[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-213119-en":3,"doc-seo-213119-105":31,"detail-sidebar-cat-0-en-105":92},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":20,"is_deleted":4,"is_public":21,"is_downloadable":21,"audit_status":21,"page_count":22,"language":23,"language_code":24,"site_id":25,"html_lang":24,"table_of_contents":26,"faqs":27,"seo_title":28,"seo_description":14,"update_tm":29,"read_time":30},213119,1649267921044,"Ava Thompson","https://us-avatar.wpscdn.com/avatar/1800007509477c92dfb?_k=1786009248482753345",7,"Healthcare","Overactive Bladder and Urge Urinary Incontinence (OAB & UUI) - Outline","Overactive bladder and urge urinary incontinence (OAB & UUI) are presented through clear definitions of key symptom terms: urinary urgency, urge incontinence, nocturia, nocturnal polyuria, and frequency. The material summarizes prevalence by sex and age using major survey references, including global estimates, unmet treatment needs, and Taiwan-specific rates. It also explains the pathophysiology from myogenic and neurogenic mechanisms, listing potential etiologies such as aging, neurologic and cerebrovascular diseases, spinal injury, pelvic floor disorders, and bladder-related comorbidities.","Overactive Bladder and Urge Urinary incontinence (OAB & UUI)  \n泌尿科吳書雨醫師  \nOutline  \n• Definition and terminology  \n• Prevalence  \n• Pathophysiology  \n• Diagnosis  \n• Treatments  \nDefinition & Terminology  \n• Overactive bladder  \n• A symptom syndrome  \n• Urinary urgency, with or without urge incontinence, usually accompanied by frequency and nocturia  \n• No signs of other pathology or infection  \n• Urgency  \n• The complaint of a sudden compelling desire to pass urine, which is difficult to defer  \n• Urge urinary incontinence  \n• The complaint of involuntary loss of urine accompanied by or immediately preceding by urgency  \nDefinition & Terminology  \n• Nocturia  \n• Walking to pass urine during the main sleep period  \n• The first nocturia episode must be preceded by sleep  \n• Nocturia once was thought to be normal  \n• Nocturnal polyuria  \n• More than 33% of the total daily urine output occurs at night (or sleep)  \n• Frequency  \n• Average voiding times: 8/day  \n• Many times in a short time  \nPreva lence (%)  \nPrevalence  \n40  \n35  \n30  \n25  \n20  \n15  \n10  \n5  \n0  \nMen (SIFO 1997) Women (SIFO 1997) Men (EPIC 2005) Women ( EPIC 2005)  \n 16.6 %  \n 11.8 %  \n18-29 30-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 > 70  \nSIFO: Sifo/Gallup telephone survey  \n* N = 16,776 interviews (6 European countries)  \n† N = 19,165 interviews (4 European countries and Canada)  \nAge (years)  \nPrevalence  \n• Up to 100 million worldwide  \n• 16.6% of adult population in US  \n• OAB dry: 13.6% men, 7.6% women  \n• OAB wet: 2.4% men, 9.3% women  \n• \u003C40% seek treatment  \n• In Taiwan  \n• 16.9% of adult population  \n• 30~79 y/o: 18.2%  \n• OAB dry: 13.7%  \n• OAB wet: 4.5%  \nImpact of incontinence  \n• Quality of life  \n• Associated with depression and anxiety, work impairment, and social isolation  \n• Sexual dysfunction  \n• 30%(fear of) coital incontinence  \n• Morbidity  \n• Perineal infections  \n• Falls and fractures  \n• Caregiver burden  \n• 6-10% of nursing home admissions  \nPathophysiology  \n• Myogenic  \n• Alterations in structural and functional properties of the detrusor muscle  \n• Partial denervation of the detrusor muscle  \n• Supersensitivity to acetylcholine (ACh)  \n• Abnormal spontaneous mechanical activity  \n• Neurogenic  \n• Increased afferent activity  \n• Decreased central inhibitory control  \n• Increased detrusor sensitivity to motor input  \nPathophysiology  \n• Possible causes  \n• Aging  \n• Idiopathic  \n• Cerebrovascular disease  \n• Stroke, Alzheimer disease, multi-infarct or other dementias, Parkinson disease, or multiple sclerosis  \n• Spinal cord injury or spine surgery  \n• Metabolic, degenerative, or neurogenic diseases  \n• Disorders of the PFM(POP, fecal incontinence)  \n• Abdominal or pelvic operation  \n• Bladder outlet obstruction  \n• Depression or anxiety  \nPathophysiology","cbCaisGMrw1XyIvY","https://ap.wps.com/l/cbCaisGMrw1XyIvY","pdf",2131614,2,1,37,"English","en",105,"# Outline\n## Definition and terminology\n## Prevalence\n## Impact of incontinence\n## Pathophysiology","[{\"question\":\"How are overactive bladder and urge urinary incontinence defined in this outline?\",\"answer\":\"Overactive bladder is described as a symptom syndrome featuring urinary urgency, with or without urge incontinence, usually accompanied by frequency and nocturia. Urge urinary incontinence is involuntary urine loss that is accompanied by or immediately preceded by urgency.\"},{\"question\":\"What causes nocturia in the context of OAB \\u0026 UUI?\",\"answer\":\"Nocturia is defined as walking to pass urine during the main sleep period, with the first episode occurring after sleep. Nocturnal polyuria is noted when more than 33% of total daily urine output occurs at night or during sleep.\"},{\"question\":\"What pathophysiological mechanisms are discussed for OAB \\u0026 UUI?\",\"answer\":\"The outline covers myogenic mechanisms, including detrusor muscle structural/functional alterations, partial denervation, and supersensitivity to acetylcholine with abnormal spontaneous activity. It also describes neurogenic mechanisms such as increased afferent activity, reduced central inhibitory control, and heightened detrusor sensitivity to motor input, with multiple potential causes listed.\"}]","Overactive Bladder and Urge Urinary Incontinence (OAB & UUI) - Outline | PDF",1788753891,93,{"code":4,"msg":32,"data":33},"ok",{"site_id":25,"language":24,"slug":34,"title":13,"keywords":35,"description":14,"schema_data":36,"social_meta":87,"head_meta":89,"extra_data":91,"updated_unix":29},"overactive-bladder-and-urge-urinary-incontinence-oab-uui-outline","",{"@graph":37,"@context":86},[38,54,69],{"@type":39,"itemListElement":40},"BreadcrumbList",[41,45,48,51],{"item":42,"name":43,"@type":44,"position":21},"https://docshare.wps.com","Home","ListItem",{"item":46,"name":47,"@type":44,"position":20},"https://docshare.wps.com/document/","Document",{"item":49,"name":12,"@type":44,"position":50},"https://docshare.wps.com/document/healthcare/",3,{"item":52,"name":13,"@type":44,"position":53},"https://docshare.wps.com/document/overactive-bladder-and-urge-urinary-incontinence-oab-uui-outline/213119/",4,{"url":52,"name":13,"@type":55,"author":56,"headline":13,"publisher":58,"fileFormat":61,"inLanguage":24,"description":14,"dateModified":62,"datePublished":63,"encodingFormat":61,"isAccessibleForFree":64,"interactionStatistic":65},"DigitalDocument",{"name":9,"@type":57},"Person",{"url":42,"name":59,"@type":60},"DocShare","Organization","application/pdf","2026-09-11","2026-09-07",true,{"@type":66,"interactionType":67,"userInteractionCount":20},"InteractionCounter",{"@type":68},"ViewAction",{"@type":70,"mainEntity":71},"FAQPage",[72,78,82],{"name":73,"@type":74,"acceptedAnswer":75},"How are overactive bladder and urge urinary incontinence defined in this outline?","Question",{"text":76,"@type":77},"Overactive bladder is described as a symptom syndrome featuring urinary urgency, with or without urge incontinence, usually accompanied by frequency and nocturia. Urge urinary incontinence is involuntary urine loss that is accompanied by or immediately preceded by urgency.","Answer",{"name":79,"@type":74,"acceptedAnswer":80},"What causes nocturia in the context of OAB & UUI?",{"text":81,"@type":77},"Nocturia is defined as walking to pass urine during the main sleep period, with the first episode occurring after sleep. Nocturnal polyuria is noted when more than 33% of total daily urine output occurs at night or during sleep.",{"name":83,"@type":74,"acceptedAnswer":84},"What pathophysiological mechanisms are discussed for OAB & UUI?",{"text":85,"@type":77},"The outline covers myogenic mechanisms, including detrusor muscle structural/functional alterations, partial denervation, and supersensitivity to acetylcholine with abnormal spontaneous activity. It also describes neurogenic mechanisms such as increased afferent activity, reduced central inhibitory control, and heightened detrusor sensitivity to motor input, with multiple potential causes listed.","https://schema.org",{"og:url":52,"og:type":88,"og:title":13,"og:site_name":59,"og:description":14},"article",{"robots":90,"canonical":52},"index,follow",{"doc_id":7,"site_id":25},{"code":4,"msg":5,"data":93},[94,98,102,106,111,116,119,124,129,132,136],{"id":21,"doc_module":4,"doc_module_name":47,"category_name":95,"show_sort_weight":96,"slug":97},"Story & Novel",90,"story-novel",{"id":20,"doc_module":4,"doc_module_name":47,"category_name":99,"show_sort_weight":100,"slug":101},"Literature",80,"literature",{"id":53,"doc_module":4,"doc_module_name":47,"category_name":103,"show_sort_weight":104,"slug":105},"Exam",70,"exam",{"id":107,"doc_module":4,"doc_module_name":47,"category_name":108,"show_sort_weight":109,"slug":110},5,"Comic",60,"comic",{"id":112,"doc_module":4,"doc_module_name":47,"category_name":113,"show_sort_weight":114,"slug":115},6,"Technology",50,"technology",{"id":11,"doc_module":4,"doc_module_name":47,"category_name":12,"show_sort_weight":117,"slug":118},40,"healthcare",{"id":120,"doc_module":4,"doc_module_name":47,"category_name":121,"show_sort_weight":122,"slug":123},8,"Research & Report",30,"research-report",{"id":125,"doc_module":4,"doc_module_name":47,"category_name":126,"show_sort_weight":127,"slug":128},9,"Religion & Spirituality",20,"religion-spirituality",{"id":127,"doc_module":4,"doc_module_name":47,"category_name":130,"show_sort_weight":127,"slug":131},"World Cup","world-cup",{"id":133,"doc_module":4,"doc_module_name":47,"category_name":134,"show_sort_weight":133,"slug":135},10,"Lifestyle","lifestyle",{"id":137,"doc_module":4,"doc_module_name":47,"category_name":138,"show_sort_weight":107,"slug":139},19,"General","general"]