[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-379272-105":59,"doc-detail-379272-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","oral-complications-from-oropharyngeal-cancer-therapy-review","Oral Complications from Oropharyngeal Cancer Therapy - Review","","Post-oropharyngeal cancer therapy can lead to numerous oral side effects that affect overall survival and quality of life. The review covers acute and chronic complications in the oral cavity and head and neck, including mucositis, infection, xerostomia, dysgeusia, radiation caries, osteonecrosis, and trismus. It highlights that many cited studies combine oropharyngeal and head and neck results, and specifies when guidance applies specifically to oropharyngeal cancers.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/oral-complications-from-oropharyngeal-cancer-therapy-review/379272/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/oral-complications-from-oropharyngeal-cancer-therapy-review/379272.png","ImageObject",300,407,{"name":92,"@type":93},"Cart","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",13,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What oral complications can occur after oropharyngeal cancer therapy?","Question",{"text":113,"@type":114},"The review identifies common acute and chronic oral complications such as mucositis, infections (including candidiasis), xerostomia, dysgeusia, radiation caries, osteonecrosis, and trismus.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"Why do side effects after treatment vary among patients?",{"text":118,"@type":114},"Side effects may be acute or chronic and differ by cancer stage, location, and the treatment modalities and intensity used.",{"name":120,"@type":111,"acceptedAnswer":121},"How do the authors address differences between oropharyngeal and head and neck research in the literature?",{"text":122,"@type":114},"The review notes that the literature often combines oropharyngeal and head and neck cancer results, and it highlights recommendations that are strictly related to oropharyngeal cancers.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},379272,1790288863,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":36},18829141979164,"https://eur-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","cancers   \nReview  \nOral Complications from Oropharyngeal Cancer Therapy Vidya Sankar * and Yuanming Xu   \nCitation: Sankar, V.; Xu, Y. Oral Complications from Oropharyngeal Cancer Therapy. Cancers 2023, 15, 4548. [https://doi.org/10.3390/](https://doi.org/10.3390/)[ ](https://doi.org/10.3390/)cancers15184548  \nAcademic Editor: Maria Lina Tornesello  \nReceived: 15 August 2023  \nRevised: 7 September 2023  \nAccepted: 11 September 2023  \nPublished: 14 September 2023  \nCopyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ([https://](https://)[ ](https://)[creativecommons.org/licenses/by/](creativecommons.org/licenses/by/)[ ](creativecommons.org/licenses/by/)[4.0/](4.0/)) .  \nDepartment of Diagnostic Sciences, Tufts University School of Dental Medicine, Boston, MA 02111, USA; [yuanming.xu@tufts.edu](yuanming.xu@tufts.edu)  \n* [Correspondence: vidya.sankar@tufts.edu](Correspondence: vidya.sankar@tufts.edu); Tel.: +1-210-643-4946  \nSimple Summary: Although oropharyngeal cancers are increasing in incidence, more patients are surviving their cancer therapy. Once a patient has completed their oropharyngeal cancer treatment, they need to contend with the multiple side effects related to their cancer treatment. These factors may be acute or chronic and vary from individual to individual, depending on the cancer stage, location, and treatment modalities employed. These treatment-related side effects have an impact on their overall survival and quality of life domains such as function, taste, speech, dry mouth, dental decay, oral infection, bone necrosis, and nutrition. This review will summarize the most common oral complications from oropharyngeal cancer therapy, their causes, ways to help reduce the occurrences, and guidelines related to monitoring and treatment of the conditions.  \nAbstract: Post-oropharyngeal cancer treatment complications include a multitude of oral side effects that impact overall survival and quality of life. These include acute and chronic conditions affecting the oral cavity and head and neck, such as mucositis, infection, xerostomia, dysgeusia, radiation caries, osteonecrosis, and trismus. This review will summarize the most common oral complications from oropharyngeal cancer therapy. The authors would like to point out that the literature cited frequently combines oropharyngeal and head and neck cancer results. If recommendations are made strictly related to oropharyngeal cancers, this will be highlighted.  \nKeywords: oropharyngeal cancer; dysgeusia; xerostomia; radiation caries; osteoradionecrosis; salivary gland dysfunction; mucositis  \n1. Introduction  \nOropharyngeal cancers are increasing in incidence; it is estimated that new cases and deaths will be 54,540 and 11,580, respectively, in 2023 [1] . There were 16.9 million cancer survivors in the United States in 2019, with projected increases to 22.2 million by 2030 [1] . Although the number of cases is increasing, the risk of death from oropharyngeal cancer is decreasing, broadly attributed to overall decreases in smoking, early detection, surgical techniques, and the implementation of targeted therapies [2] .  \nThese gains in survival come with acute and long-term consequences associated with side effects from their cancer treatment, including organ damage and functional impairments, which vary depending on the particular cancer treatment modality, the intensity of treatment, and/or combinations of treatment modalities. Methods used to reduce treatment-related side effects include the use of minimally invasive surgical techniques when possible. These include transoral robotic surgery (TORS) and transoral laser microsurgery (TLM) . Compared with open surgery, a smaller incision is made, and telescopes and surgical blades are inserted. The approach allows for greater precision in tumor resection, leading to decr","cbCaigrfiTk1GTTs","https://ap.wps.com/l/cbCaigrfiTk1GTTs","pdf",328056,16,"English","# Simple Summary\n# Abstract\n# Keywords\n# 1. Introduction\n## Epidemiology and survivorship trends\n## Treatment approaches and side-effect reduction methods","[{\"question\":\"What oral complications can occur after oropharyngeal cancer therapy?\",\"answer\":\"The review identifies common acute and chronic oral complications such as mucositis, infections (including candidiasis), xerostomia, dysgeusia, radiation caries, osteonecrosis, and trismus.\"},{\"question\":\"Why do side effects after treatment vary among patients?\",\"answer\":\"Side effects may be acute or chronic and differ by cancer stage, location, and the treatment modalities and intensity used.\"},{\"question\":\"How do the authors address differences between oropharyngeal and head and neck research in the literature?\",\"answer\":\"The review notes that the literature often combines oropharyngeal and head and neck cancer results, and it highlights recommendations that are strictly related to oropharyngeal cancers.\"}]","Oral Complications from Oropharyngeal Cancer Therapy - Review | PDF",1790234826]