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Surgical resection remains the standard for high-risk PCNs, whereas low-risk PCNs are monitored with imaging to reduce the non-trivial likelihood of postoperative complications. Endoscopic ultrasound (EUS)-guided therapies, including injection and radiofrequency ablation, may provide a minimally invasive option for patients unfit for surgery, though their effect on mortality is still uncertain.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/pancreatic-club-perspectives-on-surgical-approach-post-resection-follow-up-and-role-of-endoscopic-ablation-on-pancreatic-cystic-neoplasms/373763/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/pancreatic-club-perspectives-on-surgical-approach-post-resection-follow-up-and-role-of-endoscopic-ablation-on-pancreatic-cystic-neoplasms/373763.png","ImageObject",300,407,{"name":92,"@type":93},"Mary Man","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",13,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why must pancreatic cystic neoplasms (PCNs) be managed using clinical and morphological criteria?","Question",{"text":113,"@type":114},"PCNs have malignant potential, so stratification by clinical and morphological features helps enable appropriate cancer prevention while avoiding overtreatment and unnecessary procedures.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What is the recommended approach for high-risk versus low-risk PCNs?",{"text":118,"@type":114},"High-risk PCNs should be treated with surgical resection, while low-risk PCNs should be monitored through imaging to mitigate the risk of postoperative complications.",{"name":120,"@type":111,"acceptedAnswer":121},"How do EUS-guided endoscopic therapies fit into the treatment strategy?",{"text":122,"@type":114},"EUS-guided ablation therapies such as injection or radiofrequency may offer minimally invasive treatment for patients not suitable for surgery, but their impact on prognostic outcomes like mortality remains uncertain.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},373763,1790240762,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":41},7421720224475,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","GE – Portuguese Journal of Gastroenterology  \nReview Article  \nGE Port J Gastroenterol DOI: 10. 1159/000548201  \nReceived: March 29, 2025  \nAccepted: July 7, 2025  \nPublished online: August 28, 2025  \nPancreatic Club Perspectives on Surgical Approach, Post-Resection Follow-Up, and Role of Endoscopic Ablation on Pancreatic Cystic Neoplasms  \nMiguel Martinsa, b Carlota Branco c Miguel Bispod Alexandra Fernandes e Eduardo Rodrigues-Pintoa, b Tiago Cúrdia Gonçalvesf, g, h  \nFilipe Vilas-Boasa, b Jorge Paulino c  \nOn behalf of the Portuguese Pancreatic Club  \nspecialized section of the Portuguese Society of Gastroenterology aGastroenterology Department, Centro Hospitalar Universitário de São João, Porto, Portugal; bFaculty of Medicine of the University of Porto, Porto, Portugal; cLuz Hospital Lisboa, Lisbon, Portugal; dDigestive Oncology  \nUnit, Champalimaud Foundation, Lisbon, Portugal; eGastroenterology Department, Centro Hospitalar de Leiria, Leiria, Portugal; fGastroenterology Department, Unidade Local de Saúde do Alto Ave – Hospital de Guimarães, Guimaraes, Portugal; gSchool of Medicine, University of Minho, Braga, Portugal; hICVS/3B’s–PT Government Associate Laboratory, Braga, Portugal  \nKeywords  \nPancreatic cyst neoplasms · Intraductal papillary mucinous neoplasm · Pancreatic surgery · Endosonography · Endoscopic ablation · Postoperative follow-up  \nAbstract  \nBackground: Pancreatic cystic neoplasms (PCNs) are lesions with malignant potential that should be addressed differently according to clinical/morphological criteria, to ensure appropriate cancer prevention and while avoiding overtreatment. Summary: Surgical resection remains the gold standard for high-risk PCNs (at least one high-risk stigmata, multiple “worrisome” features), whereas low-risk PCNs should be monitored through imaging to mitigate the non-negligible risk of postoperative complications. Endoscopic ultrasound (EUS)-guided therapies, such as  \ninjection or radiofrequency, may offer a minimally invasive and effective therapeutic option particularly for patients unfit for surgery, although their impact on prognostic (i.e., mortality) remains uncertain. Key Messages: This review summarizes the latest recommendations on surgical management and post-resection follow-up of PCNs and the potential role of EUS ablationin the treatment algorithm. © 2025 The Author(s) .  \nPublished by S. Karger AG, Basel  \nMiguel Martins and Carlota Branco share co-first authorship.  \n[karger@karger.com](karger@karger.com)[ ](karger@karger.com)[www.karger.com/pjg](www.karger.com/pjg)  \n© 2025 The Author(s) .  \nPublished by S. Karger AG, Basel  \nThis article is licensed under the Creative Commons AttributionNonCommercial 4.0 International License (CC BY-NC) ([https://](https://)[ ](https://)[karger.com/Services/OpenAccessLicense](karger.com/Services/OpenAccessLicense)). Usage and distribution for commercial purposes requires written permission.  \nPerspetiva do Clube Português do Pâncreas sobre aabordagem cirúrgica, o seguimento pós-ressecção epapel da ablação endoscópica das neoplasia císticaspancreáticas  \nPalavras Chave  \nNeoplasias císticas pancreáticas · Neoplasia mucinosaspapilar intraductal · Cirurgia pancreática · Ecoendoscopia · Ablação endoscópica · Seguimento pós-operatório  \nResumo  \nIntrodução: As neoplasias císticas pancreáticas (NCPs) são lesões com potential maligno e devem ser estratificadas de acordo com critérios clínicos/morfológicos, deforma a assegurar um equilíbrio entre a progressão para cancro e evitar intervenções desnecessárias. Sumário: Otratamento cirúrgico é a atitude de primeira linha para NCPs de alto risco (pelo menos 1 estigma de alto risco, múltiplas características preocupantes), enquanto os NCPs de baixo risco devem ser vigiados imagiologicamente para mitigar o risco não-negligenciável decomplicações pós-operatórias. As terapêuticas guiadaspor ultrassonografia endoscópica, como a ablação e radiofrequência, podem ser opções terapêuticas minimamente i","cbCaiiZxAiNqbiLC","https://ap.wps.com/l/cbCaiiZxAiNqbiLC","pdf",2286576,12,"English","# Abstract\n## Background\n## Summary\n## Key Messages\n# Introduction","[{\"question\":\"Why must pancreatic cystic neoplasms (PCNs) be managed using clinical and morphological criteria?\",\"answer\":\"PCNs have malignant potential, so stratification by clinical and morphological features helps enable appropriate cancer prevention while avoiding overtreatment and unnecessary procedures.\"},{\"question\":\"What is the recommended approach for high-risk versus low-risk PCNs?\",\"answer\":\"High-risk PCNs should be treated with surgical resection, while low-risk PCNs should be monitored through imaging to mitigate the risk of postoperative complications.\"},{\"question\":\"How do EUS-guided endoscopic therapies fit into the treatment strategy?\",\"answer\":\"EUS-guided ablation therapies such as injection or radiofrequency may offer minimally invasive treatment for patients not suitable for surgery, but their impact on prognostic outcomes like mortality remains uncertain.\"}]","Pancreatic Club Perspectives on Surgical Approach, Post-Resection Follow-Up, and Role of Endoscopic Ablation on Pancreatic Cystic Neoplasms | PDF",1790200392]