"ASA is a metabolic disorder where the body cannot process protein properly due to a lack of the argininosuccinic acid (ASA) lyase enzyme. This leads to buildup of ASA, citrulline, and ammonia in the blood.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What problems can happen if ASA is not treated?",{"text":117,"@type":113},"A baby may refuse to eat and have vomiting. If untreated, ASA can lead to seizures and coma, so early diagnosis and treatment help prevent these problems.",{"name":119,"@type":110,"acceptedAnswer":120},"If both parents are carriers, what are the chances for each pregnancy?",{"text":121,"@type":113},"For each pregnancy there is a 25% chance the baby will have ASA, a 50% chance the baby will be a carrier, and a 25% chance the baby will not have the condition and will not be a carrier.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},387336,1790944490,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":34,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":81,"preview_page_count":4},4398048949847,"https://ap-avatar.wpscdn.com/avatar/400002536579ef2da7f?_k=1778318612642679267","Parent Fact Sheet  \nArgininosuccinic Acidemia (ASA)  \n(Argin-in-o-suc-sin-ic A-sid-EE-mia)  \nWhat is ASA?  \nArgininosuccinic Acidemia (ASA) is a metabolic disorder. This means the body has a chemical imbalance. ASA is a condition in which the body is not able to process protein properly. People with this condition lack a certain enzyme. The enzyme is called argininosuccinic acid (ASA) lyase. The lack of this enzyme results in a build-up of chemicals in the blood. These chemicals include ASA, citrulline, and ammonia. ASA is inherited. This means it is present at birth.  \nWhat type of problems occurs with ASA?  \nA baby who has this condition may refuse to eat and have vomiting. If untreated, this condition can lead to seizures and coma. Early diagnosis and treatment will help prevent these problems.  \nWhat is the chance my baby will have ASA?  \nThis condition occurs in less than 1 in every 100,000 births. Babies born with this condition have a changed gene from each parent. A person who has one changed gene is called a carrier. A person who is a carrier does not have symptoms. If both parents are carriers, either parent can pass on the changed gene to their baby. If both parents pass on the changed gene, the baby will have the condition. If both parents are carriers, for each pregnancy:  \n􀁸 There is a 25% chance that the baby will be born with this condition. •  \n􀁸 There is a 50% chance that the baby will be a carrier for this condition.  \n􀁸 There is a 25% chance that the baby will not be born with this condition and will not be a carrier.  \nWhat is the treatment of ASA?  \nThe treatment for this condition is usually a low protein diet. A supplement called arginine might be needed. Your baby’s metabolic doctor will help you make sure that your baby gets the right diet and medical care. Routine illness, like the common cold, can make this condition worse. So be sure to contact your baby’s doctor whenever your baby gets sick. Sometimes a liver transplant is needed.  \nWhere in Virginia can I take my baby for care?  \nPlease speak to your baby’s pediatrician about obtaining a referral to a pediatric metabolic specialist in your area. If you want to know more about this condition, please contact Virginia Newborn Screening Services, Virginia Department of Health.. The Web site is [http://www.vahealth.org/gns](http://www.vahealth.org/gns).","cbCaieXPa2B5s1hI","https://ap.wps.com/l/cbCaieXPa2B5s1hI","pdf",218321,"English","# What is ASA?\n# What type of problems occurs with ASA?\n# What is the chance my baby will have ASA?\n# What is the treatment of ASA?\n# Where in Virginia can I take my baby for care?","[{\"question\":\"What is argininosuccinic acidemia (ASA) and what causes it?\",\"answer\":\"ASA is a metabolic disorder where the body cannot process protein properly due to a lack of the argininosuccinic acid (ASA) lyase enzyme. This leads to buildup of ASA, citrulline, and ammonia in the blood.\"},{\"question\":\"What problems can happen if ASA is not treated?\",\"answer\":\"A baby may refuse to eat and have vomiting. If untreated, ASA can lead to seizures and coma, so early diagnosis and treatment help prevent these problems.\"},{\"question\":\"If both parents are carriers, what are the chances for each pregnancy?\",\"answer\":\"For each pregnancy there is a 25% chance the baby will have ASA, a 50% chance the baby will be a carrier, and a 25% chance the baby will not have the condition and will not be a carrier.\"}]","Parent Fact Sheet - Argininosuccinic Acidemia (ASA) | PDF",1790285153]