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Ten healthy volunteers underwent manual planning of short-axis cine acquisitions twice by one operator and once by a second operator. Intra- and inter-observer variability were assessed for LV volume, mass, and ejection fraction using reproducibility metrics including Bland-Altman limits and plane alignment deviation.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/operator-induced-variability-in-cardiovascular-mr-left-ventricular-measurements-and-their-reproducibility/631046/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/operator-induced-variability-in-cardiovascular-mr-left-ventricular-measurements-and-their-reproducibility/631046.png","ImageObject",300,407,{"name":92,"@type":93},"Himbo","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-10","2026-10-22",true,{"@type":102,"interactionType":103,"userInteractionCount":19},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the purpose of the study?","Question",{"text":112,"@type":113},"To assess intra- and inter-operator variability in manual planning for cardiovascular MR and to evaluate its influence on left ventricular functional parameters.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the imaging planning performed and who analyzed the data?",{"text":117,"@type":113},"Short-axis cine acquisitions were manually planned twice by one operator and once by a second operator. Left ventricular volume, mass, and function were manually evaluated twice by one experienced observer.",{"name":119,"@type":110,"acceptedAnswer":120},"What did the results show about reproducibility?",{"text":121,"@type":113},"Variability differed by parameter, with small absolute differences and no significant statistical differences between intra- and inter-operator reproducibility. Bland-Altman analysis indicated no systematic bias in measurement differences.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},631046,1792674783,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":19,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},687197100911,"https://ap-avatar.wpscdn.com/avatar/a000239b6f1da00475?x-image-process=image/resize,m_fixed,w_180,h_180&k=1785132997149421697","Journal of Cardiovascular Magnetic Resonance (2005) 7, 447–457 Copyright D 2005 Taylor & Francis Inc.  \nISSN: 1097-6647 print / 1532-429X online  \nDOI: 10.1081/JCMR-200053578  \nVENTRICULAR FUNCTION  \nOperator induced variability in cardiovascular MR: left ventricular measurements and their reproducibility  \nMIKHAIL G. DANILOUCHKINE, PH.D., JOS J. M. WESTENBERG, ALBERT DE ROOS, JOHAN H. C. REIBER,* and BOUDEWIJN P. F. LELIEVELDT  \nDivision of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands  \nPurpose. To assess the intra- and inter-operator variability of the manual planning of cardiovascular magnetic resonance imaging and to evaluate the influence of these factors on the functional parameters of the left ventricle (LV) . Method. The study population consisted of 10 healthy volunteers. For each subject the manual planning of the short-axis cine acquisitions was carried out twice by one operator and once by a second operator. Left ventricular volume, mass, and function were manually evaluated twice by one experienced observer, resulting in an approximation of the intra-observer variability factor. The intra- and inter-operator variation factors were estimated as the difference between the total and intra-observer variation components. Results. LV end-diastolic volume varied by 3.3% and 4.16%, and LV end-systolic volume by 5.84% and 6.23% for intra-and inter-operator studies, respectively. The variability for LV mass at end-diastole was equal to 4.23% in both studies. For the ejection fraction the variability was 3.56% and 2.97% for intra- and inter-operator studies, respectively. Comparison of reproducibility between intra-and inter-operator studies resulted in insignificant statistical differences. BlandAltman limits of agreements revealed no systematic bias in differences between measurements with respect to their means. Reliability of the planning expressed as the angular deviation of the short-axis imaging planes amounts to 2 .67 ± 1 .5􀀁 and 4 .99 ± 2 .17􀀁 for the intra-operator and inter-operator studies, respectively. For EDV, ESV, and EF approximately 75–80% of the total variation can be explained by the within or between operator variation, while the same percentage is 60% for LVM. Conclusions. Our study confirms the excellent inter-and intraoperator reproducibility of the cardiovascular magnetic resonance measurements of the left ventricular volumes and mass in a group of healthy volunteers.  \nKey Words: Left ventricle; Magnetic resonance imaging; Ventricular function; Intra- and inter-operator variability  \n1. Introduction  \nThe precise evaluation of cardiac volume, mass, and function plays an important role in the understanding and consequent treatment of many myocardial diseases (1, 2) . The most widely available technique for this purpose is two-dimensional echocardiography. Although the image acquisition using this technique is highly reproducible in normal individuals, the quantitative analysis heavily relies on geometric assumptions about the shape of the human heart in these two-dimensional images (3–5) . An alternative to echocardiography is cardiovascular magnetic resonance (CMR) imaging, which is free from any geometric assumptions because of its truly three-dimensional characteristics and has been proven to be precise (6–8) and reproducible (9–19) .  \nReceived 6 May 2004; accepted 25 August 2004 .  \n*Address correspondence to Johan H. C. Reiber, Ph.D., Division of Image Processing, Bld. 1, C2S/C3Q, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands; E-mail:  \n[J.H.C.Reiber@lumc.nl](J.H.C.Reiber@lumc.nl)  \nThe precision and reproducibility of the results of the quantitative analysis determine the usability of an imaging modality in the clinical environment. Although there is no doubt about the importance of the precise measurements, reproducibility of the quantitative results becomes equally crucial in specific settings, such as","cbCaig13kjrnCUuc","https://ap.wps.com/l/cbCaig13kjrnCUuc","pdf",401562,11,"English","# Introduction\n## Purpose and approach\n# Method\n## Study population and manual planning\n# Results\n## Variability in LV volumes, mass, and ejection fraction\n## Statistical comparison and agreement analysis\n# Conclusions","[{\"question\":\"What was the purpose of the study?\",\"answer\":\"To assess intra- and inter-operator variability in manual planning for cardiovascular MR and to evaluate its influence on left ventricular functional parameters.\"},{\"question\":\"How was the imaging planning performed and who analyzed the data?\",\"answer\":\"Short-axis cine acquisitions were manually planned twice by one operator and once by a second operator. Left ventricular volume, mass, and function were manually evaluated twice by one experienced observer.\"},{\"question\":\"What did the results show about reproducibility?\",\"answer\":\"Variability differed by parameter, with small absolute differences and no significant statistical differences between intra- and inter-operator reproducibility. Bland-Altman analysis indicated no systematic bias in measurement differences.\"}]","Operator induced variability in cardiovascular MR - left ventricular measurements and their reproducibility | PDF",1792668607,28]