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This pragmatic observational study compared the Papette brush against the traditional spatula with endocervical brush (cytobrush) for cervical cancer screening, analyzing pathology reports for satisfactory versus unsatisfactory results. Among 756 Pap tests, the Papette yielded satisfactory results in 93.8% versus 93.0% for cytobrush, supporting non-inferiority.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/papanicolaou-test-collection-with-the-papette-brush-or-the-spatula-with-cytobrush-a-pragmatic-study/375524/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/papanicolaou-test-collection-with-the-papette-brush-or-the-spatula-with-cytobrush-a-pragmatic-study/375524.png","ImageObject",300,407,{"name":92,"@type":93},"Patrick","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-28","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the objective of this pragmatic study?","Question",{"text":112,"@type":113},"To compare use of the Papette brush with the traditional spatula plus endocervical brush (cytobrush) for cervical cancer screening.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were participants and screening performed?",{"text":117,"@type":113},"Adult women aged 21–64 eligible for a Papanicolaou test at a Midwest Community Internal Medicine practice underwent screening using either Papette or spatula with cytobrush from 18 August 2021 through 1 February 2022.",{"name":119,"@type":110,"acceptedAnswer":120},"What did the results show about test adequacy?",{"text":121,"@type":113},"Papette produced satisfactory Pap test results 93.8% of the time versus 93.0% for the spatula with cytobrush.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},375524,1790401156,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":29,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},549758146520,"https://ap-avatar.wpscdn.com/avatar/80002397d8c0411e94?_k=1775819394049821470","Papanicolaou test collection with the Papette brush or the spatula with cytobrush: A pragmatic study  \nDanielle J O’Laughlin 1, Brittany A Strelow 1, Nicole A Fellows 1, Joy N Stevens 1, Elizabeth A Kelsey 1, Stephanie R Fink 1,  \nSonya M Peters 1, Jennifer A Johnson 1, Jaclyn P Houghton 1, Anne M Stolp 1, Karen M Fischer2, Johanna M Tweedy 1 and Ramona S DeJesus 1  \nWomen’s Health Volume 19: 1–6  \n© The Author(s) 2023  \nArticle reuse guidelines: [sagepub.com/journals-permissions](sagepub.com/journals-permissions)[ ](sagepub.com/journals-permissions)[DOI: 10.1177/17455057231170975](DOI: 10.1177/17455057231170975)[ ](DOI: 10.1177/17455057231170975)[journals.sagepub.com/home/whe](journals.sagepub.com/home/whe)  \nAbstract  \nBackground: Cotesting with the Papanicolaou (Pap) and human papillomavirus tests detects most precancerous and cancerous lesions and increases the sensitivity for detecting high-grade precancerous and invasive cervical cancers compared with human papillomavirus testing alone.  \nObjective: To compare the use of the Papette brush (hereafter Papette) to the traditional spatula with endocervical brush (cytobrush) for cervical cancer screening.  \nDesign: Pragmatic observational study.  \nMethods: Adult women aged 21–64 years who were eligible for a Papanicolaou test at a Midwest Community Internal Medicine practice underwent cervical cancer screening using the Papette or spatula with cytobrush from 18 August 2021 through 1 February 2022. Cluster sampling was used across the practice. Pathology reports were then analyzed to compare the number of satisfactory versus unsatisfactory results between the two collection techniques.  \nResults: We collected results for 756 Pap tests. The test results were satisfactory with the Papette 93.8% of the time compared with 93.0% for the spatula with cytobrush.  \nConclusion: The Papette is not inferior to a spatula with cytobrush as a collection method for Pap tests.  \nKeywords  \ncytobrush, Pap smear, Papanicolaou test, Papette, spatula  \nDate received: 10 October 2022; revised: 15 March 2023; accepted: 4 April 2023  \nIntroduction  \nIn 1940, cervical cancer was the leading cause of death for women of childbearing age.1 The development of the Papanicolaou (Pap) test by G. N. Papanicolaou in the late 1920s and publication of his landmark paper with H. Trautin 19412 led to widespread use of the Pap test in the 1950s, which dramatically reduced the incidence of cervical cancer deaths in the United States by more than 60% .1 Used to detect abnormal or atypical cervical cellular changes suggestive of an actual or precancerous lesion, the Pap test has remained a standard, routinely used tool for cervical cancer screening.  \nThe Pap test, which assesses cervical cytology on collected samples, can be performed alone or in combination with human papillomavirus (HPV) testing. HPV testing can also be performed alone (currently collected by a  \n1 Division of Community Internal Medicine, Mayo Clinic, Rochester, MN, USA  \n2Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN, USA  \nCorresponding author:  \nRamona S DeJesus, Division of Community Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.  \nEmail: [dejesus.ramona@mayo.edu](dejesus.ramona@mayo.edu)  \nCreative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License ([https://creativecommons.org/licenses/by-nc/4.0/](https://creativecommons.org/licenses/by-nc/4.0/)) which permits non-commercial use,  \nreproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages ([https://us.sagepub.com/en-us/nam/open-access-at-sage](https://us.sagepub.com/en-us/nam/open-access-at-sage)).  \npractitioner), is now an accepted screening test for cervical cancer for average-risk women aged 30 or older, and has the potential for future self-col","cbCaiaPOsayD1BNt","https://ap.wps.com/l/cbCaiaPOsayD1BNt","pdf",848879,"English","# Abstract\n## Background\n## Objective\n## Design\n## Methods\n## Results\n## Conclusion\n# Introduction\n# Methods and Procedures","[{\"question\":\"What was the objective of this pragmatic study?\",\"answer\":\"To compare use of the Papette brush with the traditional spatula plus endocervical brush (cytobrush) for cervical cancer screening.\"},{\"question\":\"How were participants and screening performed?\",\"answer\":\"Adult women aged 21–64 eligible for a Papanicolaou test at a Midwest Community Internal Medicine practice underwent screening using either Papette or spatula with cytobrush from 18 August 2021 through 1 February 2022.\"},{\"question\":\"What did the results show about test adequacy?\",\"answer\":\"Papette produced satisfactory Pap test results 93.8% of the time versus 93.0% for the spatula with cytobrush.\"}]","Papanicolaou test collection with the Papette brush or the spatula with cytobrush - A pragmatic study | PDF",1790215244,15]