[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-369044-105":59,"doc-detail-369044-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","ovarian-cancer-metastasis-to-axillary-node-without-breast-involvement-a-rare-case","Ovarian cancer metastasis to axillary node without breast involvement: a rare case","","Ovarian cancer remains the most lethal gynecological malignancy, with limited survival despite advanced multimodality care and no clearly defined precursor lesion. Metastatic spread beyond the abdomen is uncommon, and isolated axillary lymph node involvement without breast disease is particularly rare. A case describes a 54-year-old woman with stage IVB high-grade serous ovarian cancer presenting with persistent right axillary lymphadenopathy. The axillary biopsy confirmed metastatic carcinoma and management included systemic therapy and secondary cytoreductive surgery with HIPEC and ALND.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/ovarian-cancer-metastasis-to-axillary-node-without-breast-involvement-a-rare-case/369044/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/ovarian-cancer-metastasis-to-axillary-node-without-breast-involvement-a-rare-case/369044.png","ImageObject",300,407,{"name":92,"@type":93},"acoobca","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-01","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why is axillary lymph node metastasis without breast involvement notable in ovarian cancer?","Question",{"text":113,"@type":114},"It is a very rare presentation, as distant metastasis outside the abdomen is uncommon and axillary involvement typically occurs without breast disease in exceptional cases.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What treatments were used after the axillary node metastasis was confirmed?",{"text":118,"@type":114},"The patient received second-line chemotherapy, followed by secondary cytoreductive surgery with HIPEC (cisplatin) and right level I ALND.",{"name":120,"@type":111,"acceptedAnswer":121},"What was concluded about evaluating patients with axillary lymphadenopathy?",{"text":122,"@type":114},"Meticulous evaluation is emphasized to rule out ovarian cancer, and axilla should be considered a potential metastasis site in known ovarian carcinoma for effective treatment planning.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},369044,1790231725,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},3985747870733,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Das and Ray Journal of Ovarian Research (2026) 19:23 Journal of Ovarian Research  \n[https://doi.org/10.1186/s13048-025-01904-y](https://doi.org/10.1186/s13048-025-01904-y)  \nCASE REPORT Open Access  \nOvarian cancer metastasis to axillary node without breast involvement: a rare case  \nShaon Das 1* and Major MD Ray1  \nAbstract  \nBackground Ovarian cancer is the most lethal gynaecological cancer globally. Despite advanced multimodality treatment 5year survival is around 50% and its only 31% in stage IV cancers. There is no clearly defined precursor lesion. The events which led to metastasis is not clearly understood. Epithelial ovarian cancers (EOC) are the most common type of ovarian malignancy. Stage IV ovarian cancer incidence are raising day by day. Peritoneum is the most common site of recurrence followed by nodes and intra-abdominal metastasis. Distant metastasis outside abdomen is rare. Moreover, ovarian cancer with metastasis to axillary lymph node is very rare presentation specially when breast isnot involved.  \nCase presentation We like to report a case of 54year old lady, who was admitted with persistent Right axillary lymph nodal mass. She had a history of High grade serous ovarian cancer stage IVB which was detected and treated 3 years back with neoadjuvant chemo followed by interval cytoreductive surgery followed by Adjuvant multiple line of chemo and maintenance bevacizumab. During follow up, patient had increased Ca-125, and PET CT suggestive of persisting right axillary LN with retroperitoneal LN and right external iliac node. The axillary node was biopsied and found to be metastatic High-grade Serous Ovarian Carcinoma, but mammography showed no abnormality in bilateral breasts. Patient received 2nd line chemotherapy. Secondary Cytoreductive Surgery and HIPEC (cisplatin) and Right Level I ALND done in Department of Surgical Oncology AIIMS, New Delhi. Intraoperatively 3 × 3 cm Right axillary level I single node found. Excision of metastatic axillary node shows excellent result.  \nConclusion This case highlights the importance of meticulous evaluation of patient presenting with axillary lymphadenopathy to rule out possibility of ovarian cancer. Additionally, axilla should also be considered as a possible site of metastasis in a known case of carcinoma ovary for effective treatment planning.  \nKeywords Case report, Ovarian cancer, Axillary lymph node, Gynaecological malignancy  \n*Correspondence:  \nShaon Das  \n[Das.shaon17@gmail.com](Das.shaon17@gmail.com)  \n1Department of Surgical Oncology, IRCH, All India Institute of Medical Science, New Delhi, India  \n© The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit [http://creati](http://creati)[vecommons.org/licenses/by-nc-nd/4.0/](vecommons.org/licenses/by-nc-nd/4.0/.)[.](vecommons.org/licenses/by-nc-nd/4.0/.)  \nDas and Ray Journal of Ovarian Research (2026) 19:23  \nBackground  \nOvarian Cancer is second most common Gynaecological malignancy worldwide and most common cause of mortality among Gynaecological malignancy in resource abundant countries [1]","cbCaieyMbpC1Ao0B","https://ap.wps.com/l/cbCaieyMbpC1Ao0B","pdf",993806,"English","# Abstract\n# Background\n# Case presentation\n# Conclusion\n# Keywords","[{\"question\":\"Why is axillary lymph node metastasis without breast involvement notable in ovarian cancer?\",\"answer\":\"It is a very rare presentation, as distant metastasis outside the abdomen is uncommon and axillary involvement typically occurs without breast disease in exceptional cases.\"},{\"question\":\"What treatments were used after the axillary node metastasis was confirmed?\",\"answer\":\"The patient received second-line chemotherapy, followed by secondary cytoreductive surgery with HIPEC (cisplatin) and right level I ALND.\"},{\"question\":\"What was concluded about evaluating patients with axillary lymphadenopathy?\",\"answer\":\"Meticulous evaluation is emphasized to rule out ovarian cancer, and axilla should be considered a potential metastasis site in known ovarian carcinoma for effective treatment planning.\"}]","Ovarian cancer metastasis to axillary node without breast involvement: a rare case | PDF",1790180335,13]