[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-442753-105":59,"doc-detail-442753-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","ocular-cicatricial-pemphigoid-in-a-healthy-elderly-male-filipino-patient","Ocular Cicatricial Pemphigoid in a Healthy Elderly Male Filipino Patient","","Ocular cicatricial pemphigoid is a chronic, bilateral, cicatrizing conjunctivitis with relapsing and remitting episodes that can permanently damage vision. The case involves an elderly Filipino man with bilateral ocular findings and eye involvement that improved diagnostic clarity through direct immunofluorescence assay, including asymmetry between eyes. Management included topical steroids and antibiotics, with systemic dapsone initiated by dermatology and rheumatology.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/ocular-cicatricial-pemphigoid-in-a-healthy-elderly-male-filipino-patient/442753/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/ocular-cicatricial-pemphigoid-in-a-healthy-elderly-male-filipino-patient/442753.png","ImageObject",300,407,{"name":92,"@type":93},"jayni","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is ocular cicatricial pemphigoid (OCP) in the report?","Question",{"text":112,"@type":113},"OCP is described as a chronic bilateral, non-infectious, cicatrizing conjunctivitis with relapsing and remitting periods that can lead to blindness due to fibrosis and blister formation.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What diagnostic method confirmed OCP in this patient?",{"text":117,"@type":113},"Direct immunofluorescence (DIF) assay on conjunctival biopsy supported the diagnosis, described as the gold-standard for diagnosis in the report.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the patient treated, and by whom was systemic therapy started?",{"text":121,"@type":113},"The patient received topical steroids and antibiotics for both eyes. Oral dapsone was started by dermatology and rheumatology services.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},442753,1790763051,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":34,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},3985747859343,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","CASE REPORT  \nOcular Cicatricial Pemphigoid in a Healthy Elderly Male Filipino Patient  \nJose Christopher C. Tesorero III, MD,1 George Michael N. Sosuan, MD1 and Ruben Lim Bon Siong, MD1,2  \n1Department of Ophthalmology and Visual Sciences, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines  \n2Eye Institute, St. Luke’s Medical Center, Quezon City, Philippines  \nABSTRACT  \nOcular cicatricial pemphigoid (OCP) is a chronic bilateral, blinding, cicatrizing form of conjunctivitis with relapsing andremitting periods. It has strong evidence for an immune type II hypersensitivity that leads to subconjunctival fibrosis and extensive systemic bullae formation. To the best knowledge of the authors, this is the first reported case of direct immunofluorescence (DIF) assay-proven OCP in an elderly Filipino man.  \nA 68-year-old male presented with bilateral corneal conjunctivalization, symblepharon, ectropion, conjunctival hyperemia testing positive with conjunctival biopsy for basement membrane antibodies with DIF for the left eye, while turning out negative for the right eye. He was managed as a case of OCP, both eyes, and was given topical steroids and antibiotics. Oral Dapsone was started by Dermatology and Rheumatology Services.  \nOCP is a rare autoimmune and blinding disease. Early diagnosis and prompt treatment are vital as ocular complications permanently affect the quality of life of patients as seen in our patient. DIF assay remains the gold-standard for diagnosis. Systemic immunosuppression is the mainstay of treatment. Adjunctive supportive topical medication may be given to alleviate ocular discomfort. A multidisciplinary approach is essential to provide holistic care to each patient.  \nKeywords: ocular cicatricial pemphigoid, Filipino, direct immunofluorescence assay  \neISSN 2094-9278 (Online) Published: November 28, 2025  \n[https://doi.org/10.47895/amp.vi0.12049](https://doi.org/10.47895/amp.vi0.12049)  \n[Copyright: The Author](Copyright: The Author)([s](s)) 2025  \nCorresponding author: George Michael N. Sosuan, MD Department of Ophthalmology and Visual Sciences Sentro Oftalmologico Jose Rizal  \nPhilippine General Hospital  \nUniversity of the Philippines Manila Taft Avenue, Ermita, Manila 1000, Philippines [Email: gmsosuan@yahoo.com](Email: gmsosuan@yahoo.com)  \nORCiD: [https://orcid.org/0000-0002-1306-3727](https://orcid.org/0000-0002-1306-3727)  \nINTRODUCTION  \nOcular cicatricial pemphigoid (OCP) is characterized by a chronic bilateral non-infectious, cicatrizing form of conjunctivitis with relapsing and remitting periods.1 Strong evidences exist for an autoimmune type II hypersensitivity involving autoantibodies against the integrin and laminin contents located in the hemidesmosome-epithelial membrane complex of the conjunctival squamous epithelium eventually leading to separation of the epithelium from the basement membrane with subsequent bullae formation. The migration of inflammatory cells into the substantia propria typically presents as subconjunctival fibrosis with or without inflammation. In early and acute phases, eosinophils and neutrophils mediate the inflammation; however, lymphocytes have been largely observed in chronic cases.2  \nOCP is a rare form of potentially blinding cicatrizing conjunctivitis among Filipinos and should not be missed among patients presenting with chronic bilateral conjunctivitis. Written informed consent to publication of information was obtained from the patient. To the best knowledge of the authors, this is the first reported case of ocular cicatricialpemphigoid in a healthy elderly Filipino man confirmed by direct immunofluorescence (DIF) assay. The authors aimed to report this potentially blinding disease and review  \nOCP in a Filipino Man  \nits management in the hope of better understanding of the disease process.  \nCASE PRESENTATION  \nA non-hypertensive, non-diabetic male patient in his late 60s consulted for progressive blurring of vision on the","cbCaihhsmMwcdPDe","https://ap.wps.com/l/cbCaihhsmMwcdPDe","pdf",3107634,"English","# Introduction\n# Case Presentation\n# Discussion","[{\"question\":\"What is ocular cicatricial pemphigoid (OCP) in the report?\",\"answer\":\"OCP is described as a chronic bilateral, non-infectious, cicatrizing conjunctivitis with relapsing and remitting periods that can lead to blindness due to fibrosis and blister formation.\"},{\"question\":\"What diagnostic method confirmed OCP in this patient?\",\"answer\":\"Direct immunofluorescence (DIF) assay on conjunctival biopsy supported the diagnosis, described as the gold-standard for diagnosis in the report.\"},{\"question\":\"How was the patient treated, and by whom was systemic therapy started?\",\"answer\":\"The patient received topical steroids and antibiotics for both eyes. Oral dapsone was started by dermatology and rheumatology services.\"}]","Ocular Cicatricial Pemphigoid in a Healthy Elderly Male Filipino Patient | PDF",1790701520,18]