[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-265953-105":3,"doc-detail-265953-en":81,"detail-sidebar-cat-0-en-105":97},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","outcomes-of-endovascular-treatment-for-infrapopliteal-peripheral-artery-disease-based-on-the-updated-tasc-ii-classification","Outcomes of Endovascular Treatment for Infrapopliteal Peripheral Artery Disease Based on the Updated TASC II Classification","","We retrospectively analyzed 383 infrapopliteal arterial lesions treated endovascularly in 270 patients at a single institution from December 2008 to January 2018. Technical success reached 97% overall, including 98% for stenoses and 95% for occlusions. TASC II categories did not affect technical success. Clinically driven target lesion revascularization (TLR) freedom remained 88.3% at 6 months and 77.2% at 12 months. Multivariate modeling identified TASC D lesions, Fontaine III–IV class, and occlusive lesions as independent predictors for higher TLR risk, supporting safety and favorable long-term outcomes.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/research-report/","Research & Report",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/outcomes-of-endovascular-treatment-for-infrapopliteal-peripheral-artery-disease-based-on-the-updated-tasc-ii-classification/265953/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/outcomes-of-endovascular-treatment-for-infrapopliteal-peripheral-artery-disease-based-on-the-updated-tasc-ii-classification/265953.png","ImageObject",300,407,{"name":42,"@type":43},"Emma Wilson","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-11-05","2026-09-14",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",12,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What were the technical success rates of the endovascular procedures in this study?","Question",{"text":63,"@type":64},"The overall technical success rate was 97%. Success was 98% for stenoses and 95% for occlusions.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"Did the updated TASC II classification affect technical success rates?",{"text":68,"@type":64},"No. Technical success did not differ significantly between TASC A+B and TASC C+D groups.",{"name":70,"@type":61,"acceptedAnswer":71},"Which factors predicted clinically driven TLR after treatment?",{"text":72,"@type":64},"Multivariate analysis identified TASC D lesions, Fontaine class III and IV, and occlusive lesions as predictors for TLR.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},265953,1789402767,{"code":4,"msg":82,"data":83},"success",{"doc_id":79,"user_id":84,"nickname":42,"user_avatar":85,"doc_module":4,"category_id":86,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":87,"file_id":88,"file_url":89,"file_type":90,"file_size":91,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":86,"language":92,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":93,"faqs":94,"seo_title":95,"seo_description":12,"update_tm":80,"read_time":96,"preview_page_count":4},3848291630094,"https://eur-avatar.wpscdn.com/davatar_085a072bc5b1113ac321206ff7593b45",8,"Original Article  \nOutcomes of endovascular treatment for infrapopliteal peripheral artery disease based on the updated TASC II classification  \nArne M Müller 1, Veronika Räpple 1, Christian Bradaric 1, Tobias Koppara 1, Victoria Kehl2, Massimiliano Fusaro3, Salvatore Cassese3, Ilka Ott4, Adnan Kastrati3,5,  \nKarl-Ludwig Laugwitz 1,5 and Tareq Ibrahim 1  \nVascular Medicine  \n1–8 © The Author(s) 2020 Article reuse guidelines:  \n[sagepub.com/journals-permissions](sagepub.com/journals-permissions)[ ](sagepub.com/journals-permissions)[DOI: 10.1177/1358863X20967091](DOI: 10.1177/1358863X20967091)[ ](DOI: 10.1177/1358863X20967091)[journals.sagepub.com/home/vmj](journals.sagepub.com/home/vmj)  \nAbstract  \nWe retrospectively analyzed all endovascular procedures of infrapopliteal arterial lesions (n = 383) performed in 270 patients at our institution between December 2008 and January 2018. The overall technical success rate was 97% and yielded 98% for stenoses (n = 214) and 95% for occlusions (n = 169). Trans-Atlantic Inter-Society Consensus (TASCII) classification had no impact on success rates (TASC A + B vs C + D; 96.5% vs 96.9%, p = 0.837). Freedom from clinically driven target lesion revascularization (TLR) after 6 and 12 months was 88.3% and 77.2%. TLR was comparable for TASC A to C lesions and no difference was observed comparing groups of moderately complex TASC A/B lesions and more complex TASC C/D lesions (TASC A + B vs C + D; 78.5% vs 74.2%, p = 0.457). Freedom from TLR was significantly lower in very complex TASC D lesions (TASC A + B + C vs D; 79.7% vs 42.5%, p \u003C 0.001). Multivariate analysis identified TASC D lesions (hazard ratio D/A: 1.5; overall p = 0.002), Fontaine class III and IV (hazard ratio III or IV/IIa or IIb: 2.4; p = 0.041), and occlusive lesions (hazard ratio occlusion/stenosis: 2.4; p = 0.026) as predictors for TLR. In conclusion, endovascular therapy for infrapopliteal artery disease was safe and accompanied with a promising long-term outcome.  \nKeywords  \nangioplasty, atherosclerosis, endovascular procedures, infrapopliteal arteries, peripheral artery disease (PAD)  \nIntroduction  \nPeripheral artery disease (PAD) is common, showing high prevalence rates of up to 15–20%, increasing with age.1–6 In these patients, arterial stenoses or occlusions may be present anywhere from the aortic bifurcation downstream to the pedal arteries of the lower limb. By far the most frequently underlying pathology observed is atherosclerosis, but in rare cases may also be linked to arteritis, radiation injury, trauma, or embolism.7 Typical symptoms comprise intermittent claudication, rest pain or ulcer of the foot. However, with the infrapopliteal arteries being the vascular territory located atthe very periphery of the vascular system, a variety of chal  \nlenges regarding both diagnostics as well as therapy arise.  \nRecently, endovascular therapy has emerged as an established treatment option in PAD. In the light of an ongoing lack of randomized trials addressing treatment options for lower limb PAD, treatment strategies are based on expert recommendations such as the Inter-Society Consensus Documents for the Management of Peripheral Arterial Disease (Trans-Atlantic Inter-Society Consensus [TASC] I and II), the ESC (European Society of Cardiology) or AHA  \n(American Heart Association) Guidelines.7–10 In general, a paradigm shift in treatment strategies for PAD could be observed over the years towards an endovascular-first approach for the majority of even anatomically complex  \n1 Klinikum rechts der Isar, Klinik und Poliklinik für Innere Medizin I., Technische Universität München, Munich, Germany  \n2Klinikum rechts der Isar, Institut für Medizinische Informatik, Statistik und Epidemiologie, Technische Universität München, Munich, Germany  \n3Deutsches Herzzentrum München, Abteilung für Herz-und Kreislauferkrankungen, Technische Universität München, Munich, Germany  \n4Helios Klinikum Pforzheim, Abteilung für Kardiologie, Angiol","cbCaimycxMoFCGJ8","https://ap.wps.com/l/cbCaimycxMoFCGJ8","pdf",474639,"English","# Abstract\n# Introduction\n# Methods\n## Patients","[{\"question\":\"What were the technical success rates of the endovascular procedures in this study?\",\"answer\":\"The overall technical success rate was 97%. Success was 98% for stenoses and 95% for occlusions.\"},{\"question\":\"Did the updated TASC II classification affect technical success rates?\",\"answer\":\"No. Technical success did not differ significantly between TASC A+B and TASC C+D groups.\"},{\"question\":\"Which factors predicted clinically driven TLR after treatment?\",\"answer\":\"Multivariate analysis identified TASC D lesions, Fontaine class III and IV, and occlusive lesions as predictors for TLR.\"}]","Outcomes of Endovascular Treatment for Infrapopliteal Peripheral Artery Disease Based on the Updated TASC II Classification | PDF",20,{"code":4,"msg":82,"data":98},[99,103,107,111,116,121,126,129,133,136,140],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":100,"show_sort_weight":101,"slug":102},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":104,"show_sort_weight":105,"slug":106},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":108,"show_sort_weight":109,"slug":110},"Exam",70,"exam",{"id":112,"doc_module":4,"doc_module_name":25,"category_name":113,"show_sort_weight":114,"slug":115},5,"Comic",60,"comic",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":118,"show_sort_weight":119,"slug":120},6,"Technology",50,"technology",{"id":122,"doc_module":4,"doc_module_name":25,"category_name":123,"show_sort_weight":124,"slug":125},7,"Healthcare",40,"healthcare",{"id":86,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":127,"slug":128},30,"research-report",{"id":130,"doc_module":4,"doc_module_name":25,"category_name":131,"show_sort_weight":96,"slug":132},9,"Religion & Spirituality","religion-spirituality",{"id":96,"doc_module":4,"doc_module_name":25,"category_name":134,"show_sort_weight":96,"slug":135},"World Cup","world-cup",{"id":137,"doc_module":4,"doc_module_name":25,"category_name":138,"show_sort_weight":137,"slug":139},10,"Lifestyle","lifestyle",{"id":141,"doc_module":4,"doc_module_name":25,"category_name":142,"show_sort_weight":112,"slug":143},19,"General","general"]