[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-207477-105":3,"detail-sidebar-cat-0-en-105":74,"doc-detail-207477-en":124},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":67,"head_meta":69,"extra_data":71,"updated_unix":73},105,"en","oxford-cambridge-and-rsa-gcse-91-combined-science-b-twenty-first-century-science-j26001-biology-foundation-tier-sample-question-paper","Oxford Cambridge and RSA GCSE (9–1) Combined Science B (Twenty First Century Science) J260/01 Biology - Foundation Tier - Sample Question Paper","","This sample question paper for GCSE (9–1) Combined Science B (Twenty First Century Science) assesses foundation tier Biology knowledge across multiple genetics, cells and disease contexts. It includes tasks using key genetic terms, understanding mitochondrial inheritance and mitochondrial disease in a family scenario, and applying new-life-technology ethics and benefits. Other questions cover plant and animal pathogens, body defences, and interpreting Ebola signs, spread pathways, and transmission compared with a common infection.",{"@graph":14,"@context":66},[15,34,49],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/exam/","Exam",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/oxford-cambridge-and-rsa-gcse-91-combined-science-b-twenty-first-century-science-j26001-biology-foundation-tier-sample-question-paper/207477/",4,{"url":32,"name":10,"@type":35,"author":36,"headline":10,"publisher":39,"fileFormat":42,"inLanguage":8,"description":12,"dateModified":43,"datePublished":43,"encodingFormat":42,"isAccessibleForFree":44,"interactionStatistic":45},"DigitalDocument",{"name":37,"@type":38},"Lute","Person",{"url":19,"name":40,"@type":41},"DocShare","Organization","application/pdf","2026-09-05",true,{"@type":46,"interactionType":47,"userInteractionCount":4},"InteractionCounter",{"@type":48},"ViewAction",{"@type":50,"mainEntity":51},"FAQPage",[52,58,62],{"name":53,"@type":54,"acceptedAnswer":55},"What exam skills does this Biology foundation tier paper test?","Question",{"text":56,"@type":57},"It tests understanding of key genetics terms, mitochondrial inheritance, disease transmission prevention and benefits, and knowledge of pathogens, body defences, and infectious disease spread through scenario and data questions.","Answer",{"name":59,"@type":54,"acceptedAnswer":60},"How are marks for questions presented in the paper?",{"text":61,"@type":57},"The paper states that the total mark is 95 and that marks for each question are shown in brackets [ ]. Quality of extended response is assessed for the question marked with an asterisk (*).",{"name":63,"@type":54,"acceptedAnswer":64},"What does the paper ask about Ebola specifically?",{"text":65,"@type":57},"It asks for signs of Ebola from the article, an explanation of how Ebola spreads from person to person, and a description of how a common infection studied is spread from person to person.","https://schema.org",{"og:url":32,"og:type":68,"og:title":10,"og:site_name":40,"og:description":12},"article",{"robots":70,"canonical":32},"index,follow",{"doc_id":72,"site_id":7},207477,1788599737,{"code":4,"msg":75,"data":76},"success",[77,81,85,88,93,98,103,108,113,116,120],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":78,"show_sort_weight":79,"slug":80},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":82,"show_sort_weight":83,"slug":84},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":86,"slug":87},70,"exam",{"id":89,"doc_module":4,"doc_module_name":25,"category_name":90,"show_sort_weight":91,"slug":92},5,"Comic",60,"comic",{"id":94,"doc_module":4,"doc_module_name":25,"category_name":95,"show_sort_weight":96,"slug":97},6,"Technology",50,"technology",{"id":99,"doc_module":4,"doc_module_name":25,"category_name":100,"show_sort_weight":101,"slug":102},7,"Healthcare",40,"healthcare",{"id":104,"doc_module":4,"doc_module_name":25,"category_name":105,"show_sort_weight":106,"slug":107},8,"Research & Report",30,"research-report",{"id":109,"doc_module":4,"doc_module_name":25,"category_name":110,"show_sort_weight":111,"slug":112},9,"Religion & Spirituality",20,"religion-spirituality",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":114,"show_sort_weight":111,"slug":115},"World Cup","world-cup",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":118,"show_sort_weight":117,"slug":119},10,"Lifestyle","lifestyle",{"id":121,"doc_module":4,"doc_module_name":25,"category_name":122,"show_sort_weight":89,"slug":123},19,"General","general",{"code":4,"msg":75,"data":125},{"doc_id":72,"user_id":126,"nickname":37,"user_avatar":127,"doc_module":4,"category_id":33,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":128,"file_id":129,"file_url":130,"file_type":131,"file_size":132,"view_count":4,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":91,"language":133,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":134,"faqs":135,"seo_title":136,"seo_description":12,"update_tm":73,"read_time":137},137454149569,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","* 0 0 0 0 0 0 0 0 0 0 *  \nOxford Cambridge and RSA  \nGCSE (9–1) Combined Science B (Twenty First Century Science) J260/01 Biology (Foundation Tier)  \nSample Question Paper  \nF  \nDate – Morning/Afternoon Version 2.2  \nTime allowed: 1 hour 45 minutes  \n* 0 0 0 0 0 0 *  \nYou may use:  \n• a scientific or graphical calculator  \n\n| First name |  |  |  |  |  |  |  |  |  |  |  |\n| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |\n| Last name |  |  |  |  |  |  |  |  |  |  |  |\n| Centre number |  |  |  |  | |  | Candidate number |  |  |  |  |\n\nINSTRUCTIONS  \n• Use black ink. HB pencil may be used for graphs and diagrams only.  \n• Complete the boxes above with your name, centre number and candidate number.  \n• Answer all the questions.  \n• Write your answer to each question in the space provided.  \n• Additional paper may be used if required but you must clearly show your candidate number, centre number and question number(s) .  \n• Do not write in the bar codes.  \nINFORMATION  \n• The total mark for this paper is 95.  \n• The marks for each question are shown in brackets [ ] .  \n• Quality of extended response will be assessed in the question marked with an asterisk (*) .  \n• This document consists of 32 pages.  \n© OCR 2021 J260/01  \n[601/8690/2] D10046/2 .2 Turn over  \nAnswer all the questions.  \n1 (a) Scientists use key terms to explain genetics.  \nUse words from the list to complete the sentences about genetics.  \nYou may use each word, once, more than once or not at all.  \nalleles chromosomes genes genome nucleotides  \nThe molecule which carries the genetic information is DNA. DNA is a polymer made up of……………………  \nSections of DNA which code for a particular protein are called ……………………  \n[2]  \n(b) Mitochondria are sub-cellular structures inside nearly every cell of the  \nbody. They have a small amount of their own DNA.  \nMitochondria are inherited only from the mother. Mitochondria are inherited in the cytoplasm of the egg.  \nSome faulty mitochondria cause Mitochondrial Disease (MD) . Symptoms can be brain damage, muscle wasting, heart failure and blindness.  \nLook at the family tree. Mia has Mitochondrial Disease (MD) .  \nName the four other people in Mia’s family tree who will definitely have Mitochondrial Disease.  \n1......................... 2......................... 3......................... 4......................... [2]  \n(c) (i) In February 2015 the UK became the first country in the world to approve laws to allow the creation of babies with genetic material from three people.  \nThe new laws were passed to help develop treatments for Mitochondrial Disease.  \nThe diagram shows one way in which passing on Mitochondrial Disease might be prevented.  \nExplain why the embryo at the end of the process can be described as having three parents.  \n........................................................................................................................  \n.................................................................................................................. [2]  \n(ii) State two possible benefits of this new technique.  \nInclude practical and ethical considerations.  \n1 ......................................................................................................................  \n........................................................................................................................  \n2 ........................................................................................................................................................................................................................................ [2]  \n2 (a) Communicable diseases in plants and animals can be caused by  \nmicroorganisms called pathogens.  \nPut a tick (✓) in the box next to the type of organism that does not cause infectious disease.  \nType of organism  \nBacteria  \nFungi  \nInsects  \nProtists [1]  \n(b) Our bodies have defences that make it difficult for pathogens to enter.  \nUse lines to ","cbCaieIIJthyNmkG","https://ap.wps.com/l/cbCaieIIJthyNmkG","pdf",2108704,"English","# Instructions and information\n## Question marks and assessment\n# Genetics and inheritance\n## Key terms for genetics and DNA\n## Mitochondrial inheritance and disease in a family tree\n## Preventing transmission and describing three parents\n## Benefits with practical and ethical considerations\n# Pathogens and human defences\n## Non-infectious organism selection\n## Linking defences to descriptions\n# Ebola and infectious disease\n## Identifying signs of infection\n## Explaining person-to-person spread\n## Comparing with another common infection","[{\"question\":\"What exam skills does this Biology foundation tier paper test?\",\"answer\":\"It tests understanding of key genetics terms, mitochondrial inheritance, disease transmission prevention and benefits, and knowledge of pathogens, body defences, and infectious disease spread through scenario and data questions.\"},{\"question\":\"How are marks for questions presented in the paper?\",\"answer\":\"The paper states that the total mark is 95 and that marks for each question are shown in brackets [ ]. Quality of extended response is assessed for the question marked with an asterisk (*).\"},{\"question\":\"What does the paper ask about Ebola specifically?\",\"answer\":\"It asks for signs of Ebola from the article, an explanation of how Ebola spreads from person to person, and a description of how a common infection studied is spread from person to person.\"}]","Oxford Cambridge and RSA GCSE (9–1) Combined Science B (Twenty First Century Science) J260/01 Biology - Foundation Tier - Sample Question Paper | PDF",151]