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Methods: Clinical data were reviewed for thoracic OVCF patients with costal pain admitted between January 2021 and January 2024; an observation group received percutaneous vertebroplasty (PVP) plus INB, while controls received PVP alone. Multivariable logistic regression and ROC analyses identified risk factors for residual costal pain. Results: 305 patients were included (150 vs 155). Both groups improved deformity and pain similarly, but observation required longer operative time and more C-arm fluoroscopy. Disease duration independently predicted residual costal pain (AUC=0.863), with a 15.5-day threshold. Conclusions: PVP combined with INB alleviates OVCF-related costal pain effectively, but INB increases operative time and radiation exposure.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/optimizing-outcomes-in-vertebral-fractures-the-impact-of-intercostal-nerve-block-on-costal-pain/438338/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/optimizing-outcomes-in-vertebral-fractures-the-impact-of-intercostal-nerve-block-on-costal-pain/438338.png","ImageObject",300,407,{"name":92,"@type":93},"ahduag","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":24},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the main objective of this study?","Question",{"text":112,"@type":113},"To evaluate how effective intercostal nerve block (INB) is when added to percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCFs) with costal pain.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were patients grouped in the study?",{"text":117,"@type":113},"Patients with thoracic OVCF and costal pain were assigned to an observation group receiving PVP plus INB, or a control group receiving PVP alone.",{"name":119,"@type":110,"acceptedAnswer":120},"Which factors predicted residual costal pain in the control group?",{"text":121,"@type":113},"Multivariable analysis confirmed disease duration as an independent risk factor for residual costal pain, and the self-resolution threshold was 15.5 days.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},438338,1790781969,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":24,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":39,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":46,"preview_page_count":4},3985747870414,"https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc","Wiley  \nJournal of Osteoporosis  \nVolume 2025, Article ID 5595038, 8 pages [https://doi.org/10.1155/joos/5595038](https://doi.org/10.1155/joos/5595038)  \nResearch Article  \nOptimizing Outcomes in Vertebral Fractures: The Impact of Intercostal Nerve Block on Costal Pain  \nZiyao Ma , 1 Xuelian Peng,2 Shuang Xu,3 Qing Wang,3 and Shuai Zhang 3  \n1 Southwest Medical University, Luzhou 646000, Sichuan, China  \n2 Department of Ultrasound, Te Afliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China 3 Department of Orthopedics, Te Afliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China  \nCorrespondence should be addressed to Shuai Zhang; [zsspine199208@sina.com](zsspine199208@sina.com)  \nReceived 7 September 2025; Revised 16 October 2025; Accepted 25 November 2025  \nAcademic Editor: Francisco Curate  \nCopyright © 2025 Ziyao Ma et al. Journal of Osteoporosis published by John Wiley & Sons Ltd. Tis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.  \nObjective: To assess the efectiveness of intercostal nerve block (INB) for treating osteoporotic vertebral compression fractures (OVCFs) with associated costal pain.  \nMethods: We reviewed clinical data from patients with thoracic OVCF and costal pain admitted to our hospital between January 2021 and January 2024 . Patients were divided into an observation group, receiving percutaneous vertebroplasty (PVP) and INB, and a control group, receiving PVP alone. Baseline data, intraoperative parameters, deformity improvement (anterior vertebral body height [AVH] and local Cobb angle), and clinical symptom improvement (visual analog scale [VAS] scores for back and costal pain) were compared between the groups. Risk factors for residual costal pain within the control group were analyzed using multivariable logistic regression, and receiver operating characteristic (ROC) curves were constructed to determine threshold values for the identifed risk factors.  \nResults: Te study included 305 patients, 150 in the observation group and 155 in the control group. Te groups were statistically comparable in baseline data. Compared with the control group, the observation group had a longer operative time (40.7 ± 5.5 vs. 32.4 ± 3.8 min, p \u003C 0.001) and required more intraoperative C-arm fuoroscopies (30.4 ± 6.3 vs. 21.5 ± 3.9, p 􀂈 0.034) . Intraoperative bleeding was similar between groups. Both groups showed similarly signifcant improvements in AVH, local Cobb angle, and thoracic back pain VAS scores one day postoperatively and at the fnal follow-up. Te respective costal pain VAS scores in the control and observation groups were as follows: preoperatively, 7 (6, 8) and 7 (6, 7); one day postoperatively, 4 (2, 5) and 2 (1, 2); and at the fnal follow-up, 1 (1, 2) and 1 (0, 2) . Univariate analysis within the control group identifed disease duration, fractured vertebral body width, reduced intervertebral foramen area, and cortical breakdown of the vertebral body’s posterior wall as risk factors for residual costal pain. Multivariable analysis confrmed disease duration as an independent risk factor for residual costal pain, with an area under the curve of 0.863 . Te threshold for self-resolution of costal pain was established at 15.5 days, with a sensitivity of 93.9% and a specifcity of 70.0% . Costal pain relief was strongly correlated with disease duration (r 􀂈 0.518, p \u003C 0.001) .  \nConclusions: OVCF-related costal pain can be efectively alleviated by PVP combined with INB; however, INB lengthens operative time and increases radiation exposure. PVP alone can relieve costal pain in patients with a disease duration of ≤ 15.5 days; otherwise, concomitant INB is recommended.  \nKeywords: costal pain; disease duration; intercostal nerve block; osteoporotic vertebral compression fracture; percutaneous vertebroplasty  \n2 Journal o","cbCaiq5E9bYjQWIq","https://ap.wps.com/l/cbCaiq5E9bYjQWIq","pdf",561859,"English","# Objective\n# Methods\n## Patient Selection\n# Results\n# Conclusions\n# Keywords","[{\"question\":\"What was the main objective of this study?\",\"answer\":\"To evaluate how effective intercostal nerve block (INB) is when added to percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCFs) with costal pain.\"},{\"question\":\"How were patients grouped in the study?\",\"answer\":\"Patients with thoracic OVCF and costal pain were assigned to an observation group receiving PVP plus INB, or a control group receiving PVP alone.\"},{\"question\":\"Which factors predicted residual costal pain in the control group?\",\"answer\":\"Multivariable analysis confirmed disease duration as an independent risk factor for residual costal pain, and the self-resolution threshold was 15.5 days.\"}]","Optimizing Outcomes in Vertebral Fractures - The Impact of Intercostal Nerve Block on Costal Pain | PDF",1790685050]