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Methods: An OPAT protocol was developed to enable safe outpatient FMT, guided by forthcoming national OPAT directives. Baseline review (2022–23) identified eligible patients and process mapping highlighted avoidable inpatient stays, coordinator dependence, and documentation burden. Results: In year one, four procedures met eligibility criteria, completed within 18 days of referral, and showed no recurrences; feedback was strongly positive and iterative staffing workflow changes were implemented. Challenges included costs, reimbursement, side-room capacity, and throughput.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/p09-broadening-horizons-the-use-of-opat-to-facilitate-outpatient-faecal-transplants/438617/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/p09-broadening-horizons-the-use-of-opat-to-facilitate-outpatient-faecal-transplants/438617.png","ImageObject",300,407,{"name":92,"@type":93},"Lucas Martin","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-09-30","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":8},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What problem does the OPAT protocol aim to solve for faecal microbiota transplantation (FMT)?","Question",{"text":112,"@type":113},"Standard FMT for Clostridioides difficile infection often requires inpatient admission and nasogastric tube delivery. The OPAT protocol was designed to support safe, effective outpatient administration instead.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What were the main findings after implementing outpatient FMT in the first year?",{"text":117,"@type":113},"Four FMT procedures were performed. All patients met national eligibility criteria, treatment occurred within 18 days of referral, and there were no recurrences of C. difficile infection; patient feedback was very positive.",{"name":119,"@type":110,"acceptedAnswer":120},"Which operational and financial factors constrained the outpatient FMT service?",{"text":121,"@type":113},"Procedure costs exceeded £1000, while outpatient reimbursement was lower than the procedure cost. Limited side-room availability also forced cancellation of PICC insertion slots, reducing throughput.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},438617,1790792570,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":8,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":14,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":24},8796095360427,"https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d","Posters  \nAbstract citation ID: dlaf239.013  \nP09 Broadening horizons: the use of OPAT to facilitate outpatient faecal transplants  \nThomas Harrison1, Clare Shaw1, Beatrix Teo1, Laura Prtak1, Katharine Cartwright1 1Sheffield Teaching Hospital, Sheffield, UK  \nBackground: Faecal microbiota transplantation (FMT) is a highly effective treatment for Clostridioides difficile infection and is typically administered via a nasogastric tube requiring inpatient admission. In line with forthcoming national OPAT guidelines promoting diversification of services beyond antimicrobial delivery, an OPAT protocol was developed and implemented to support safe and effective outpatient administration of FMT.  \nMethods: Baseline review ofCDI cases in the year 2022–23 identified 15 of 37 (40%) patients meeting FMT inclusion criteria; only four had a documented discussion and one received treatment. Among patients treated with FMT over the past decade, 10 of 12 (83%) met OPAT eligibility. Process mapping highlighted unnecessary inpatient  \nPosters  \nstays, over-dependence on a single coordinator, and the high burden of clerking and post-take documentation. A multidisciplinary team subsequently developed and implemented a pilot protocol for OPAT FMT delivery based on national guidance. Results: During the first year of implementation, four FMT procedures were performed. All patients met national eligibility criteria and underwent treatment within 18 days of referral, with no recurrences of C. difficile infection. Patient feedback questionnaire was very positive. Formal staff feedback after the first two proceduresidentified areas for improvement, including assigning a dedicated nurse to coordinate the FMT, having the referring clinician complete request forms for FMT material, reserving a doctor’s slot for consent, and clarifying reception booking processes. These modifications were applied to subsequent procedures.  \nChallenges and lessons learned: Implementation of outpatient FMT has been constrained by several operational andfinancial factors. The cost ofthe procedure exceeds £1000, while reimbursement for outpatient delivery is lower than the procedure cost, in contrast to inpatient admission where reimbursement is higher. Asa result, the department currently operates at a financial deficit, limiting the number of procedures that can be offered annually. The limited availability of side rooms necessitates cancellation of PICC insertion slots to accommodate FMT procedures, reducing overall throughput. Expanding the service to accept referrals from general practitioners and other hospitals that do not currently perform FMT could increase patient access while supporting continued development ofstaffexpertise. Future updates to national FMT protocols, including the potential use of oral FMT capsules, may eliminate the need for nasogastric administration and further facilitate outpatient delivery.  \nConclusions: Outpatient FMT via an OPAT pathway is feasible, safe, and wellreceived, aligning with the national drive for service diversification and demonstrating positive patient outcomes.","cbCaiaHpS7sCb88I","https://ap.wps.com/l/cbCaiaHpS7sCb88I","pdf",60854,"English","# Background\n# Methods\n# Results\n# Challenges and lessons learned\n# Conclusions","[{\"question\":\"What problem does the OPAT protocol aim to solve for faecal microbiota transplantation (FMT)?\",\"answer\":\"Standard FMT for Clostridioides difficile infection often requires inpatient admission and nasogastric tube delivery. The OPAT protocol was designed to support safe, effective outpatient administration instead.\"},{\"question\":\"What were the main findings after implementing outpatient FMT in the first year?\",\"answer\":\"Four FMT procedures were performed. All patients met national eligibility criteria, treatment occurred within 18 days of referral, and there were no recurrences of C. difficile infection; patient feedback was very positive.\"},{\"question\":\"Which operational and financial factors constrained the outpatient FMT service?\",\"answer\":\"Procedure costs exceeded £1000, while outpatient reimbursement was lower than the procedure cost. Limited side-room availability also forced cancellation of PICC insertion slots, reducing throughput.\"}]","P09 Broadening horizons - the use of OPAT to facilitate outpatient faecal transplants | PDF",1790685896]