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This retrospective study compares robotic liver resection (R-LR) with robotic intraoperative RFA (RIO-RFA) using propensity score matching to address selection bias. Among 93 patients treated between 2015 and 2024, overall survival and recurrence-free survival were similar for de novo cases, while recurrent disease showed better survival after R-LR. Tumor size, platelet count, and postoperative complications were key prognostic factors, supporting individualized treatment selection.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/outcomes-of-robotic-liver-resection-and-intraoperative-radiofrequency-ablation-for-hepatocellular-carcinoma-in-posterior-segments-vii-and-viii/406497/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/outcomes-of-robotic-liver-resection-and-intraoperative-radiofrequency-ablation-for-hepatocellular-carcinoma-in-posterior-segments-vii-and-viii/406497.png","ImageObject",300,407,{"name":92,"@type":93},"McQueen","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What clinical comparison does the study evaluate?","Question",{"text":112,"@type":113},"It compares clinical outcomes of robotic liver resection (R-LR) versus robotic intraoperative RFA (RIO-RFA) for hepatocellular carcinoma in posterior segments VII and VIII.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How did the outcomes differ between de novo and first recurrent HCC?",{"text":117,"@type":113},"For de novo HCC, overall survival and recurrence-free survival did not differ significantly between R-LR and RIO-RFA. For recurrent HCC, R-LR showed significantly improved overall and recurrence-free survival.",{"name":119,"@type":110,"acceptedAnswer":120},"What factors were identified as key prognostic indicators?",{"text":121,"@type":113},"Tumor size, platelet count, and postoperative complications were reported as key prognostic factors influencing survival and recurrence outcomes.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},406497,1790762972,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":56,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},5909890329169,"https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc","| W | J | G | S | World Journal of\u003Cbr>Gastrointestinal Surgery |\n| --- | --- | --- | --- | --- |\n\nSubmit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Gastrointest Surg 2025 December 27; 17(12): 113940  \nDOI: 10.4240/wjgs.v17.i12.113940 ISSN 1948-9366 (online)  \nORIGINAL ARTICLE  \nRetrospective Study  \nOutcomes of robotic liver resection and intraoperative radiofrequency ablation for hepatocellular carcinoma in posterior segments VII and VIII  \nCheng-Ming Peng, Shao-Chieh Lin, Yung-Yin Cheng, Teng-Chieh Cheng, Ching-Lung Hsieh, Chia-Hong Hsieh, Mei-Fang Hsieh, Chun-Han Liao, Ming-Cheng Liu, Yi-Jui Liu  \nSpecialty type: Gastroenterology and hepatology  \nProvenance and peer review:  \nInvited article; Externally peer reviewed.  \nPeer-review model: Single blind  \nPeer-review report’s classification Scientific Quality: Grade A, Grade A  \nNovelty: Grade A, Grade A  \nCreativity or Innovation: Grade A, Grade A  \nScientific Significance: Grade A, Grade A  \nP-Reviewer: Li JT, MD, Assistant Professor, China  \nReceived: September 8, 2025  \nRevised: September 24, 2025  \nAccepted: October 28, 2025  \nPublished online: December 27, 2025  \nProcessing time: 108 Days and 19.8 Hours  \nCheng-Ming Peng, Ching-Lung Hsieh, Department of Surgery, Chung Shan Medical University Hospital, Taichung 40201, Taiwan  \nCheng-Ming Peng, School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan  \nShao-Chieh Lin, Yung-Yin Cheng, Chia-Hong Hsieh, Mei-Fang Hsieh, Chun-Han Liao, Ph.D. Program of Electrical and Communications Engineering, Feng Chia University, Taichung 407, Taiwan  \nYung-Yin Cheng, Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung 402, Taiwan  \nTeng-Chieh Cheng, Da Vinci Minimally Invasive Surgery Center, Chung Shan Medical University Hospital, Taichung 40201, Taiwan  \nChing-Lung Hsieh, Department of Computer Science and Information Engineering, Feng Chia University, Taichung 40724, Taiwan  \nChia-Hong Hsieh, Department of Radiology, Taichung Armed Forces General Hospital, Taichung 411, Taiwan  \nMei-Fang Hsieh, Chun-Han Liao, Department of Medical Imaging, Changhua Christian Hospital, Changhua 500, Taiwan  \nChun-Han Liao, Division of Medical Imaging, Yuanlin Christian Hospital, Changhua 510, Taiwan  \nMing-Cheng Liu, Department of Medical Imaging, Taichung Veterans General Hospital, Taichung 407, Taiwan  \nYi-Jui Liu, Department of Automatic Control Engineering, Feng Chia University, Taichung 407, Taiwan  \nCorresponding author: Yi-Jui Liu, PhD, Professor, Department of Automatic Control Engineering, Feng Chia University, No. 100 Wenhwa Road, Seatwen, Taichung 407, Taiwan.  \n WJGS  [https://www.wjgnet.com](https://www.wjgnet.com) 1 December 27, 2025  Volume 17  Issue 12   \nPeng MC et al. Resection or ablation for challenging HCC  \n[erliu@fcu.edu.tw](erliu@fcu.edu.tw)  \nAbstract  \nBACKGROUND  \nHepatocellular carcinoma (HCC) in segments VII and VIII poses technical challenges for both liver resection and radiofrequency ablation (RFA) . Robotic-assisted techniques may enhance safety and precision, but comparative evidence remains limited.  \nAIM  \nTo compare the clinical outcomes of robotic liver resection (R-LR) and robotic intraoperative RFA (RIO-RFA) for HCC located in liver segments VII and VIII.  \nMETHODS  \nWe retrospectively analyzed 93 HCC patients in segments VII/VIII with de novo (n = 57) or first recurrent (n = 36) . HCC who underwent R-LR or RIO-RFA between 2015 and 2024. Propensity score matching was performed to reduce selection bias. Primary outcomes were overall survival (OS) and recurrence-free survival (RFS) . KaplanMeier curves, log-rank tests, and Cox regression were used to identify prognostic factors for OS and RFS.  \nRESULTS  \nIn the de novo group, OS and RFS did not differ significantly between R-LR and RIO-RFA before or after propensity score matching. In contrast, the recurrent group showed significantly improved OS and RFS with R-LR (P = 0.005 and P =","cbCaimIZJiL5IUVD","https://ap.wps.com/l/cbCaimIZJiL5IUVD","pdf",1974694,"English","# Abstract\n## Background\n## Aim\n## Methods\n## Results\n## Conclusion\n# Core Tip\n# Citation","[{\"question\":\"What clinical comparison does the study evaluate?\",\"answer\":\"It compares clinical outcomes of robotic liver resection (R-LR) versus robotic intraoperative RFA (RIO-RFA) for hepatocellular carcinoma in posterior segments VII and VIII.\"},{\"question\":\"How did the outcomes differ between de novo and first recurrent HCC?\",\"answer\":\"For de novo HCC, overall survival and recurrence-free survival did not differ significantly between R-LR and RIO-RFA. For recurrent HCC, R-LR showed significantly improved overall and recurrence-free survival.\"},{\"question\":\"What factors were identified as key prognostic indicators?\",\"answer\":\"Tumor size, platelet count, and postoperative complications were reported as key prognostic factors influencing survival and recurrence outcomes.\"}]","Outcomes of robotic liver resection and intraoperative radiofrequency ablation for hepatocellular carcinoma in posterior segments VII and VIII | PDF",1790566081,48]