[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-343499-105":59,"doc-detail-343499-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","pancreatic-ductal-adenocarcinoma-staging-a-narrative-review-of-radiologic-techniques-and-advances","Pancreatic ductal adenocarcinoma staging - a narrative review of radiologic techniques and advances","","Radiology plays a crucial role in diagnosing and staging pancreatic ductal adenocarcinoma (PDAC), with CT typically preferred over MRI because of broader availability, more consistent image quality, and lower cost. MRI and PET/CT are used selectively as problem-solving tools. National Comprehensive Cancer Network (NCCN) criteria guide resectability triage based on vascular involvement, while restaging after neoadjuvant therapy depends on imaging accuracy and radiologist experience. Challenges include predicting nodal spread and detecting subtle liver or peritoneal metastases. Artificial intelligence may improve small early tumor detection and generate imaging biomarkers for recurrence and survival, supporting better surgery selection and outcomes.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/pancreatic-ductal-adenocarcinoma-staging-a-narrative-review-of-radiologic-techniques-and-advances/343499/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/pancreatic-ductal-adenocarcinoma-staging-a-narrative-review-of-radiologic-techniques-and-advances/343499.png","ImageObject",300,407,{"name":92,"@type":93},"River Wang","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-22",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why is CT typically preferred over MRI for PDAC staging?","Question",{"text":112,"@type":113},"CT is preferred due to wider availability, more consistent image quality, and lower cost.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How do NCCN guidelines categorize PDAC resectability?",{"text":117,"@type":113},"They define resectability categories based on tumor involvement of arteries and veins, triaging patients into resectable, borderline resectable, locally advanced, and metastatic groups.",{"name":119,"@type":110,"acceptedAnswer":120},"What challenges complicate accurate preoperative staging in PDAC?",{"text":121,"@type":113},"Key challenges include predicting lymph node metastases, detecting subtle liver and peritoneal metastases, and performing accurate disease restaging after neoadjuvant therapy.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},343499,1790169912,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":41},1099514067438,"https://ap-avatar.wpscdn.com/avatar/100002539ee87300030?x-image-process=image/resize,m_fixed,w_180,h_180&k=1780474512215547542","’Invited Special Paper   \nPancreatic ductal adenocarcinoma staging: a narrative review of radiologic techniques and advances  \nLinda C. Chu, MD* , Elliot K. Fishman, MD  \nAbstract   \nRadiology plays an important role in the initial diagnosis and staging of patients with pancreatic ductal adenocarcinoma (PDAC) . CTis the preferred modality over MRI due to wider availability, greater consistency in image quality, and lower cost. MRI and PET/CT are usually reserved as problem-solving tools in select patients. The National Comprehensive Cancer Network (NCCN) guidelines define resectability criteria based on tumor involvement of the arteries and veins and triage patients into resectable, borderline resectable, locally advanced, and metastatic categories. Patients with resectable disease are eligible for upfront surgical resection, while patients with high-stage disease are treated with neoadjuvant chemotherapy and/or radiation therapy with hopes of downstaging the disease. The accuracy of staging critically depends on the imaging technique and the experience of the radiologists. Several challenges in accurate preoperative staging include prediction of lymph node metastases, detection of subtle liver and peritoneal metastases, and disease restaging following neoadjuvant therapy. Artificial intelligence (AI) has the potential to function as ‘second readers’ to improve upon the radiologists ’ detection of small early-stage tumors, which can shift more patients toward surgical resection of potentially curable cancer. AI may also provide imaging biomarkers that can predict disease recurrence and patient survival after pancreatic resection and assist in the selection of patients most likely to benefit from surgery, thus improving patient outcomes.  \nKeywords: artificial intelligence, cinematic rendering, computed tomography, magnetic resonance imaging, pancreatic cancer, radiology, radiomics  \nIntroduction  \nPancreatic ductal adenocarcinoma (PDAC) is the seventh leading cause of cancer mortality worldwide based on GLOBOCAN 2020 estimates, and over 466 000 patients with pancreatic cancer succumbed to the disease in 2020 [1] . The age-standardized incidence of PDAC is fourfold to fivefold higher in countries with a high development index, with the greatest incidence in Europe, North America, Australia, and  \nThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA  \nSponsorships or competing interests that maybe relevant to content are disclosed atthe end of this article.  \n*Corresponding author. Address: Hal B168, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, Maryland 21287, USA. Tel.: +1 410 955 9446;  \nfax: +1 410 578 2862. E-mail: [lindachu@jhmi.edu](lindachu@jhmi.edu) (L.C. Chu).  \nCopyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.  \nInternational Journal of Surgery (2024) 110:6052–6063  \nReceived 9 June 2023; Accepted 2 November 2023  \nSupplemental Digital Content is available for this article. Direct URL citations are provided in the HTML and PDF versions of this article on the journal’s website, [www.lww.com/international-journal-of-surgery](www.lww.com/international-journal-of-surgery).  \nPublished online 4 December 2023  \n[http://dx.doi.org/10.1097/JS9.0000000000000899](http://dx.doi.org/10.1097/JS9.0000000000000899)  \nHIGHLIGHTS  \n• Radiology plays an important role in the initial diagnosis and staging of pancreatic cancer.  \n• CT is the preferred modality over MRI due to wider availability, greater consistency in image quality, and lower cost.  \n• Patients can be triaged into resectable, ","cbCainfWsxflgfmp","https://ap.wps.com/l/cbCainfWsxflgfmp","pdf",1312696,12,"English","# Abstract\n# Introduction\n# Role of radiology in cancer detection","[{\"question\":\"Why is CT typically preferred over MRI for PDAC staging?\",\"answer\":\"CT is preferred due to wider availability, more consistent image quality, and lower cost.\"},{\"question\":\"How do NCCN guidelines categorize PDAC resectability?\",\"answer\":\"They define resectability categories based on tumor involvement of arteries and veins, triaging patients into resectable, borderline resectable, locally advanced, and metastatic groups.\"},{\"question\":\"What challenges complicate accurate preoperative staging in PDAC?\",\"answer\":\"Key challenges include predicting lymph node metastases, detecting subtle liver and peritoneal metastases, and performing accurate disease restaging after neoadjuvant therapy.\"}]","Pancreatic ductal adenocarcinoma staging - a narrative review of radiologic techniques and advances | PDF",1790051318]